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ShareScore release 0.9.0
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42 results for “MERS-CoV”
Safety, Tolerability and Immunogenicity of INO-4700 for MERS-CoV in Healthy Volunteers
ClinicalTrials.gov study NCT04588428. IPD Sharing: YES. Countries: 3. Publications: 1.
Data from: Association between severity of MERS-CoV infection and incubation period
We analyzed data for 170 patients in South Korea who had laboratory-confirmed infection with Middle East respiratory syndrome coronavirus. A longer incubation period was associated with a reduction in the risk for death (adjusted odds ratio/1-day increase in incubation period 0.83, 95% credibility interval 0.68–1.03).
Innate and adaptive immune genes associated with MERS-CoV infection in dromedaries
<p>The recent SARS-CoV-2 pandemic has refocused attention to the betacoronaviruses, only eight years after the emergence of another zoonotic betacoronavirus, the Middle East respiratory syndrome coronavirus (MERS-CoV). While the wild source of SARS-CoV-2 may be disputed, for MERS-CoV, dromedaries are considered as source of zoonotic human infections. Testing 100 immune- response genes in 121 dromedaries from United Arab Emirates (UAE) for potential association with present MERS-CoV infection, we identified candidate genes with important functions in the adaptive, MHC-class I (HLA-A-24-like) and II (HLA-DPB1-like), and innate immune response (PTPN4, MAGOHB), and in cilia coating the respiratory tract (DNAH7). </p>
A Clinical Trial to Determine the Safety and Immunogenicity of Healthy Candidate MERS-CoV Vaccine (MERS002)
ClinicalTrials.gov study NCT04170829. IPD Sharing: NO. Countries: 1. Publications: 1.
MERS-CoV Infection tReated With A Combination of Lopinavir /Ritonavir and Interferon Beta-1b
ClinicalTrials.gov study NCT02845843. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Safety and Immunogenicity of a Candidate MERS-CoV Vaccine (MERS001)
ClinicalTrials.gov study NCT03399578. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Association between severity of MERS-CoV infection and incubation period
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Innate and adaptive immune genes associated with MERS-CoV infection in dromedaries
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Selectomic and Evolvability Analyses of the Highly Pathogenic Betacoronaviruses SARS-CoV-2, SARS-CoV, and MERS-CoV
<p>SARS-CoV-2, the causative agent of COVID-19, is widespread in several countries around the world following its late 2019 emergence in humans. We determined the SARS-CoV-2 selectome by calculating rates of pervasive and episodic diversifying selection for every amino acid coding position in the SARS-CoV-2 genome. To provide context for evolutionary dynamics of a highly pathogenic betacoronavirus following a zoonotic spillover into human hosts, we also determined the selectomes of SARS-CoV and MERS-CoV, and performed evolvability calculations for SARS-CoV-2 based on SARS-CoV. These findings provide a comprehensive view of zoonotic, highly pathogenic betacoronavirus evolutionary dynamics that can be directly applied to diagnostic assay and vaccine design for SARS-CoV-2.</p>
The time between symptom onset and various clinical outcomes: A statistical analysis of MERS-CoV patients in Saudi Arabia
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Primary human microvascular endothelial cell transcriptome response to wild type MERS-CoV (icMERS-CoV EMC2012), MMVE003
GEO Series GSE100509. Homo sapiens. 50 samples. Type: Expression profiling by array.
Primary human microvascular endothelial cell transcriptome response to wild type Mers-CoV (icMERS-CoV EMC2012), MHAE002
GEO Series GSE86530. Homo sapiens. 50 samples. Type: Expression profiling by array.
Transcriptional responses of Middle East respiratory syndrome coronavirus (MERS-CoV) in marmosets
GEO Series GSE55023. Callithrix jacchus. 43 samples. Type: Expression profiling by high throughput sequencing.
Primary human microvascular endothelial cell transcriptome (mRNA) response to a wild type MERS-CoV (icMERS-CoV EMC2012)
GEO Series GSE79218. Homo sapiens. 49 samples. Type: Expression profiling by array.
Primary human fibroblast transcriptome (mRNA) response to wild type MERS-CoV (icMERS)
GEO Series GSE79458. Homo sapiens. 50 samples. Type: Expression profiling by array.
Primary human fibroblasts transcriptome response to a wild type Mers-CoV (icMERS-CoV), MFB003
GEO Series GSE100496. Homo sapiens. 50 samples. Type: Expression profiling by array.
Cytokine stimulation systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates.
GEO Series GSE56677. Homo sapiens. 33 samples. Type: Expression profiling by array.
Primary human dendritic cell transcriptome response to a wild type MERS-CoV (icMERS)
GEO Series GSE79172. Homo sapiens. 29 samples. Type: Expression profiling by array.
Relative timing of type I interferon response and virus replication determines disease outcome during MERS-CoV infection
GEO Series GSE131936. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Primary human microvascular endothelial cell transcriptome (microRNA) response to wild type MERS-CoV (icMERS-CoV EMC2012)
GEO Series GSE79216. Homo sapiens. 14 samples. Type: Non-coding RNA profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.