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Dataset results
37 results for “MAPT”
Literature Review 13/02/2018: Genetic risk of Parkinson's disease dementia due to APOE4 or MAPT
<p>Literature review assessing genetic risk of dementia due to <em>APOE4</em> or <em>MAPT </em>in Parkinson's disease, performed on the 13<sup>th</sup> February 2018. All studies had to fulfil three<em> a priori </em>inclusion criteria:</p> <p>1) Case control studies using clinically diagnosed or pathologically confirmed PD and PDD.</p> <p>2) Time between motor diagnosis and experimental assessment could be defined or estimated.</p> <p>3) Genotype information supplied, allowing the odds ratio (OR) and confidence intervals (CI) to be calculated that aligned with the genotype categories used in this work.</p> <p>For <em>MAPT</em>, a PubMed search for the term “<em>MAPT Parkinson’s dementia</em>” identified 105 potential matches, of which 9 met the inclusion criteria. For <em>APOE4</em>, a PubMed search for the term “<em>APOE Parkinson’s dementia</em>” identified 188 potential matches, of which 19 met the inclusion criteria. Note, the review includes several publications arising from the CamPaIGN cohort; As we were interested in genetic risk as a function of time from diagnosis, we included each unique study time-point. </p>
Cancer-specific association between Tau (MAPT) and cellular pathways, clinical outcome, and drug response
<p>To bring new evidence that Tau represents a key protein in cancer, we present an <em>in silico</em> pan-cancer analysis of <em>MAPT</em> transcriptomic profile in over 10000 clinical samples and over 1300 pre-clinical samples provided by the TCGA and the DEPMAP datasets respectively.</p>
The EFFECTS of GAMBIR CATECHIN (UNCARIA GAMBIR ROXB) SUPPLEMENTATION on COGNITIVE FUNCTION, EXPRESSION of APP, MAPT, BDNF, IL-10, TGF-Β GENES, and PLASMA MDA LEVELS in the ELDERLY.
ClinicalTrials.gov study NCT06604390. IPD Sharing: NO. Countries: 2. Publications: 4.
Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations
ClinicalTrials.gov study NCT02676843. IPD Sharing: YES. Countries: 1. Publications: 0.
Characterizing the clinical features and atrophy patterns of MAPT-related frontotemporal dementia with disease progression modelling (Supplementary Data)
Open the record for dataset details and reuse information.
MAPT expression is regulated by long-range interactions with cis-regulatory elements [ChIP-seq]
GEO Series GSE228116. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
MAPT expression is mediated by long-range interactions with cis-regulatory elements [scMultiomics]
GEO Series GSE228120. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
MAPT expression is mediated by long-range interactions with cis-regulatory elements [RNA-seq]
GEO Series GSE228115. Homo sapiens. 384 samples. Type: Expression profiling by high throughput sequencing.
Glutamatergic dysfunction precedes neuron loss in cerebral organoids with MAPT mutations
GEO Series GSE171345. Homo sapiens. 276 samples. Type: Expression profiling by high throughput sequencing.
Identification and Characterization of a MAPT-targeting Locked Nucleic Acid Antisense Oligonucleotide Therapeutic for Tauopathies I
GEO Series GSE204930. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
MAPT expression is mediated by long-range interactions with cis-regulatory elements [HiC and Capture-C]
GEO Series GSE228118. Homo sapiens. 21 samples. Type: Other.
Identification and Characterization of a MAPT-targeting Locked Nucleic Acid Antisense Oligonucleotide Therapeutic for Tauopathies II
GEO Series GSE204931. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
GEO Series GSE230450. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT
GEO Series GSE250316. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Glutamatergic dysfunction precedes neuron loss in cerebral organoids with MAPT mutations [bulk RNA-Seq]
GEO Series GSE171343. Homo sapiens. 240 samples. Type: Expression profiling by high throughput sequencing.
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
GEO Series GSE230520. Homo sapiens. 61 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing.
Nuclear speckle specific hnRNP DL loss lead to aging associated-cognitive decline by modulating MAPT alternative splicing
GEO Series GSE169281. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Induced human forebrain neurons overexpressing MAPT demonstrate chromatin structure alterations
GEO Series GSE97409. Homo sapiens. 36 samples. Type: Other.
MAPT Haploid H1b and the Damage of BBB in Dorsal Medulla Oblongata and Autonomic Dysfunction in PD
ClinicalTrials.gov study NCT05471713. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of ARO-MAPT-SC in Healthy Subjects and Subjects With Early Alzheimer's Disease
ClinicalTrials.gov study NCT07221344. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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