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Dataset results
29 results for “Leber hereditary optic neuropathy”
Genetic variants affecting NQO1 protein levels impact on efficacy of idebenone treatment in Leber hereditary optic neuropathy
<p>Fastq files with complete sequencing of NQO1 gene after PCR amplification for cell lines harboring m.11778G>A/MT-ND4 or m.3460A>G/MT-ND1 and controls.</p>
Multishell Diffusion MR Tractography Yields Morphological and Microstructural Information of the Anterior Optic Pathway: A Proof-of-Concept Study in Patients with Leber's Hereditary Optic Neuropathy. RAW DATA
<p>Raw data used to prepare Figures and Tables in article "Multishell Diffusion MR Tractography Yields Morphological and Microstructural Information of the Anterior Optic Pathway: A Proof-of-Concept Study in Patients with Leber’s Hereditary Optic Neuropathy", accepted for publication at International Journal of Environmental Research and Public Health, 27 May 2022.</p>
Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy
ClinicalTrials.gov study NCT02161380. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON)
ClinicalTrials.gov study NCT01267422. IPD Sharing: NO. Countries: 1. Publications: 32.
Study to Assess Efficacy,Safety and Tolerability of Idebenone in the Treatment of Leber's Hereditary Optic Neuropathy
ClinicalTrials.gov study NCT00747487. IPD Sharing: Not stated. Countries: 3. Publications: 2.
A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy
ClinicalTrials.gov study NCT03153293. IPD Sharing: NO. Countries: 1. Publications: 19.
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Q
ClinicalTrials.gov study NCT05555784. IPD Sharing: NO. Countries: 1. Publications: 5.
Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy
ClinicalTrials.gov study NCT02176733. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)
ClinicalTrials.gov study NCT01389817. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy
ClinicalTrials.gov study NCT02693119. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy
ClinicalTrials.gov study NCT07258667. IPD Sharing: YES. Countries: 1. Publications: 0.
Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)
ClinicalTrials.gov study NCT02796274. IPD Sharing: Not stated. Countries: 7. Publications: 0.
Data from: Measurement of systemic mitochondrial function in advanced primary open-angle glaucoma and Leber hereditary optic neuropathy
Open the record for dataset details and reuse information.
OXPHOS bioenergetic compensation does not explain disease penetrance in Leber hereditary optic neuropathy
GEO Series GSE144914. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Establishment of human Leber’s hereditary optic neuropathy model using iPSC-derived retinal organoids
GEO Series GSE305550. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
dateset relate to article (submitted) Evaluation of mitochondrial dysfunction and idebenone responsiveness in fibroblasts from Leber's Hereditary Optic Neuropathy (LHON) subjects.
<p>raw data related to the article at title</p>
A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)
ClinicalTrials.gov study NCT00528151. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients
ClinicalTrials.gov study NCT02064569. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy
ClinicalTrials.gov study NCT04912843. IPD Sharing: NO. Countries: 1. Publications: 0.
Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey
ClinicalTrials.gov study NCT01892943. IPD Sharing: Not stated. Countries: 5. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.