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11 results for “Indene”
UBL000038770 - Tweeden placaet-bovck: inhovdende diversche ordonnancien, edicten, ende placaetē vande Coninclicke Ma.ten ende ... grauen van Vlaendren, metsgaders ... Prouincialen Raede aldaer, ghepubliceert inden voorghenoemden lande van Vlaendren t'zedert den iaere vyfthien-hondert t'zestich, tot ende metten iaere zesthien-hondert neghenen-twintich
<p>Titel: <em> </em><em>Tweeden placaet-bovck: </em><em>inhovdende diversche ordonnancien, edicten, ende placaetē vande Coninclicke Ma.ten ende ... grauen van Vlaendren, metsgaders ... Prouincialen Raede aldaer, ghepubliceert inden voorghenoemden lande van Vlaendren t'zedert den iaere vyfthien-hondert t'zestich, tot ende metten iaere zesthien-hondert neghenen-twintich</em></p> <p>Publisher: Anna vanden Steene, F.a Ians</p> <p>Place: Gent</p> <p>Year: 1629</p> <p>Used version: The copy we used for the transcriptions is held at Leiden University Library and digitised by the KB National Library of the Netherlands.</p> <p>Link digitised version of the book: https://books.google.nl/books?id=ptMn82qzfyQC</p> <p>(Main) Language: Dutch.</p> <p>Province: Vlaanderen</p> <p>Font: Romein.</p> <p>Model used: Dutch_Romantype_Print.</p> <p>Version of Transkribus used: v.1.9.1.</p> <p>Other info: Abbyy FineReader v.11 has been used.</p> <p>Link model: For more information on the HTR-model used, please visit: <a href="https://lab.kb.nl/dataset/entangled-histories-ordinances-low-countries">https://lab.kb.nl/dataset/entangled-histories-ordinances-low-countries</a>.</p> <p>Transcription conventions:</p> <ul> <li> <p>The abbreviations have been written out into full words.</p> </li> <li> <p>The hyphens at the end of a line have been kept (when there).</p> </li> </ul> <p>If you are in need of the original scans of the documents, please contact <a href="mailto:xxxxxx@kb.nl">dataservices@kb.nl</a>.</p> <p>This transcription is part of the dataset created with the ‘Entangled Histories’-project.</p> <p>PI: dr. C.A. Romein;<br> Scientific Programmer: S.F. Veldhoen, MSc;<br> Project Manager: drs. M. de Gruijter.</p> <p> </p>
Rh-Catalyzed [3+2] Annulation of Cyclic Ketimines and Alkynylchloride: A Novel Strategy to Access Unsymmetrically Substituted and Highly Functionalizable Indenes
<p>This zipped file is a set of original NMR data pre-uploaded to zenodo and will be linked with a scientific publication which is under peering review.</p>
Supplementary material 1 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Design, synthesis and biological evaluation of novel 2-hydroxy-1H-indene-1,3(2H)-dione derivatives as FGFR1 inhibitors
UBL000003700 - Generale ende particuliere ordonnantien, op den opheve van den generale ende gemeene middelen, inden lande ende steden der provintie van Over-Yssel: met byvoeginge van placcaten
<p>Titel: <em> </em><em>Generale ende particuliere ordonnantien, op den opheve van den generale ende gemeene middelen, inden lande ende steden der provintie van Over-Yssel</em><em>: met byvoeginge van placcaten</em></p> <p>Publisher: Gerrit Tydeman</p> <p>Place: Zwolle</p> <p>Year: 1661</p> <p>Used version: The copy we used for the transcriptions is held at Leiden University Library and digitised by the KB National Library of the Netherlands.</p> <p>Link digitised version of the book: https://books.google.nl/books?id=4dv77lsZcaIC</p> <p>(Main) Language: Dutch.</p> <p>Province: Overijssel</p> <p>Font: Gothic.</p> <p>Model used: Dutch_Gothic_Print.</p> <p>Version of Transkribus used: v.1.9.1.</p> <p>Other info: Abbyy FineReader v.11 has been used.</p> <p>Link model: For more information on the HTR-model used, please visit: <a href="https://lab.kb.nl/dataset/entangled-histories-ordinances-low-countries">https://lab.kb.nl/dataset/entangled-histories-ordinances-low-countries</a>.</p> <p>Transcription conventions:</p> <ul> <li> <p>The abbreviations have been written out into full words.</p> </li> <li> <p>The hyphens at the end of a line have been kept (when there).</p> </li> </ul> <p>If you are in need of the original scans of the documents, please contact <a href="mailto:xxxxxx@kb.nl">dataservices@kb.nl</a>.</p> <p>This transcription is part of the dataset created with the ‘Entangled Histories’-project.</p> <p>PI: dr. C.A. Romein;<br> Scientific Programmer: S.F. Veldhoen, MSc;<br> Project Manager: drs. M. de Gruijter.</p> <p> </p>
Figure 3 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Figure 3 Stick representation of a. Erdafitinib; b. 7b; c. 9a; d. 9b; e. 9c in grey colour, docked within FGFR1 (PDB ID: 5EW8) binding site (green). Generated by Biovia Discovery Studio visualizer®.
Figure 2 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Figure 2 Solid ribbon representation of FGFR1 (PDB ID: 5EW8) with co-crystal (grey) and re-docked (orange) erdafitinib. Generated by Biovia Discovery Studio visualizer®.
Figure 4 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Figure 4 Dose-response curves of compounds 7b, 9a, 9b and 9c FGFR1 inhibitor. A. Dose-response curve of 7b with IC50 = 3.1 μM; B. Dose-response curve of 9a with IC50 = 5.7 μM; C. Dose-response curve of 9b with IC50 = 3.3 μM; D. Dose-response curve of 9c with IC50 = 4.1 μM.
Scheme 1 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Scheme 1 Synthesis of 2-hydroxy-2-(imidazo[1,5-a]pyridinyl)indene-1,3(2H)-diones.
Figure 1 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Figure 1 ORTEP view of the molecular structure and atom numbering scheme of 9b.
Scheme 2 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Scheme 2 Synthesis of compounds 7–9.
Scheme 3 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Scheme 3 Synthesis of compounds 4–6.
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