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266 results for “Ketogenic Diet”
Feasibility and metabolic outcomes of a well-formulated ketogenic diet as an adjuvant therapeutic intervention for women with stage IV metastatic breast cancer: The Keto-CARE trial
<p><em>Purpose:</em></p> <p>Ketogenic diets may positively influence cancer through pleiotropic mechanisms, but only a few small and short-term studies have addressed feasibility and efficacy in cancer patients. The primary goals of this study were to evaluate the feasibility and the sustained metabolic effects of a personalized well-formulated ketogenic diet (WFKD) designed to achieve consistent blood beta-hydroxybutyrate (<span>β</span>HB) >0.5 mM in women diagnosed with stage IV metastatic breast cancer (MBC) undergoing chemotherapy.</p> <p><em>Methods: </em></p> <p>Women (n = 20) were enrolled in a six-month two-phase, single-arm WFKD intervention (NCT03535701). Phase I was a highly-supervised, ad libitum, personalized WFKD, where women were provided with ketogenic-appropriate food daily for three-months. Phase II transitioned women to a self-administered WFKD with ongoing coaching for an additional three-months. Fasting capillary <span>β</span>HB and glucose were collected daily; weight, body composition, plasma insulin, and insulin resistance were collected at baseline, three- and six-months. </p> <p><em>Results:</em></p> <p>Capillary <span>β</span>HB indicated women achieved nutritional ketosis (Phase I mean: 0.8 mM (n = 15); Phase II mean: 0.7 mM (n = 9)). Body weight decreased 10% after three-months, primarily from body fat. Fasting plasma glucose, plasma insulin, and insulin resistance also decreased significantly after three-months (p < 0.01), an effect that persisted at six-months.</p> <p><em>Conclusions</em>:</p> <p>Women diagnosed with MBC undergoing chemotherapy can safely achieve and maintain nutritional ketosis, while improving body composition and insulin resistance, out to six-months.</p>
Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents
ClinicalTrials.gov study NCT06920940. IPD Sharing: YES. Countries: 1. Publications: 13.
The Effect of Ketogenic-caloric Restricted Diet on Metabolic Endotoxemia in Prediabetic Obese Adults
ClinicalTrials.gov study NCT06911879. IPD Sharing: NO. Countries: 1. Publications: 0.
Compatibility of C7 With Ketogenic Diet in Patients Diagnosed With G1D
ClinicalTrials.gov study NCT03301532. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Calorie-restricted, Ketogenic Diet and Transient Fasting During Reirradiation for Patients With Recurrent Glioblastoma
ClinicalTrials.gov study NCT01754350. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Ketogenic Diet in Advanced Cancer
ClinicalTrials.gov study NCT01716468. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss
ClinicalTrials.gov study NCT00108524. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Ketogenic Diet for Recurrent Glioblastoma
ClinicalTrials.gov study NCT00575146. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Ketogenic Diet Therapy Major Depressive Disorder
ClinicalTrials.gov study NCT05558995. IPD Sharing: NO. Countries: 1. Publications: 7.
Ketogenic Diet (KD) in Alcoholism
ClinicalTrials.gov study NCT03255031. IPD Sharing: NO. Countries: 1. Publications: 5.
Feasibility and metabolic outcomes of a well-formulated ketogenic diet as an adjuvant therapeutic intervention for women with stage IV metastatic breast cancer: The Keto-CARE trial
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Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools
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Effects of a Ketogenic Diet on PCOS Outcomes
ClinicalTrials.gov study NCT04163120. IPD Sharing: NO. Countries: 1. Publications: 7.
Very Low Calorie Ketogenic Low-fat Diet (VLCKLFD)
ClinicalTrials.gov study NCT06275347. IPD Sharing: NO. Countries: 1. Publications: 19.
Multiple Sclerosis and the Effects of Ketogenic Diet Therapy
ClinicalTrials.gov study NCT06715436. IPD Sharing: NO. Countries: 1. Publications: 23.
The Effects of Ketogenic Diet on the Heart and Brain
ClinicalTrials.gov study NCT05012748. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma
ClinicalTrials.gov study NCT05119010. IPD Sharing: UNDECIDED. Countries: 1. Publications: 63.
Therapeutic Ketogenic Diet in Partial Hospital Program (PHP) Anorexia Nervosa
ClinicalTrials.gov study NCT06605027. IPD Sharing: NO. Countries: 1. Publications: 4.
Ketogenic Diet to Improve Neuro-recovery
ClinicalTrials.gov study NCT03509571. IPD Sharing: NO. Countries: 1. Publications: 1.
Impact of Ketogenic Diet on Lipoproteins in Refractory Epilepsy
ClinicalTrials.gov study NCT02644239. IPD Sharing: Not stated. Countries: 1. Publications: 13.
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