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2 results for “Macaca mulatta; Primates”
Neuronal data sample from PMd of non-human primates (Macaca Mulatta) performing a countermanding reaching task
<p>Brief presentation of the subjects and task performed</p> <p>Two adult male rhesus macaque monkeys (Macaca mulatta; P, C) performed a countermanding reaching task. All experimental procedures, animal care, housing, and surgical procedures conformed with European (Directive 86/609/ECC and 2010/63/UE) and Italian (D.L. 116/92 and D.L. 26/2014) laws on the use of nonhuman primates in scientific research and were approved by the Italian Ministry of Health. In both monkeys a 96 channels Utah arrays (BlackRock Microsystem, USA) was employed to record neuronal activity from the dorsal premotor cortex (PMd) contralateral to the arm employed during the task.</p> <p>Behavioral task</p> <p>Monkeys performed a countermanding reaching task interacting with visual stimuli presented on a touch-screen. Each trial started with the presentation of a central stimulus (red dot) that they had touch with their finger and hold (400-900ms). Thereafter the central stimulus disappeared and, simultaneously, a target appeared (go signal) randomly at one of two opposite positions (left or right). In no-stop trials to perform a correct trial, monkeys had to move their hand form the central target, touch peripheral target and to maintain their fingers on it for a random time (400-800 ms). In stop trials at a variable delay (Stop signal delay, SSD) after the go signal was presented, the central stimulus reappeared (Stop signal) instructing the monkey to keep the hand on the starting position (additional holding time; 400-1000 ms) to perform a correct-stop trial. If the monkey moved the hand during stop trials, the trial was considered a wrong-stop trial. No-stop and stop trials were randomly intermingled in such a way that the no-stop trials were more frequent.</p> <p>Recordings</p> <p>The neuronal activity from each electrode was recorded by employing a Tucker Davies Technologies RZ2 system (sampling rate at 24.4 Khz). Single unit activity was then isolated by using Kilosort (Pachitariu, et al. in Advances in Neural information processing systems (2016) 4448-4456).</p> <p>Data and code reproduce and are linked the main figures and results of the paper "Neuronal population dynamics during motor plan cancellation in non-human primates" , <em>Proceedings of the National Academy of Sciences</em> (<em>PNAS</em>)</p> <p>For further inquiry please contact: stefano.ferraina@uniroma1.it or pierpaolo.pani@uniroma1.it</p> <p> </p>
Seasonal transcriptome atlas of 80 neural and peripheral tissues of male and female non-human primate Macaca mulatta
GEO Series GSE201986. Macaca mulatta. 924 samples. Type: Expression profiling by high throughput sequencing.
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