Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
62
datasets available to search
ShareScore release 0.9.0
Dataset results
62 results for “Locus of Control”
Data from: Carotenoid pigmentation in salmon: Variation in expression at BCO2-l locus controls a key fitness trait affecting red colouration
Carotenoids are primarily responsible for the characteristic red flesh colouration of salmon. Flesh colouration is an economically and evolutionarily significant trait that varies inter- and intra-specifically, yet the underlying genetic mechanism is unknown. Chinook salmon (Oncorhynchus tshawytscha) represent an ideal system to study carotenoid variation as, unlike other salmonids, they exhibit extreme differences in carotenoid utilization due to genetic polymorphisms. Here, we crossed populations of Chinook salmon with fixed differences in flesh colouration (red vs. white) for a genome-wide association study (GWAS) to identify loci associated with pigmentation. Here, the beta-carotene oxygenase 2-like (BCO2-l) gene was significantly associated with flesh colour, with the most significant SNP explaining 66% of the variation in colour. BCO2 gene disruption is linked to carotenoid accumulation in other taxa, therefore we hypothesize that an ancestral mutation partially disrupting BCO2-l activity (i.e., hypomorphic mutation) allowed the deposition and accumulation of carotenoids within Salmonidae. Indeed, we found elevated transcript levels of BCO2-l in white Chinook salmon relative to red. The long-standing mystery of why salmon are red, while no other fishes are, is thus likely explained by a hypomorphic mutation in the proto-salmonid at the time of divergence of red-fleshed salmonid genera (~30 MYA).
The Sensorimotor Locus of Balance Control in Elderly Gait
ClinicalTrials.gov study NCT03341728. IPD Sharing: NO. Countries: 1. Publications: 5.
Data from: Carotenoid pigmentation in salmon: Variation in expression at BCO2-l locus controls a key fitness trait affecting red colouration
Open the record for dataset details and reuse information.
A major locus controls a biologically active pheromone component in Heliconius melpomene
<p>Understanding the production, response, and genetics of signals used in mate choice can inform our understanding of the evolution of both intraspecific mate choice and reproductive isolation. Sex pheromones are important for courtship and mate choice in many insects, but we know relatively little of their role in butterflies. The butterfly <i>Heliconius</i> <i>melpomene</i> uses a complex blend of wing androconial compounds during courtship. Electroantennography in <i>H. melpomene </i>and its close relative <i>H. cydno</i> showed that responses to androconial extracts were not species-specific. Females of both species responded equally strongly to<i> </i>extracts of both species, suggesting conservation of peripheral nervous system elements across the two species. Individual blend components provoked little to no response, with the exception of octadecanal, a major component of the <i>H. melpomene </i>blend. Supplementing octadecanal on the wings of octadecanal-rich <i>H. melpomene </i>males led to an increase in the time until mating, demonstrating the bioactivity of octadecanal in <i>Heliconius</i>. Using quantitative trait locus (QTL) mapping, we identified a single locus on chromosome 20 responsible for 41% of the parental species' difference in octadecanal production. This QTL does not overlap with any of the major wing color or mate choice loci, nor does it overlap with known regions of elevated or reduced <i>F</i><sub>ST</sub>. A set of 16 candidate fatty acid biosynthesis genes lies underneath the QTL. Pheromones in <i>Heliconius </i>carry information relevant for mate choice and are under simple genetic control, suggesting they could be important during speciation.</p>
Locus of control, Moral Competence, Job Satisfaction and Unethical Workplace Behaviors
<p><span>From the Causal Reasoning Model of Counterproductive Work behaviors, unethical workplace behaviors are a function of cognitive processes. Organizations cannot effectively prevent unethical employee behaviors without knowledge of cognitive antecedents of such behaviors. Towards this end, this dataset focuses on some of the cognitive variables that might play a role in unethical workplace behavior. The data specifically focuses on the facets of locus of control (LOC), moral potency, job satisfaction, and counterproductive work behavior. The data shows that job satisfaction mediates the negative effects of both internal and external LOC on counterproductive work behavior. Moral potency seems to strengthen the negative effects of internal LOC and buffers against the positive effects of facets of external LOC on counterproductive work behavior. </span></p> <p><span>The resulting paper is under consideration for publication in the journal of International Journal of Applied Positive Psychology. </span></p>
A major locus controls a biologically active pheromone component in Heliconius melpomene
Open the record for dataset details and reuse information.
Data from: Excessive use of WeChat, social interaction and locus of control among college students in China
In China, the number of college students using mobile phone based messaging and social networking applications like WeChat is increasing rapidly. However, there has been minimal research into the addictive nature of these applications and the psychological characteristics associate with their excessive use. There is also no published scale available for assessing excessive use of WeChat and similar applications. In the current study, we collected data from 1,245 college students in China (715 females) and developed the WeChat Excessive Use Scale (WEUS). We then assessed the relationship between excessive use of WeChat and excessive use of a social networking application-Weibo, problematic use of mobile phones, external locus of control, and social interaction skills. Our 10-item scale featured three factors, namely- "mood modification," "salience" and ''conflict"- critical factors in assessing different forms of addiction. The WEUS was found to be a reliable instrument in assessing excessive use of WeChat as it showed good internal consistency and correlated with other measures of problematic use social networking and mobile phone addiction. Our results showed that excessive users of WeChat are more likely to excessively use Weibo than they are to problematically use mobile phones. Our study also showed that greater excessive use of WeChat is associated with higher external locus of control and greater online social interaction skills. These results reveal that WeChat has unique and strong appeal among college students in China. Further, practitioners should consider dealing with malleable factors like locus of control and real life social skills in treating people with problematic messaging and social networking.
[Data from:] A butterfly egg-killing hypersensitive response in Brassica nigra is controlled by a single locus, PEK, containing a cluster of TIR-NBS-LRR receptor genes
<p>Genetic mapping of a HR-like cell death induced by <em>Pieris </em>spp. butterfly eggs in <em>Brassica nigra.</em></p>
Supplementary material for Duruflé et al. "Natural variation in chalcone isomerase defines a major locus controlling growth variation between Populus nigra populations"
Open the record for dataset details and reuse information.
Spatial Transcriptomics data (GeoMx) of locus coeruleus dopamine cells in control and PD subjects
<p>The repository includes Spatial Transcriptomic datasets generated by Nanostring GeoMx (Hu WTA) analysis of locus coeruleus TH+ cells from Controls (n=9), early Parkinsons Disease (ePD, n=8) and late Parkinsons Disease (lPD, n=2). A total 39 Regions of Interest were analysed. The raw and processed counts and metadata are provided as an R Seurat object (geomx_vila_thmask.rds). The scripts used for low level data processing are described in https://github.com/zchatt/ASAP-SpatialTranscriptomics/blob/main/geomx/lowlevel/README.md.</p> <p>Tissue samples from pathologically confirmed stage IV Lewy body PD (early-PD), stage VI Lewy body PD (late-PD)(Braak, Del Tredici et al. 2003) and controls without the neurological or neuropathological disease were obtained from the Sydney Brain Bank. The study was approved by the University of Sydney Human Research Ethics Committee (2021/845). All cases with PD were levodopa-responsive and fulfilled the UK Brain Bank Clinical Criteria for a diagnosis of clinical PD (Hughes, Ben-Shlomo et al. 1992) with no other neurodegenerative conditions. </p> <p>Cells were not extracted. Tissue sections were cut from FFPE blocks of post-mortem human midbrains at 6µm on a rotary microtome (HistoCore MULTICUT, Leica Biosystems) and mounted on Series 2 adhesive microscope slides (Trajan Scientific Medical, AU) for processing for spatial trranscriptomics. To remove the paraffin, slides were incubated in the oven at 60°C for 1hr and then submerged in HistoChoice Clearing Agent (Sigma-Aldrich, H2779) for 2x7mins, followed by rehydration in decreasing ethanol concentrations (100% ethanol for 2x3mins, 95% ethanol for 3mins, 70% ethanol for 3mins) and distilled H2O for 3mins. </p> <p>Tissue sections were immunohistochemically stained for tyrosine hydroxylase and Regions of Interest (ROIs) processed following Nanostring GeoMx® Digital Spatial Profiler using the manufacturer’s instructions. Libraries were sequenced on Illumina Novaseq 6000 platform using NovaSeq SP 100 cycle kit (XP workflow, 27-8-8-27).</p> <p>This research was funded in whole or in part by Aligning Science Across Parkinson’s (ASAP-020505) through the Michael J. Fox Foundation for Parkinson’s Research (MJFF). For the purpose of open access, the author has applied a CC BY 4.0 public copyright license to all Author Accepted Manuscripts arising from this submission.</p>
Data from: Hybrid sterility locus on Chromosome X controls meiotic recombination rate in mouse
Open the record for dataset details and reuse information.
Data from: Excessive use of WeChat, social interaction and locus of control among college students in China
Open the record for dataset details and reuse information.
Locus-specific paramutation in Zea mays is maintained by a chromodomain helicase DNA-binding 3 protein controlling development and male gametophyte function
GEO Series GSE158990. Zea mays. 5 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The DMD locus harbours multiple long non-coding RNAs which orchestrate and control transcription of muscle dystrophin mRNA isoforms
GEO Series GSE27068. Homo sapiens. 8 samples. Type: Expression profiling by genome tiling array; Non-coding RNA profiling by genome tiling array.
Structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
GEO Series GSE182224. Pan troglodytes; Homo sapiens. 71 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Analysis of the origin of stenospermocarpy under the control of the major seedlessness locus in grapevine
GEO Series GSE107014. Vitis vinifera. 6 samples. Type: Expression profiling by high throughput sequencing.
PGC reversion to pluripotency involves erasure of DNA methylation from imprinting control centers followed by locus-specific re-methylation
GEO Series GSE69354. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
A b-catenin-TCF-sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer
GEO Series GSE171910. Homo sapiens. 34 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Cell-specific and shared regulatory elements control a multi-gene locus active in mammary and salivary glands
GEO Series GSE231441. Mus musculus. 167 samples. Type: Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Cell-specific and spatio-temporal controls of the estrogen-responsive trefoil factor (TFF) locus activity
GEO Series GSE32132. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by genome tiling array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.