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853 results for “Knockout mice”
Data set of pup retrieval test in control and V1b vasopressin receptor knockout mice
<div> <div> <div> <p>This repository contains the images and code used in the paper "Computer vision analysis of mother-infant interaction identified efficient pup retrieval in V1b receptor knockout mice".</p> <p>For effective nursing, close contact between lactating mothers and their infants is necessary. However, evaluation of maternal motivation to retrieve pups is challenging, because multiple infants were randomly accessed multiple times in changing background. We applied computer vision and deep learning analysis in this process to precisely calculate maternal behavior. Object detection in an open filed test identified less entry into the center area and less moving distance in virgin female mice lacking V1b vasopressin receptor (V1bKO) than wild-type (WT) mice. Although this character was replicated in a V1bKO mother, a pup retrieval test showed that total distances among a V1bKO mother and infants come closer in a shorter time than with a WT mother. In the medial preoptic area, V1b receptor message was partly detected in galanin- and c-fos-positive neurons after the mother was stimulated by infants. Our deep learning analysis effectively evaluated mother-infant relationship in V1bKO mice.</p> </div> </div> </div>
Data_Figure1(A-D)_AKR1D1 knockout mice develop a sex dependent metabolic phenotype
<p>Data of Fig1 Pannel A-D, “AKR1D1 knockout mice develop a sex dependent metabolic phenotype”</p> <p>The Dataset contains the original figure 1 (Pannel A-D) as PNG-format (10.1530JOE-21-0280_Fig1A-D.PNG). Corresponding raw from LC-MS/MS measurements are provided as one file in CSV format (31003A-179400_10.1530_JOE-21-0280_AKR1D1_SS_DVK_4_Fig1.csv), all further experiment related information (meta-data) as one file in TXT format (31003A-179400_10.1530_JOE-21-0280_AKR1D1_SS_DVK_4_Fig1_M1.txt), one file in PDF format (31003A-179400_10.1530_JOE-21-0280_AKR1D1_SS_DVK_4_Fig1_M2.pdf) and one file as CSV format (31003A-179400_10.1530_JOE-21-0280_AKR1D1_SS_DVK_4_Fig1_M3.csv).</p>
Data From: Global huntingtin knockout in adult mice leads to fatal neurodegeneration that spares the pancreas
Open the record for dataset details and reuse information.
OGD triggered Zn2+ rises and Ca2+ deregulation events in CA1 and CA3 hippocampal pyramidal neurons of MT-III and ZnT3 knockout mice.
<p>The posted data provide the control characterization of the oxygen glucose deprivation (OGD) triggered occurrences of cytosolic Zn<sup>2+</sup> rises and terminal Ca<sup>2+</sup> deregulation events in individual CA1 and CA3 pyramidal neurons in acute hippocampal slices of the MT-III knockout mice ( <strong>004649 - 129S7-Mt3<sup>tm1Rpa</sup>/J</strong>, Jackson Laboratory) and ZnT3 knockout mice ( <strong>005064 -</strong> <strong>B6;129-Slc30a3<sup>tm1Rpa</sup>/J</strong>, Jackson Laboratory).</p>
Ndufs4 knockout mice with isolated complex I deficiency engage a futile adaptive brain response - supplementary data
<p>This study aims to provide insight into the Leigh Syndrome pathomechanism at the sub-brain level. To this end, a comparative proteome analysis was performed on various brain regions of 6 wildtype (WT) and 6 whole body (WB) Ndufs4-/- (WB-KO) mice over two experiments. Samples were collected at six weeks after birth (i.e. ~ one week prior to WB-KO death). For the first experiment samples were collected from a brain slice (BrSl), which contained (parts of) the CC, HC, hypothalamus, thalamus, caudate putamen, and olfactory areas. For the second experiment the analysed brain regions consisted of cerebellum (CB), cerebral cortex (CC), hippocampus (HC), inferior colliculust (IC), and superior colliculus (SC).</p>
Knockout mice represent an important tool for the multisystemic study of human monogenic heart disease
<p>Supplementary data to support a manuscript entitled "Knockout mice represent an important tool for the multisystemic study of human monogenic heart disease"</p>
Effects of Myostatin gene knockout on white fat browning and related gene expression in type 2 diabetic mice
<p><strong>Supplementary material</strong></p>
Gene expression data from acetaminophen-induced toxicity in wild-type and Gα12 knockout mice
GEO Series GSE173595. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profilling of liver from C57BL/6 wildtype and PPARα-knockout mice treated with PFOA and GenX after 20 weeks of high-fat diet
GEO Series GSE212294. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
Cellular origin, tumour progression and pathogenic mechanisms of cutaneous neurofibromas revealed by mice with Nf1 knockout in boundary cap cells
GEO Series GSE117781. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Knockout mice reveal an essential role for Epithelial splicing regulatory proteins (Esrps) in mammalian development and epithelial splicing in vivo
GEO Series GSE64357. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
The effect of active YAP in neonatal heart of Xinβ knockout mice
GEO Series GSE149647. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Nutritional effects by beta-carotene in liver in males and females of control wildtype mice versus BCMO knockout mice
GEO Series GSE98846. Mus musculus. 48 samples. Type: Expression profiling by array.
Quantitative Transcriptome Analysis of the Stomach Neck Mucosa from Control vs Claudin (CLDN)-18 knockout mice.
GEO Series GSE93774. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
H3K27me3 Cut&Tag profiling of bone marrow-derived alveolar macrophages from wildtype and Suz12 knockout mice
GEO Series GSE176148. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Next generation sequencing of CD11b+ cells from female and male Wildtype and Cystatin C knockout mice with experimental allergic encephalomyelitis (EAE)
GEO Series GSE157624. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
Gene expression data of islets from Zzef1 global knockout (Zzef1_KO) mice and littermate controls (WT) mice fed with normal-chow diet (NCD) [bulk RNA-seq]
GEO Series GSE223143. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analyses of skeletal muscle in αB-crystallin/HspB2 knockout and wild-type mice on a normal or high fat diet
GEO Series GSE66557. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Comparative gene expression profiling of RNA-seq data from islets of β-cell-specific ZZEF1 knockout mice (βZKO-Mip) and their littermate controls, treated with either azoramide or DMSO.
GEO Series GSE288210. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
RNA Seq of Subcutaneous adipose tissue from endothelial-AGO1-knockout (EC-AGO1-KO) mice and wild-type (WT) littermates
GEO Series GSE136910. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.