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Dataset results
40 results for “Leukodystrophies”
PDB File and MD Simulation results for "The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy"
<p>Supplementary structural file for article: "The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy":</p> <p>-Predicted Structure of DEGS1 docked to C16 Ceramide in PDB format</p> <p>- 2.5 µsec Molecular Dynamics Simulation of this DEGS1-Ceramide complex embedded in a DPPC membrane and surrounded by TIP3 water and 150 mM NaCl as mp4 (movies) or as original trajectory. In the version with the smaller file size solvent molecules and the membrane are invisible for clarity. </p> <p>Software/Webservices used for generation: AlphaFold, PPM3 web server, CHARM-GUI PDB Manipulator, Maestro/Glide/Ligprep/Desmond (Schrödinger Inc.).</p> <p>Version 1 contained videos in mpeg format that caused error with some players. In Version 2 videos are converted to mp4. </p>
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
ClinicalTrials.gov study NCT02699190. IPD Sharing: NO. Countries: 1. Publications: 10.
Metazym for the Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)
ClinicalTrials.gov study NCT00418561. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD)
ClinicalTrials.gov study NCT01510028. IPD Sharing: NO. Countries: 5. Publications: 1.
Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)
ClinicalTrials.gov study NCT00633139. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Safety and Efficacy Study of Cryopreserved OTL-200 for Treatment of Metachromatic Leukodystrophy (MLD)
ClinicalTrials.gov study NCT03392987. IPD Sharing: NO. Countries: 1. Publications: 1.
Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy
ClinicalTrials.gov study NCT02559830. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Intracerebral Gene Therapy for Children With Early Onset Forms of Metachromatic Leukodystrophy
ClinicalTrials.gov study NCT01801709. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Aclarubicin for the Treatment of Retinal Vasculopathy With Cerebral Leukodystrophy
ClinicalTrials.gov study NCT02723448. IPD Sharing: YES. Countries: 1. Publications: 6.
The Nosology and Etiology of Leukodystrophies of Unknown Causes
ClinicalTrials.gov study NCT00889174. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Study of Intrathecal SHP611 in Children With Metachromatic Leukodystrophy
ClinicalTrials.gov study NCT03771898. IPD Sharing: YES. Countries: 14. Publications: 0.
Modeling Macrophages Activation Pattern in X-linked Adrenoleukodystrophy, Metachromatic Leukodystrophy and Adult Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia
ClinicalTrials.gov study NCT04925349. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Gene Therapy for Metachromatic Leukodystrophy (MLD)
ClinicalTrials.gov study NCT01560182. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Data from: Brain MRI features and scoring of leukodystrophy in adult-onset Krabbe disease
Open the record for dataset details and reuse information.
Dataset relate to article "Severe Epilepsy and Movement Disorder May Be Early Symptoms of TMEM106B-Related Hypomyelinating Leukodystrophy"
<p>single patient’s clinical data</p>
Characterization and Outcome of Children With Leukodystrophy: An Observational Study at Sohag University Hospital
ClinicalTrials.gov study NCT04781010. IPD Sharing: YES. Countries: 0. Publications: 2.
The Classification and Cause of Leukodystrophies of Unknown Cause
ClinicalTrials.gov study NCT00001671. IPD Sharing: Not stated. Countries: 4. Publications: 4.
A Study to Learn About Metachromatic Leukodystrophy (MLD) in Children in Spain
ClinicalTrials.gov study NCT05755568. IPD Sharing: NO. Countries: 1. Publications: 0.
Identifying Altered Developmental Pathways in Induced Pluripotent Stem Cell-Derived Neural Stem Cells From a Patients with Globoid Cell Leukodystrophy Using Transcriptome Profiling
GEO Series GSE212512. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile of patients affected by Metachromatic Leukodystrophy (MLD)
GEO Series GSE23350. Homo sapiens. 48 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.