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89 results for “MIC”
OMAP-23: Organ Mapping Antibody Panel (OMAP) for Multiplexed Antibody-Based Imaging of vermiform appendix (FFPE) with MICS on MACSima
<p><strong>Description</strong></p> <p> OMAP-23 was designed for MICS (MACSima imaging cyclic staining) imaging of FFPE human vermiform appendix sample. Tissue fixation and antigen retrieval is described in (<a href="https://www.biorxiv.org/content/biorxiv/early/2023/11/07/2023.10.27.564191.full.pdf">Spatial protein and RNA analysis on the same tissue section using MICS technology</a>). The MACSima technology is described in detail in the following publication (<a href="https://doi.org/10.1038/s41598-022-05841-4">MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors</a>). All, antibodies in this panel are recombinant antibodies with a mutated human IgG1 constant region, removing Fc receptor binding capacity of human IgG1, eliminating the need for additional blocking steps and reducing non-specific binding. The use of human IgG1 recombinant antibodies allows for the addition of uncoupled monoclonal antibodies from other species followed by a fluorescence labelled secondary reagent specific for the species of the monoclonal antibody. The multiplex system has been described already for OMAP-10 and OMAP-21. A new dye VioB515 is used for one reagents. The fluorescence is removed by cleavage. The panel contains 28 antibodies and the nuclear marker DAPI for image alignment and nuclear segmentation. This OMAP provides a spatial context for six anatomical structures and most cell types present in the vermiform appendix (link to ASCT+B table added). OMAP-23 follows OMAP-21, with fewer antibodies but adding antibodies for non-immune cells.</p> <p>All reagents are from Miltenyi Biotec and have been rigorously tested through an internal quality control system to have minimal variation between lots. For this reason, lot information is not included in this table. Analysis was performed by an accompanied software package MACSIQ View Analysis also described in the MACSima publication (<a href="https://doi.org/10.1038/s41598-022-05841-4">https://doi.org/10.1038/s41598-022-05841-4</a>). The MACSima system is continuously evolving, this is the third OMAP for the MACSima system. A representative dataset created using OMAP-23 can be found here 10.5281/zenodo.14008816 .The AVRs for the dataset can be found here (to be added).</p>
MIC dataset from 20210705
<p>This is the raw data from the MIC experiment of 20210705 with e.coli and ciprofloxacyn.</p> <p>To process with the package <a href="https://github.com/BaroudLab/anchor-droplet-chip">anchor-droplet-chip</a></p>
Dataset: The Singing Machine Company, Inc. (MICS) Stock Performance
This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.
OMAP-21: Organ Mapping Antibody Panel (OMAP) for Multiplexed Antibody-Based Imaging of Human Palatine Tonsil with MICS on MACSima 1.5
<p>OMAP-21 was designed for MICS (MACSima imaging cyclic staining) imaging of FFPE human tonsil samples. Tissue fixation and antigen retrieval is described in (<a href="https://www.biorxiv.org/content/biorxiv/early/2023/11/07/2023.10.27.564191.full.pdf">Spatial protein and RNA analysis on the same tissue section using MICS technology</a>). The MACSima technology is described in detail in the following publication (<a href="https://doi.org/10.1038/s41598-022-05841-4">MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors</a>). Most, but not all, antibodies in this panel are recombinant antibodies with a mutated human IgG1 constant region. The described mutation removes the Fc receptor binding capacity of human IgG1, eliminating the need for additional blocking steps and reducing non-specific binding of human antibodies on human tissues. Highly multiplexed imaging is achieved through cycles of immunolabeling with FITC, PE, and APC conjugated antibodies and photobleaching to eliminate fluorescence signal between imaging cycles. The panel contains 47 antibodies and the nuclear marker DAPI for image alignment and nuclear segmentation. This OMAP provides a spatial context for all anatomical structures and most cell types present in the human palatine tonsil. OMAP-21 follows closely OMAP-1 described for human lymph nodes (<a href="https://cdn.humanatlas.io/hra-releases/v1.4/docs/omap/omap-1-human-lymph-node-ibex.html">omap-1-human-lymph-node-ibex</a>) and OMAP-10 (<a href="https://cdn.humanatlas.io/hra-releases/v1.4/docs/omap/omap-10-palatine-tonsil-macsima.html">omap-10-palatine-tonsil-macsima</a>).</p> <p>All reagents were obtained from Miltenyi Biotec and have been rigorously tested through an internal quality control system to have minimal variation between lots. For this reason, lot information is not included in this table. Analysis was performed by an accompanied software package MACSIQ View Analysis also described in the MACSima publication (<a href="https://doi.org/10.1038/s41598-022-05841-4">https://doi.org/10.1038/s41598-022-05841-4</a>). The result of the analysis is included in the uploaded dataset. In brief, the software processes the raw images of the MACSima run, generates stitched images, and then allows downstream analysis including cell segmentation, cell gating, data normalization, dimension reduction plots (tSNE, UMAP), heat maps, distance analyses and cluster analyses, all of which are interactively linked together. The MACSima system is continuously evolving, this is the second OMAP for the MACSima system. A representative dataset created using OMAP-21 can be found here:<a href="https://doi.org/10.5281/zenodo.7875937"> </a><strong> 10.5281/zenodo.11281609 .</strong></p>
Linked collectors and determiners for: Colección de Hongos del Herbario de la Universidad de La Laguna: TFC Mic.
Natural history specimen data linked to collectors and determiners held within, "Colección de Hongos del Herbario de la Universidad de La Laguna: TFC Mic". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/71e48eba-f762-11e1-a439-00145eb45e9a">https://bionomia.net/dataset/71e48eba-f762-11e1-a439-00145eb45e9a</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/71e48eba-f762-11e1-a439-00145eb45e9a">https://gbif.org/dataset/71e48eba-f762-11e1-a439-00145eb45e9a</a>. Formatted as a Frictionless Data package.
Survey Comics and Education. ICOn MICs CA19119 Validation 2021
<p>Survey "Comics and education" of the WG5 of the COST ICOnMICs action. Presentation at Teaching with comics Congress, Valencia. Presentation of the validated survey. Results (anonymous) of the validation by the members of the working group 5.</p> <p>More information on: <a href="https://iconmics.hypotheses.org/2140">https://iconmics.hypotheses.org/2140</a></p>
MIC-MAQ plugin training images
<p>*MIC-MAQ plugin training images*</p> <p>We provide images to train segmentation on fluorescence and brightfield images. </p> <p> </p> <p>For fluorescence:</p> <p>- QIBC dataset for nuclei segmentation and quantification (https://zenodo.org/record/8014997). The 3 channels of each field of view are saved in independant files: C1 (protein of interest, spots detection), C2 (EdU for quantification), C3 (nuclei segmentation).</p> <p>- Cyto dataset for nuclei and cell segmentation. The two fields of view are saved in a single LIF file that contains Z stack. </p> <p> </p> <p>For Brightfield:</p> <p>- Yeast dataset for cell segmentation</p>
"I'm something of an untrained, unofficial cultural anthropologist myself. Ihave a business interviewing people to capture their personal histories. I'm always interested how people fit into their world and how they affect their world. I'm a graphic designer who works in the same building as the printing presses that I recorded. Iwalk past the presses every day on my way to talk to the folks in the prepress department. I'm on friendly but not drinking terms with the pressmen. I'm a friend with the prepress manager. Three Heidelberg presses are installed side by side in an open warehouse-like room. The presses are about twenty feet long and about five feet high. With their series of four humps or mounds where each printing cylinder is located, the presses remind one of giant, gray, mechanical caterpillars. Each press has a cyan cylinder, a magenta cylinder, a yellow cylinder and a black cylinder – so the humps are brightly colored. The presses are well lit by banks of fluorescent lights hanging from the ceiling over each press. When you walk into the press room you hear the sound of rock music blaring from a boom box radio mixed with the general din of the presses. It is only when you walk up to a press like Idid for the recordings that you really start to hear the individual strains of clicking, clacking and mechanical, syncopated chattering. When I made my recordings I was intrigued by the subtle variations in the sounds produced by these machines that aren't apparent when you first walk through the door. The pressmen were kind enough to allow me to walk right up to the presses and poke my microphone quite close to the rotating press cylinders. Iuse a Danish Pro Audio microphone about the size of a pencil eraser. An extremely sensitive mic with the capacity for capturing loud sounds such as the presses up close. Rotating the mic to one side or the other focused on the unique sounds coming from one cylinder or the other." [Kevin/KMerrell]18 in Collecting Sounds. Online Sharing of Field Recordings as Cultural Practice
"I'm something of an untrained, unofficial cultural anthropologist myself. Ihave a business interviewing people to capture their personal histories. I'm always interested how people fit into their world and how they affect their world. I'm a graphic designer who works in the same building as the printing presses that I recorded. Iwalk past the presses every day on my way to talk to the folks in the prepress department. I'm on friendly but not drinking terms with the pressmen. I'm a friend with the prepress manager. Three Heidelberg presses are installed side by side in an open warehouse-like room. The presses are about twenty feet long and about five feet high. With their series of four humps or mounds where each printing cylinder is located, the presses remind one of giant, gray, mechanical caterpillars. Each press has a cyan cylinder, a magenta cylinder, a yellow cylinder and a black cylinder – so the humps are brightly colored. The presses are well lit by banks of fluorescent lights hanging from the ceiling over each press. When you walk into the press room you hear the sound of rock music blaring from a boom box radio mixed with the general din of the presses. It is only when you walk up to a press like Idid for the recordings that you really start to hear the individual strains of clicking, clacking and mechanical, syncopated chattering. When I made my recordings I was intrigued by the subtle variations in the sounds produced by these machines that aren't apparent when you first walk through the door. The pressmen were kind enough to allow me to walk right up to the presses and poke my microphone quite close to the rotating press cylinders. Iuse a Danish Pro Audio microphone about the size of a pencil eraser. An extremely sensitive mic with the capacity for capturing loud sounds such as the presses up close. Rotating the mic to one side or the other focused on the unique sounds coming from one cylinder or the other." [Kevin/KMerrell]18
Schema di riferimento geografico amministrativo dei comuni italiani della base di dati MIC su RaDISAN flusso unico, costruito partendo da Comuni_Italiani_ISTAT_30_06_2023 di ISTAT
<p><strong>Comuni_Italiani_ISTAT_MIC </strong>rappresenta l'anagrafica più recente dei comuni italiani è dovrà integrare la georeferenziazione della base di dati MIC su RaDISAN flusso unico. ISTAT fa un aggiornamento semestrale (<a href="https://www.istat.it/it/archivio/6789">https://www.istat.it/it/archivio/6789</a>) delle unità amministrative territoriali.</p>
Urcior mic
Urcior mic dacic, cu o toartă, modelat la roata olarului, din pastă fină și culoare cenușie, datat în sec. I p. Chr. Vasul a fost ornamentat cu linii lustruite verticale pe jumătatea sa superioară. Recipientul era destinat servirii lichidelor și a fost descoperit într-o locuință dacică de Șimleu Silvaniei-Cetate. Source: Objaverse 1.0 / Sketchfab
Genomics polymorphisms of Staphylococcus aureus strain NCTC 8325 in the lab stock maintained at TUM (WT), after 30 passes in BHI media (D) and after 30 passes detecting 4 -fold MIC increase to isocyanide -code I16- 3 biological replicates (A,B,C), and 3 independent colonies sequenced per replicate at the end of the experiment.
<p>Genomics polymorphisms of Staphylococcus aureus strain NCTC 8325 in the lab stock maintained at TUM (WT), after 30 passes in BHI media (D) and after 30 passes detecting 4 -fold MIC increase to isocyanide -code I16- 3 biological replicates (A,B,C), and 3 independent colonies sequenced per replicate at the end of the experiment. Determined from Illumina shotgun genomic sequencing datasets, mapping and analyses vs the reference genome of the strain https://www.ncbi.nlm.nih.gov/nuccore/NC_007795.1/</p>
MIC dataset for Anisaxin WP5 Task 2
<p>Data from an MIC experiment using Edwardsiella and othe bacteria with anisaxin</p>
Determination of Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC)
<p>Video demonstrating the protocol for determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of essential oils using the micro-dilution method. Training video elaborated within the ArtiSaneFood project.</p>
Data for AU Mic Flares Observed with HST/COS
<p>Data products and tables affiliated with "AU Microscopii in the FUV: Observations in Quiescence, During Flares, and Implications for AU Mic b and c" (Feinstein et al. 2022). This directory contains the following data products:</p> <ul> <li><strong>A demonstration Jupyter notebook on how to create the SED for AU Mic (</strong>panchromatic_spectrum_demo.ipynb<strong>) and all affiliated spectra and errors</strong> <ul> <li>X-ray -- XMM-Newton (xmm_newton_spectrum.npy)</li> <li>Differential Emission Measurement flux (au_mic_dem_quiescent_spectrum.fits)</li> <li>FUV -- FUSE (fuse_spectra.npy)</li> <li>FUV -- HST/COS (hst_cos_quiescent_spectrum.txt)</li> <li>NUV -- IUE (iue_spectra.npy)</li> <li>Optical -- HARPS-N (harps_spectra.npy)</li> <li>Optical/NIR -- PHOENIX model (phoenix_grid_3700_4.5_0.0.npy)</li> </ul> </li> <li><strong>A table of 176 measured emission lines from the HST/COS spectra of AU Mic (</strong>au_mic_full_emission_line_list.txt<strong>)</strong></li> <li><strong>The modeled transmission spectra for AU Mic b and c and a demonstration Jupyter notebook for how to read in the files</strong> (tp_profile_demo.ipynb): <ul> <li>Disequilibrium model for AU Mic b (au_mic_b_disequil_profile.dat)</li> <li>Disequilibrium model for AU Mic c (au_mic_c_disequil_profile.dat)</li> <li>Equilibrium model for AU Mic b (au_mic_b_equil_profile.dat)</li> <li>Equilibrium model for AU Mic c (au_mic_c_equil_profile.dat)</li> </ul> </li> </ul>
Urcior mic
Urcior mic dacic, cu o toartă, modelat la roata olarului, din pastă fină și culoare cenușie, datat în sec. I a. Chr. Vasul a fost ornamentat cu motive geometrice lustruite pe jumătatea sa superioară. Recipientul era destinat servirii lichidelor și a fost descoperit într-o groapă dacică de Șimleu Silvaniei-Observator. Source: Objaverse 1.0 / Sketchfab
Encuesta Cómics y Educación, Survey Cómics and Education iCOn-MICs 2024
<p><strong>PERFIL DE LA INVESTIGACIÓN EDUCATIVA SOBRE EL CÓMIC EN PORTUGUÉS Y EN ESPAÑOL</strong></p> <p>-Estos datos forman parte de la investigación "Cómics y Educación" del Grupo de Trabajo 5 del proyecto COST Investigación sobre el Cómic y la Novela Gráfica en el Aula Cultural Ibérica iCOn-MICs.</p> <p><br>-These data are part of the research ‘Comics and Education’ of Working Group 5 of the COST project Comics and Graphic Novel Research in the Iberian Cultural Classroom iCOn-MICs.</p> <p><br>-Ces données font partie de la recherche « Comics and Education » du groupe de travail 5 du projet COST Comics and Graphic Novel Research in the Iberian Cultural Classroom iCOn-MICs.</p> <p><br>-Estes dados fazem parte da investigação “Banda Desenhada e Educação” do Grupo de Trabalho 5 do projeto COST Investigação em Banda Desenhada e Novelas Gráficas na Aula Cultural Ibérica iCOn-MICs.</p>
Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Mult
ClinicalTrials.gov study NCT02852902. IPD Sharing: YES. Countries: 1. Publications: 3.
Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313
ClinicalTrials.gov study NCT03184428. IPD Sharing: YES. Countries: 1. Publications: 17.
Lexicon from the "Mics in the ears" experimental procedure Lexique issu du dispositif expérimental « Des micros dans les oreilles »
<p>« Mics in the Ears » binaural experiment in Cairo (Egypt): Vincent Battesti & Nicolas Puig, social anthropologists, asked inhabitants of Cairo megapolis in Egypt to record the surrounding urban sounds during one of their daily journeys (without the researcher), equipped with binaural microphones and GPS device. Participants have recorded in different Cairo neighbourhoods, and are themselves from different generations, social and economic backgrounds, and different genders.</p> <p>We obtained accounts of the soundwalks in which participants describe and comment on the sounds heard while relistening to their recorded walk. This material comprises many pages of transcriptions in Arabic from which we have extracted elements related to the verbalization of their sound experience. We identified 600 entries divided into five classes: “nouns,” “sound sources,” “qualificatives/descriptives,” “actions/ verbs,” and “localizations of the sound event.” Together they form the lexicon of what can be called the “natural language of sounds” in Cairo. See https://vbat.org/article831</p>
Integron array MICs and cassettes transcription data
<p>Mobile integrons are widespread genetic platforms that allow bacteria to modulate the expression of antibiotic resistance cassettes by shuffling their position from a common promoter. Antibiotic stress induces the expression of an integrase that excises and integrates cassettes, and this unique recombination and expression system is thought to allow bacteria to 'evolve on demand' in response to antibiotic pressure. To test this hypothesis, we inserted a custom three cassette integron into <em>P. aeruginosa</em>, and used experimental evolution to measure the impact of integrase activity on adaptation to gentamicin. Crucially, integrase activity accelerated evolution by increasing the expression of a gentamicin resistance cassette through duplications and by eliminating redundant cassettes. Importantly, we found no evidence of deleterious off-target effects of integrase activity. Our results show that integrons accelerate resistance evolution by rapidly generating combinatorial variation in cassette composition while maintaining genomic integrity, and they highlight the importance of semi-conservative cassette excision for integron dynamics.</p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.