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54 results for “Living Conditions”
LivWell: a sub-national database on the Living conditions of Women and their Well-being for 52 countries
<p>LivWell is a global longitudinal database which provides a range of key indicators related to women’s socioeconomic status, health and well-being, access to basic services, and demographic outcomes. Data are available at the sub-national level for 52 countries and 447 regions. A total of 134 indicators are based on 199 Demographic and Health Surveys for the period 1990-2019, supplemented by extensive information on socioeconomic and climatic conditions in the respective regions for a total of 190 indicators. The resulting data offer various opportunities for policy-relevant research on gender inequality, inclusive development, and demographic trends at the sub-national level.</p> <p>For a full description, please refer to the article describing the database here: (link to come)</p> <p>The companion repository <em>livwelldata </em>allows to easily use the database in R. The R package can be downloaded following the instructions on the following git repository: https://gitlab.pik-potsdam.de/belmin/livwelldata. The version of the database in the package is the same as in this repository.</p>
Connected Healthcare for Individuals Living at Home With Chronic Conditions
ClinicalTrials.gov study NCT04339296. IPD Sharing: NO. Countries: 1. Publications: 2.
Free‐living and symbiotic lifestyles of a thermotolerant coral endosymbiont display profoundly distinct transcriptomes under both stable and heat stress conditions
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Data from: Parameterizing the robust design in the BUGS language: lifetime carry‐over effects of environmental conditions during growth on a long‐lived bird
1. Since the initial development of the robust design, this capture‐recapture model structure has been modified to estimate temporary emigration, and expanded to include auxiliary information such as band recovery and live resight data using maximum likelihood approaches. These developments have allowed investigators to separately assess individual and group effects on true survival, site fidelity, and temporary emigration. Additionally, recent advances in the BUGS language have allowed researchers to develop increasingly complex, user‐specified models in Bayesian frameworks. 2. The robust design has rarely been implemented in the BUGS language, and previous attempts to parameterize the robust design in BUGS exhibited strong bias in estimates of temporary emigration rates. Given the limitations of current parameterizations of the robust design in Bayesian frameworks, and our research objectives, we have developed a parameterization of the robust design in the BUGS language that produces unbiased estimates of all model parameters. 3. We use this novel model structure to examine lifetime carry‐over effects of environmental conditions during early life on annual breeding probabilities of Pacific black brent (Branta bernicla nigricans) breeding on the Yukon‐Kuskokwim River Delta in western Alaska. We found that individuals that were more structurally developed as goslings bred at increased rates as adults (β = 0.14, f = 0.94), with no effect on adult survival (β = 0.01, f = 0.62). Additionally, we provide evidence for long‐term declines in apparent survival of breeding adult females at the population level (β = ‐0.01, f = 0.90). 4. This novel model structure can be easily expanded (Gibson et al., in review), and has important implications for population modelling at broad scales, where we apply it to a declining population of Pacific black brent. Given long‐term declines in gosling growth on the Yukon‐Kuskokwim Delta, we predict future declines in population trajectories as a result of lifetime carry‐over effects of environmental conditions during growth on adult fecundity, and long‐term declines in adult survival.
LOCKED: A dataset of sociodemographic, economic, living, and health features to measure the impact of the Spanish lockdown during COVID-19 on mental health conditions
<p>A dataset aimed at enhancing the understanding of the mental health effects of the COVID-19 lockdown in Spain. This dataset serves as a valuable resource by integrating psychological assessments, such as the SA-45 pyschological test, with comprehensive socioeconomic, living, and health-related information. By combining these diverse data points, the dataset enables researchers to analyze how various invidual factors influenced nine mental health conditions during the lockdown, providing a robust foundation for further studies on this critical topic.</p>
A dataset of community perspectives on living conditions and disaster risk management in informal settlements: A case study in KwaZulu-Natal Province, South Africa
<p>This article describes a dataset of community perspectives on living conditions and disaster risk management in Khan Road, a non-serviced informal settlement, located in Pietermaritzburg, the capital of KwaZulu-Natal province in South Africa. The data were collected by local community researchers via a structured questionnaire of 159 participants conducted between August and September 2022, using mobile phones via KoboToolbox. The dataset was analysed using exploratory data analysis (EDA) techniques. This household survey is part of a research project aiming to develop an evidence base of opportunities, risks and vulnerabilities related to housing construction and resource management in incremental upgrading of informal settlements in South Africa. This dataset can be used by local practitioners and policymakers involved in decision-making for informal settlement upgrading and help them prioritise resources and upgrading interventions based on what informal dwellers need. Furthermore, this cleaned dataset could support the analysis of further South African data guiding the development of digital platforms as a real-time resource management tool or guide the enhancement of existing theoretical frameworks in the field of participatory design and co-production used by academic scholars. </p>
Assortative mating by telomere length under different environmental conditions in the brown booby, a long-lived seabird
<p class="NoteLevel11"><span>Life-history strategies covary with a suite of behavioral and physiological responses along a slow-fast continuum, known as pace-of-life-syndrome. Particularly in long-lived species, pace-of-life is expected to influence breeding strategies, making it a potentially important factor in mate choice. It has been proposed that telomere length (TL) may integrate individual physiological components and survival prospects that underlie individual differences in pace-of-life. In the brown booby (Sula leucogaster), a long-lived seabird, we investigated whether TL may indicate individual pace-of-life by examining how it relates to mitochondrial DNA copy number (mtDNAcn), corticosterone (cort) levels, and skin coloration—a condition-dependent sexual trait. Then, we tested whether there is assortative mating by TL, and whether the degree of TL similarity between partners influences an individual's likelihood of changing mates and physiological state (mtDNAcn and cort levels). Because environmental conditions may have important effects on the individual pace-of-life, the study was performed in two colonies with contrasting breeding conditions. We found that TL was positively related to mtDNAcn (but not cort levels), suggesting that individuals with shorter telomeres have reduced mitochondrial activity and aerobic capacity. TL was reflected in sexual coloration, but only in the colony with good breeding conditions. There was positive assortative mating by TL, however the degree of assortative mating was unrelated to mtDNAcn, cort levels and the probability of mate change, which greatly varied between the two colonies. Our results suggest that TL </span><span>might be an indicator of the individual pace-of-life and may influence mating patterns. </span><span>Importantly, contrasting environmental conditions </span><span>influenced the link between TL and sexual coloration and the propensity of individuals to change mate, highlighting the importance of environmental variation on breeding strategies.</span><span> </span></p>
Influence of environmental conditions on the fusion of cationic liposomes with living mammalian cells
<p>Lipid-based nanoparticles, also called vesicles or liposomes, can be used as carriers for drugs or many types of biological macromolecules including DNA and proteins. Efficiency and speed of cargo delivery are especially high for carrier vesicles that fuse with the cellular plasma membrane. This occurs for lipid mixture containing equal amounts of the cationic lipid DOTAP and a neutral lipid with an additional few percent of an aromatic substance. The fusion ability of such particles depends on lipid composition with phosphoethanolamine (PE) lipids favoring fusion and phosphatidyl-choline (PC) lipids endocytosis. Here we examined the effects of temperature, ionic strength, osmolality, and pH on fusion efficiency of cationic liposomes with Chinese hamster ovary (CHO) cells. The phase state of liposomes was analyzed by small angle neutron scattering (SANS). Our results showed that PC containing lipid membranes were organized in the lamellar phase. Here, fusion efficiency depended on buffer conditions and remained vanishingly small at physiological conditions. In contrast, SANS indicated the coexistence of very small (~ 50 nm) objects with larger, most likely lamellar structures for PE containing lipid particles. The fusion of such particles to cell membranes occurred with very high efficiency at all buffer conditions. We hypothesize that the altered phase state resulted in a highly reduced energetic barrier against fusion.</p>
Effects of a Package of Evidence-based Interventions and Implementation Strategies Based on WHO PEN for People Living With HIV and Cardio-metabolic Conditions in Lusaka, Zambia
ClinicalTrials.gov study NCT05950919. IPD Sharing: YES. Countries: 1. Publications: 1.
Effects of Substituting Sitting With Standing and Light Intensity Activity in Free-living Conditions on Glycaemia in Overweight and Obese South Asian Adults
ClinicalTrials.gov study NCT04645875. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Parameterizing the robust design in the BUGS language: lifetime carry‐over effects of environmental conditions during growth on a long‐lived bird
Open the record for dataset details and reuse information.
Data from: "Characterization of two Iberian freshwater fish transcriptomes, Squalius carolitertii and Squalius torgalensis, living in distinct environmental conditions" in Genomic Resources Notes Accepted 1 April 2015 to 31 May 2015
The advance of NGS technologies opened exciting research avenues, as for example expanding the study of the mechanisms underlying adaptation from model organisms to natural systems. We used NGS technologies to sequence 12 RNA-seq libraries, and provide the first transcriptomes of two endemic Iberian Cyprinids. The species Squalius carolitertii and S. torgalensis inhabit different regions of Portugal with distinct climate types, Atlantic in the North and Mediterranean in the South, respectively. While northern regions present mild temperatures, in southern regions fish are often under harsh temperatures and droughts. Herein, we sequenced the transcriptome from three tissues (skeletal muscle, liver and fins) in an Illumina HiSeq2000 of fish exposed to different temperatures: 18ºC (control) and 30ºC (test). Around 200 million raw reads were generated for each species, with similar number of reads per library (approximately 30 million), rendering de novo assemblies with a total of 145975 and 137303 contigs, for S. carolitertii and S. torgalensis, respectively. Gene ontology showed that around 60% of the annotated genes belonged to four biological processes and approximately 75% to two molecular functions. Besides, this study provides, for the first time, the transcriptome characterization of two endemic fish from Iberian freshwater basins, S. carolitertii and S. torgalensis, and constitutes a valuable resource for understanding environmental adaptations of Iberian Cyprinids.
Data from: Female Infidelity Is Constrained by El Niño Conditions in a Long-lived Bird
Explaining the remarkable variation in socially monogamous females' extra-pair (EP) behaviour revealed by decades of molecular paternity testing remains an important challenge. One hypothesis proposes that restrictive environmental conditions (e.g. extreme weather, food scarcity) limit females' resources and increase EP behaviour costs, forcing females to reduce EP reproductive behaviours. For the first time, we tested this hypothesis by directly quantifying within-pair and EP behaviours rather than inferring behaviour from paternity. We evaluated whether warmer sea surface temperatures depress total pre-laying reproductive behaviours, and particularly EP behaviours, in socially paired female blue-footed boobies (Sula nebouxii). Warm waters in the Eastern Pacific are associated with El Niño Southern Oscillation and lead to decreased food availability and reproductive success in this and other marine predators. With warmer waters, females decreased their neighbourhood attendance, total copulation frequency, and laying probability, suggesting that they contend with restricted resources by prioritizing self-maintenance and committing less to reproduction, sometimes abandoning the attempt altogether. Females were also less likely to participate in EP courtship and copulations, but when they did, rates of these behaviours were unaffected by water temperature. Females' neighbourhood attendance, total copulation frequency, and EP courtship probability responded to temperature differences at the between-season scale, and neighbourhood attendance and EP copulation probability were affected by within-season fluctuations. Path analysis indicated that decreased EP participation was not attributable to reduced female time available for EP activities. Together, our results suggest that immediate time and energy constraints were not the main factors limiting females' infidelity. Our study shows that El Niño conditions depress female boobies' EP participation and total reproductive activity. In addition to increasing general self-maintenance and reproductive costs, warm waters may increase costs specific to EP behaviours including divorce, reduced male parental care or pathogen exposure. Our results suggest that female boobies strategically refrained from EP behaviours to avoid these or other longer term costs, rather than being compelled by immediate constraints. This study demonstrates that current environmental conditions affect females' mating decisions, contributing to variation in EP behaviours, even in a long-lived, iteroparous species that can buffer against temporary adversity.
Data from: Linking oceanographic conditions, migratory schedules and foraging behaviour during the non‐breeding season to reproductive performance in a long‐lived seabird
1. Studies of the mechanisms underlying climate-induced population changes are critically needed to better understand and accurately predict population responses to climate change. Long-lived migratory species might be particularly vulnerable to climate change as they are constrained by different climate conditions and energetic requirements during the breeding and non-breeding seasons. Yet, most studies primarily focus on the breeding season of these species lifecycle. Environmental conditions experienced in the non-breeding season may have downstream effects on the other stages of the annual lifecycle. Not investigating such effects may potentially lead to erroneous inferences about population dynamics. 2. Combining demographic and tracking data collected between 2006 and 2013 at Kerguelen Island on a long-lived migratory seabird, the Black-Browed Albatross (Thalassarche melanophris), we investigated the links between sea surface temperature during the non-breeding season and behavioural and phenological traits (at-sea behaviour and migratory schedules) while accounting for different responses between birds of different sex and reproductive status (previously failed or successful breeders). We then explored if variation in the foraging behaviour and timing of spring migration influenced subsequent reproductive performance. 3. Our results showed that foraging activity and migratory schedules varied by both sex and reproductive status suggesting different energetic requirements and constraints among individuals. Higher sea surface temperatures during late winter, assumed to reflect poor winter conditions, were associated with an earlier departure from the wintering grounds and an extended pre-breeding period. However, an earlier spring migration and an earlier return to Kerguelen grounds were associated with a lower breeding success. 4. Our results highlighted that behaviour during some periods of the non-breeding season, particularly towards the end of the wintering period and the pre-breeding period had a significant effect on the subsequent reproductive success. Therefore, caution needs to be given to all stages of the annual cycle when predicting the influence of climate on population dynamics.
FIG. 2. Galapa Huber, 2000, live specimens. A–D. G in Thriving in dry conditions: on the Neotropical spider genus Galapa (Araneae: Pholcidae)
FIG. 2. Galapa Huber, 2000, live specimens. A–D. G. murphyi Huber sp. n.; male and female with egg sac from W of Cañas; female with egg-sac from near Playa Iguanita, and female in web (in glass vial) from near Playa Iguanita. E–F. G. gabito Huber sp. n.; male and female with egg sac from Santa Marta. G–H. G. spiniphila Huber, 2020; male and female with egg sac from S of Riohacha. I. G. spiniphila; male from ESE of Pueblo Bello.
Data from: Regulation of thermal acclimation varies between generations of the short-lived mosquitofish (Gambusia holbrooki) that developed in different environmental conditions
1. Environmental variability and perturbations can influence population persistence. It is therefore important to understand whether and how animals can compensate for environmental variability, and thereby increase resilience of natural populations. Evolutionary theory predicts that in fluctuating environments selection should favour developmental modifiers that reduce phenotypic expression of genetic variation. The expected result is that phenotypes are buffered from environmental variation across generations. 2. Our aim was to determine whether phenotypes of mosquitofish (Gambusia holbrooki) remain stable across generations in which individuals were born into different thermal environments. We predicted that the spring generation (cool environment) would acclimate by increasing the concentration of regulatory transcription factor mRNA and activities of rate-limiting enzymes (hierarchical regulation) to compensate for the negative thermodynamic effects of lower temperatures on metabolic and locomotor performance. In contrast, the summer-born generation (warm environment) would show less capacity for acclimation and hierarchical regulation. 4. We show that fish from both generations acclimated, but that there were significant differences in the phenotypic consequences of acclimation. The overall result was that sprint performance, metabolic scope, and the activities of cyctochrome c oxidase and lactate dehydrogenase were buffered from environmental change, and did not differ between spring and summer fish at their natural water temperatures of 15oC and 25oC, respectively. However, there were differences between generations in sustained swimming performance and citrate synthase activity. 5. We used metabolic control analysis to show that modes of regulation of metabolic scope and locomotor performance differed between generations. Spring fish showed primarily hierarchical regulation, but regulation in summer fish relied to a lesser extent on rate-limiting enzymes and transcription factors. 6. We suggest that developmental modifiers are favoured in fluctuating environments to maximise phenotypic fitness of each generation. We show that the interaction between developmental and reversible acclimation can render physiological performance of a natural population independent from climate variation.
Closing the Loop in Adults With Type 1 Diabetes Under Free Living Conditions
ClinicalTrials.gov study NCT04055480. IPD Sharing: YES. Countries: 3. Publications: 1.
Closing the Loop in Adults With Type 1 Diabetes Under Free Living Conditions (AP@Home04_Phase 4)
ClinicalTrials.gov study NCT05257460. IPD Sharing: YES. Countries: 1. Publications: 2.
The Impact of Light Conditions on the Efficacy of Multifocal Intraocular Lens Implantation in Activities of Daily Living
ClinicalTrials.gov study NCT05359380. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Closing the Loop in Adults With Sub-optimally Controlled Type 1 Diabetes Under Free Living Conditions
ClinicalTrials.gov study NCT01961622. IPD Sharing: Not stated. Countries: 3. Publications: 5.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.