Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
7
datasets available to search
ShareScore release 0.9.0
Dataset results
7 results for “Littorina fabalis”
An allozyme polymorphism is associated with a large chromosomal inversion in the marine snail Littorina fabalis
<p>This Zenodo archive contains the dataset analysed in the paper "An allozyme polymorphism is associated with a large chromosomal inversion in the marine snail Littorina fabalis" published in Evolutionary Application in 2022:</p> <ul> <li><a href="https://zenodo.org/api/files/cd560cff-56d4-4f72-95be-e70939f2b85f/FAB_LG3_maf1_SNP_Hexcess_depth10.vcf">FAB_LG3_maf1_SNP_Hexcess_depth10.vcf </a>: vcf for LG3 unpruned for LD containing 295 individuals genotyped at 58,246 filtered SNPs</li> <li><a href="https://zenodo.org/api/files/cd560cff-56d4-4f72-95be-e70939f2b85f/FAB_LG3_maf1_SNP_Hexcess_depth10_thin.vcf">FAB_LG3_maf1_SNP_Hexcess_depth10_thin.vcf </a>: vcf for LG3 pruned for LD containing 295 individuals genotyped at 9,905 filtered SNPs</li> <li><a href="https://zenodo.org/api/files/cd560cff-56d4-4f72-95be-e70939f2b85f/FAB_AK_maf1_SNP_Hexcess_depth10.vcf">FAB_AK_maf1_SNP_Hexcess_depth10.vcf</a> : vcf for contig265 containing the arginine kinase gene: 295 individuals genotyped at 70 filtered SNPs</li> </ul> <p>The archive also include some of the R script used to performed the analyses of the manuscrit:</p> <ul> <li> </li> <li><a href="https://zenodo.org/api/files/cd560cff-56d4-4f72-95be-e70939f2b85f/Population_genetic_Ark_analyses.R">Population_genetic_Ark_analyses.R </a>: Script to perform PCA +phenotypic cline + FST + Hobs + FIS</li> <li><a href="https://zenodo.org/api/files/cd560cff-56d4-4f72-95be-e70939f2b85f/Suspension_bridge_fit.R">Suspension_bridge_fit.R </a>: Script to perform the suspension bridge fit used to found evidence of gene flux inside the inversion.</li> <li><a href="https://zenodo.org/api/files/cd560cff-56d4-4f72-95be-e70939f2b85f/Cline_function.R">Cline_function.R </a>: function used to fit the allelic frequency variation (cline) along the transect</li> </ul> <p>The raw sequences are available in NCBI.</p> <p>Abstract of the study: Understanding the genetic targets of natural selection is one of the most challenging goalsof population genetics. Some of the earliest candidate genes were identified from associations between allozyme allele frequencies and environmental variation. One such example is the clinal polymorphism in the arginine kinase (<em>Ak</em>) gene in the marine snail <em>Littorina fabalis</em>. While other enzyme loci do not show differences in allozyme frequencies among populations, the <em>Ak</em> alleles are near differential fixation across repeated wave exposure gradients in Europe. Here, we use this case to illustrate how a new sequencing toolbox can be employed to characterize the genomic architecture associated with historical candidate genes. We found that the <em>Ak</em> alleles differ by 9 non-synonymous substitutions, which perfectly explain the different migration patterns of the allozymes during electrophoresis. Moreover, by exploring the genomic context of the <em>Ak</em> gene, we found that the three main <em>Ak</em> alleles are located on different arrangements of a putative chromosomal inversion that reaches near fixation at the opposing ends of two transects covering a wave exposure gradient. This shows <em>Ak</em> is part of a large (3/4 of the chromosome) genomic block of differentiation, in which <em>Ak</em> is unlikely to be the only target of divergent selection. Nevertheless, the non-synonymous substitutions among <em>Ak</em> alleles and the complete association of one allele with one inversion arrangement suggest that the <em>Ak</em> gene is a strong candidate to contribute to the adaptive significance of the inversion.</p> <p> </p> <p> </p>
AFLP and geometric morphometrics for Littorina fabalis
<p>Low dispersal marine intertidal species facing strong divergent selective pressures associated with steep environmental gradients have a great potential to inform us about local adaptation and reproductive isolation. Among these, gastropods of the genus Littorina offer a unique system to study parallel phenotypic divergence resulting from adaptation to different habitats related with wave exposure. In this study, we focused on two Littorina fabalis ecotypes from Northern European shores and compared the patterns of habitat-related phenotypic and genetic divergence across three different geographic levels (local, regional and global). Geometric morphometric analyses revealed that individuals from habitats moderately exposed to waves usually present a larger shell size with a wider aperture than those from sheltered habitats. The phenotypic clustering of L. fabalis by habitat across most locations (mainly in terms of shell size) support an important role of ecology in morphological divergence. A genome scan based on amplified fragment length polymorphisms (AFLPs) revealed a heterogeneous pattern of differentiation across the genome between populations from the two different habitats, suggesting ecotype divergence in the presence of gene flow. The contrasting patterns of genetic structure between nonoutlier and outlier loci, and the decreased sharing of outlier loci with geographic distance among locations are compatible with parallel evolution of phenotypic divergence, with an important contribution of gene flow and/or ancestral variation. In the future, model-based inference studies based on sequence data across the entire genome will help unravelling these evolutionary hypotheses, improving our knowledge about adaptation and its influence on diversification within the marine realm.</p>
AFLP and geometric morphometrics for Littorina fabalis
Open the record for dataset details and reuse information.
Data from: Hybridization patterns between two marine snails, Littorina fabalis and L. obtusata
<p>Characterizing the patterns of hybridization between closely related species is crucial to understand the role of gene flow in speciation. In particular, systems comprising multiple contacts between sister species offer an outstanding opportunity to investigate how reproductive isolation varies with environmental conditions, demography and geographic contexts of divergence. The flat periwinkles, <i>Littorina obtusata</i> and <i>L. fabalis</i> (Gastropoda)<u>,</u><i> </i>are two intertidal sister species with marked ecological differences compatible with late stages of speciation. Although hybridization between the two was previously suggested, its extent across the Atlantic shores of Europe remained largely unknown. Here, we combined genetic (microsatellites and mtDNA) and morphological data (shell and male genital morphology) from multiple populations of flat periwinkles in north-western Iberia to assess the extent of current and past hybridization between <i>L. obtusata</i> and <i>L. fabalis</i> under two contrasting geographic settings of divergence (sympatry and allopatry). Hybridization signatures based on both mtDNA and microsatellites were stronger in sympatric sites, although evidence for recent extensive admixture was found in a single location. Misidentification of individuals into species based on shell morphology was higher in sympatric than in allopatric sites. However, despite hybridization, species distinctiveness based on this phenotypic trait together with male genital morphology remained relatively high. The observed variation in the extent of hybridization among locations provides a rare opportunity for future studies on the consequences of different levels of gene flow for reinforcement, thus informing about the mechanisms underlying the completion of speciation.</p>
Negative frequency dependent selection maintains shell banding polymorphisms in two marine snails (Littorina fabalis and L. saxatilis)
<p>The presence of shell bands is common in gastropods. The marine snails, <i>Littorina fabalis</i> and <i>L. saxatilis</i>, are<i> </i>both polymorphic for this trait. Such polymorphism would be expected to be lost by the action of genetic drift or directional selection, but it appears to be widespread at relatively constant frequencies. This suggests it is maintained by balancing selection on the trait or on a genetically linked trait. Using long time-series of empirical data, we compared potential effects of genetic drift and negative frequency-dependent selection, in the two species. The contribution of genetic drift to changes in the frequency of bands in <i>L. fabalis</i> was estimated using the effective population size estimated from microsatellite data, while the effect of genetic drift in <i>L. saxatilis</i> were derived from previously published study. Frequency-dependent selection was assessed comparing the cross-product estimator of fitness with the frequency of the polymorphism across years using a regression analysis. Both studied species showed patterns of negative frequency-dependent selection. In addition, in <i>L. fabalis</i>, contributions from genetic drift could explain some of the changes in banding frequency. Overdominance and heterogeneous selection did not fit well to our data. The possible biological explanations resulting on the maintenance of the banding polymorphism are discussed.</p>
Negative frequency dependent selection maintains shell banding polymorphisms in two marine snails (Littorina fabalis and L. saxatilis)
Open the record for dataset details and reuse information.
Data from: Hybridization patterns between two marine snails, Littorina fabalis and L. obtusata
Open the record for dataset details and reuse information.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.