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7
datasets available to search
ShareScore release 0.9.0
Dataset results
7 results for “MSN”
MSN (Moesin); A Target Enabling Package
<p>Moesin (MSN; membrane-organizing extension spike protein) contains a FERM domain (Four-point-1, Ezrin, Radixin, Moesin) that links transmembrane receptors such as CD44 to the actin cytoskeleton, in a manner regulated by phosphorylation and PIP2. A proteomic, post-mortem analysis of >400 brains identified a protein co-expression module that is highly correlated with pathological and cognitive measures of Alzheimer’s disease (AD). Moesin and CD44 have emerged as key drivers in the module. MSN is highly expressed in microglia and brain endothelium (as well as several non-brain tissues). This TEP targets the CD44-MSN interaction, to test the hypothesis that inhibiting the CD44-MSN interaction would reverse harmful activities of microglia and provide beneficial outcomes for AD patients.</p>
Targeted Metabolite Analysis of alkaloids in Different tissues and Processed seeds of Strychnos nux-vomica using LC-Q-TOF-MSn
Open the record for dataset details and reuse information.
Investigating the Impact of Genetic MSN Depletion on Gene Expression in MDA-MB-231 Breast Cancer Cells
GEO Series GSE272103. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcription factor Sp9 is a negative regulator of D1-type MSN development [scRNA-Seq]
GEO Series GSE202523. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
The Transcription Factor Zfp503 Promotes the D1 MSN Identity and Represses the D2 MSN Identity
GEO Series GSE202439. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Transcription factor Sp9 is a negative regulator of D1-type MSN development
GEO Series GSE202551. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Transcription factor Sp9 is a negative regulator of D1-type MSN development [RNA-Seq]
GEO Series GSE202550. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.