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17
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ShareScore release 0.9.0
Dataset results
17 results for “Macrophage migration inhibitory factor”
Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors
ClinicalTrials.gov study NCT01765790. IPD Sharing: YES. Countries: 2. Publications: 1.
Pilot Study: The Role of Macrophage Migration Inhibitory Factor (MIF) in Spinal Cord Injury
ClinicalTrials.gov study NCT00919581. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Role of Macrophage Migration Inhibitory Factor (MIF) in Heart Failure
ClinicalTrials.gov study NCT03232671. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Macrophage migration inhibitory factor is involved in ectopic endometrial tissue growth and peritoneal-endometrial tissue interaction in vivo: a plausible link to endometriosis development
Pelvic inflammation is a hallmark of endometriosis pathogenesis and a major cause of the disease's symptoms. Abnormal immune and inflammatory changes may not only contribute to endometriosis-major symptoms, but also contribute to ectopic endometrial tissue growth and endometriosis development. A major pro-inflammatory factors found elevated in peritoneal fluid of women with endometriosis and to be overexpressed in peritoneal fluid macrophages and active, highly vascularized and early stage endometriotic lesions, macrophage migration inhibitory factor (MIF) appeared to induce angiogenic and inflammatory and estrogen producing phenotypes in endometriotic cells in vitro and to be a possible therapeutic target in vivo. Using a mouse model where MIF-knock out (KO) mice received intra-peritoneal injection of endometrial tissue from MIF-KO or syngeneic wild type (WT) mice and vice versa, our current study revealed that MIF genetic depletion resulted in a marked reduction ectopic endometrial tissue growth, a disrupted tissue structure and a significant down regulation of the expression of major inflammatory (cyclooxygenease-2), cell adhesion (αv and β3 integrins), survival (B-cell lymphoma-2) and angiogenic (vascular endothelial cell growth) factorsrelevant to endometriosis pathogenesis, whereas MIF add-back to MIF-KO mice significantly restored endometriosis-like lesions number and size. Interestingly, cross-experiments revealed that MIF presence in both endometrial and peritoneal host tissues is required for ectopic endometrial tissue growth and pointed to its involvement in endometrial-peritoneal interactions. This study provides compelling evidence for the role of MIF in endometriosis development and its possible interest for a targeted treatment of endometriosis.
The Relation Between Macrophage Migration Inhibitory Factor (MIF) and 25(OH) Vitamin D3 Serum Levels in Rheumatoid Arthritis
ClinicalTrials.gov study NCT04315818. IPD Sharing: YES. Countries: 0. Publications: 5.
Data from: Macrophage migration inhibitory factor is involved in ectopic endometrial tissue growth and peritoneal-endometrial tissue interaction in vivo: a plausible link to endometriosis development
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Macrophage migration inhibitory factor is overproduced through EGR1 in TET2low resting monocytes
GEO Series GSE188624. Homo sapiens. 52 samples. Type: Expression profiling by high throughput sequencing.
Macrophage-Mediated Bone Formation of Scaffolds Modified with MSC-derived Extracellular Matrix Depends on Migration Inhibitory Factor Signaling Pathway
GEO Series GSE174477. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Changes of Macrophage Migration Inhibitory Factor During Orthotopic Liver Transplantation
ClinicalTrials.gov study NCT02695979. IPD Sharing: NO. Countries: 1. Publications: 0.
Macrophage Migration Inhibitory Factor (MIF)- Cardiac Surgery
ClinicalTrials.gov study NCT01267721. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Lupus Nephritis
ClinicalTrials.gov study NCT01541670. IPD Sharing: Not stated. Countries: 5. Publications: 0.
Improving Immunotherapy Responses by Dual Inhibition of Macrophage Migration Inhibitory Factor and PD-1
GEO Series GSE306115. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing; Other.
Macrophage migration inhibitory factor in inflammasome formation and macrophage recruitment in cervical cell carcinoma
GEO Series GSE280733. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
The effect of soluble CD74 (sCD74) and recombinant macrophage migration inhibitory factor (MIF) treatment on the gene expression profile in cardiac myofibroblasts
GEO Series GSE108999. Mus musculus. 12 samples. Type: Expression profiling by array.
Macrophage migration inhibitory factor (MIF) is essential for Type 2 effector cell immunity to an intestinal helminth parasite
GEO Series GSE139009. Mus musculus. 47 samples. Type: Expression profiling by array.
Macrophage Migration Inhibitory Factor for Diagnosing Endometriosis and Its Severity
ClinicalTrials.gov study NCT04091997. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Inhibition of macrophage migration inhibitory factor (MIF) suppresses apoptosis signal-regulating kinase 1 to protect against liver ischemia/reperfusion injury
GEO Series GSE212508. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.