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15 results for “Insect repellent”
GC-MS data set for Generation of a chromosome-scale genome assembly of the insect-repellant terpenoid-producing Lamiaceae species, Callicarpa americana
<p>RAW GC/MS data set for characterization of class II terpene synthases from <em>Callicarpa americana </em></p>
Machine Learning Models and New Computational Tool for the Discovery of Insect Repellents that Interfere with Olfaction
<ul> <li><strong>SI1_Supporting Information</strong> file (docx) brings together detailed information on the outstanding models obtained for each dataset analyzed in this study such as statistical and training parameters and outliers. There can be found the responses in spikes/s of the mosquito <em>Culex quinquefasciatus </em>to the 50 IRs. Besides, there is presented a full table of the up-to-date studies related to QSAR and insect repellency.</li> <li><strong>SI2_EXP1_50IRs from Liu et al (2013)</strong> SDF file presents the structures of each of the 50 IRs analyzed.</li> <li><strong>SI3_EXP2_Datasets</strong> gathers the four datasets as SDF files from Oliferenko <em>et al.</em> (2013), Gaudin<em> et al. </em>(2008), Omolo <em>et al.</em> (2004), and Paluch <em>et al.</em> (2009) used for the repellency modeling in <strong>EXP2</strong>.</li> <li><strong>SI4_EXP3_Prospective analysis </strong>provides Malaria Box Library (400 compounds) as an SDF file, which were analyzed in our virtual screening to prospect potential virtual hits.</li> <li><strong>SI5_QuBiLS-MIDAS MDs lists</strong> contain three TXT lists of 3D molecular descriptors used in QuBiLS-MIDAS to describe the molecules used in the present study.</li> <li><strong>SI6_EXP1_Sensillar Modeling</strong> comprises two subfolders: Classification and Regression models for each of the six sensilla. Models built to predict the physiological interaction experimentally obtained from Liu <em>et al.</em> (2013). All of the models are implemented in the software SiLiS-PAPACS. Every single folder compiles a DOCX file with the detailed description of the model, an XLSX file with the output obtained from the training in Weka 3.9.4, an ARFF, and CSV files with the MDs for each molecule, and the SDF of the study dataset.</li> <li><strong>SI7_EXP2_Repellency Modeling </strong>encompasses the four datasets in the study: Oliferenko <em>et al.</em> (2013), Gaudin<em> et al. </em>(2008), Omolo <em>et al.</em> (2004), and Paluch <em>et al.</em> (2009). Inside the subfolders, there are three models per type of MDs (duplex, triple, generic, and mix) selected that best predict each dataset. As well as the SI6 folder, each model includes six files: DOCX, XLSX, ARFF, CSV, and an SDF.</li> <li><strong>SI8_Virtual Hits </strong>includes the cluster analysis results and physico-chemical properties of new IR virtual leads.</li> </ul>
Generation of a chromosome-scale genome assembly of the insect-repellant terpenoid-producing Lamiaceae species, Callicarpa americana
<p>Background: Plants exhibit wide chemical diversity due to production of specialized metabolites which function as pollinator attractants, defensive compounds, and signaling molecules. Lamiaceae (mints) are known for their chemodiversity and have been cultivated for use as culinary herbs and as sources of insect repellents, health-promoting compounds, and fragrance. Findings: We report the chromosome-scale genome assembly of <em>Callicarpa americana</em> L. (American beautyberry), a species within the early diverging Callicarpoideae clade of the Lamiaceae, known for its metallic purple fruits and use as an insect repellent due to its production of terpenoids. Using long reads and Hi-C scaffolding, we generated a 506.1 Mb assembly spanning 17 pseudomolecules with an N50 contig and N50 scaffold size of 7.5 Mb and 29.0 Mb, respectively. A total of 32,164 genes was annotated including 53 candidate terpene synthases and 47 putative clusters of specialized metabolite biosynthetic pathways. Whole genome duplication analyses revealed three putative events, which together with local tandem duplication events, contributed to gene family expa, American beautyberransion of terpene synthases. Kolavenyl diphosphate is a gateway to many of <em>C. americana</em>'s bioactive terpenoids; experimental validation confirmed that CamTPS2 encodes kolavenyl diphosphate synthase. Syntenic analyses with <em>Tectona grandis</em> L. f. (teak), a member of the Tectonoideae clade of Lamiaceae known for exceptionally strong wood resistant to insects, revealed 963 collinear blocks and 21,297 <em>C. americana</em> syntelogs. Conclusions: Access to the <em>C. americana</em> genome provides a roadmap for rapid discovery of genes encoding plant-derived agrichemicals and a key resource to understand the evolution of chemical diversity in Lamiaceae. </p> <p> </p>
Safety of a topical insect repellent (picaridin) during community mass use for malaria control in rural Cambodia
<p>Raw data table (sheet 2) and description of variable names (sheet 1) of the perceived side effects data from the mass use of picaridin in rural Cambodia, associated with table 5 and figure 4 in the manuscript.</p>
Data from: A phantom ultrasonic insect chorus repels low-flying bats, but most are undeterred
<p><b>Abstract</b></p> <p>1. The acoustic environment can serve as a niche axis, structuring animal behaviour by providing or obscuring salient information. Meadow katydid choruses occupy the ultrasonic, less studied, realm of this acoustic milieu, form dense populations in some habitats, and present a potential sensory challenge to co-occurring ultrasonic-hearing animals. Aerial-hawking insectivorous bats foraging immediately over vegetation must listen for echoes of their prey and other cues amidst the chorus din.</p> <p>2. We experimentally created the cacophony of a katydid chorus in a katydid-free rice paddy using an aggregation of 100 ultrasonic speakers in a 25 x 25 m grid to test the hypothesis that aerially hawking bats are averse to this noise source. We alternated between chorus-on and chorus-off hourly, and acoustically monitored bat activity and arthropod prey abundance.</p> <p>3. We found that our phantom katydid chorus reduced bat activity nearest the sound source by 39.3% (95% CI: 7.8 - 60.0%) for species whose call spectrum fully overlapped with the chorus, and elicited marginal reductions in activity in species with only partial spectral overlap.</p> <p>4. Our study suggests that ultrasonic insect choruses degrade foraging habitat, potentially suppressing bats' ecosystem services as consumers of pests; and, given the global distribution of meadow katydids, may provide an underappreciated force modifying animal behaviour in other grassland habitats.</p>
Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR
ClinicalTrials.gov study NCT00938379. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Testing Insect Repellents Against Musca Sorbens, the Vector of Trachoma
ClinicalTrials.gov study NCT03813069. IPD Sharing: YES. Countries: 2. Publications: 25.
Generation of a chromosome-scale genome assembly of the insect-repellant terpenoid-producing Lamiaceae species, Callicarpa americana
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Data from: A phantom ultrasonic insect chorus repels low-flying bats, but most are undeterred
Open the record for dataset details and reuse information.
Data from: Water-repellent plant surface structure induced by gall-forming insects for waste management
Many animals and plants have evolved elaborate water-repellent microstructures on their surface, which often play important roles in their ecological adaptation. Here we report a unique type of water-repellent structure on plant surface, which develops as an insect-induced plant morphology in a social context. Some social aphids form galls on their host plant, in which they produce large amount of hydrophobic wax. Excreted honeydew is coated by the powdery wax to form "honeydew balls", which are actively disposed by soldier nymphs through an opening on their gall. These activities are enabled by a highly water-repellent inner gall surface, and we discovered that this surface is covered with dense trichomes that are not found on normal plant surface. The trichomes are coated by fine particles of the insect-produced wax, thereby realizing a high water repellency with a cooperative interaction between aphids and plants. The plant leaves on which the gall is formed often exhibit patchy areas with dense trichomes, representing an ectopic expression of the insect-induced plant morphology. In the pouch-shaped closed galls of a related social aphid species, by contrast, the inner surface was not covered with trichomes. Our findings provide a convincing example of how the extended phenotype of an animal, expressed in a plant, plays a pivotal role in maintaining sociality.
Evaluation of Combined Use of ITN's and Insect Repellents Against Malaria
ClinicalTrials.gov study NCT00144716. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Data from: Water-repellent plant surface structure induced by gall-forming insects for waste management
Open the record for dataset details and reuse information.
Pesticide and Insect Repellent Mixture (Permethrin and DEET) Induces Epigenetic Transgenerational Inheritance of Disease and Sperm Epimutations
GEO Series GSE59554. Rattus norvegicus. 3 samples. Type: Methylation profiling by genome tiling array.
Field Evaluation of Two Topically Applied Insect Repellent Products Containing IR3535 Against Mosquitos in Louisiana
ClinicalTrials.gov study NCT05394597. IPD Sharing: NO. Countries: 1. Publications: 0.
Determining the Complete Protection Time of an Insect Repellent With 30% Citriodiol® Against Three Species of Ticks.
ClinicalTrials.gov study NCT03708120. IPD Sharing: NO. Countries: 1. Publications: 0.
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OpenNeuro
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