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ShareScore release 0.9.0
Dataset results
60 results for “Malignant biliary obstruction”
Treatment of Distal Malignant Biliary Obstruction by Uncovered, Partially Covered, or Fully Covered Metal Stents
ClinicalTrials.gov study NCT06453590. IPD Sharing: YES. Countries: 1. Publications: 34.
Plastic vs. Covered Metal vs. Uncovered Metal Biliary Stents for the Management of Malignant Biliary Obstruction
ClinicalTrials.gov study NCT01038713. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Percutaneous transhepatic or endoscopic ultrasound-guided biliary drainage in malignant distal bile duct obstruction using a metal stent: study protocol for a prospective European multicentre trial (PUMa trial)
<p><strong>Abstract:</strong></p> <p><strong>Background</strong></p> <p>Percutaneous transhepatic biliary drainage [PTBD] is still universally used in patients with malignant distal bile duct obstruction when endoscopic retrograde cholangiopancreatography [ERCP] is not successful or not possible to perform. However, endoscopic ultrasound-guided biliary drainage [EUS-BD] was associated with better clinical success and a lower rate of adverse events (AE) in recent comparative studies, although further improvements in the PTBD technique, such as primary stent implantation as a one-step procedure, percutaneous ultrasound-guided bile duct puncture and left-sided bile duct access, were not considered. The aim of this study is to compare both procedures carried out as intended one-step procedures with primary metal stent insertion.</p> <p><strong>Methods</strong></p> <p>The PUMa trial is an ongoing European non-randomized, controlled, parallel group, non-inferiority multicentre trial. Fourteen study centres perform only one of the two procedures with regard to the best local experience. PTBD is performed as a one-step procedure with primary metal stent insertion after percutaneous ultrasound-guided bile duct access. EUS-BD is performed as a one-step procedure using the EUS-guided trans-gastric or trans-duodenal access route for trans-gastric trans-hepatic (EUS-HGS), trans-duodenal (EUS-CDS) or antegrade trans-papillary (EUS-AGS) metal stent insertion. The main target values are the technical and clinical success rates, AEs within 30 days and overall disease-specific survival within 6 months. The calculated total number of cases is 212 patients.</p> <p><strong>Discussion:</strong></p> <p>The PUMa trial investigates whether PTBD is not inferior to EUS-BD in terms of technical and clinical success if primary metal stent insertion is performed as a one-step procedure in both procedures. Differences are expected in the quantity and variety of AEs, number of re-interventions and length of hospital stay.</p> <p><strong>Trial Registration</strong>: ClinicalTrials.gov ID: NCT03546049 (date of registration 22.05.2018)</p>
IRS(Irradiation Stent) vs. CS(Conventional Stent) Insertion in Inoperable Malignant Biliary Obstruction
ClinicalTrials.gov study NCT02001779. IPD Sharing: NO. Countries: 1. Publications: 1.
Prospective Study Comparing EUS vs ERCP Stent Insertion for Malignant Biliary Obstruction
ClinicalTrials.gov study NCT01421836. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Unilateral Stenting Versus Bilateral Stenting for Malignant Hilar Biliary Obstruction
ClinicalTrials.gov study NCT02649712. IPD Sharing: NO. Countries: 1. Publications: 10.
Sems Placement With and Without Biliary Sphincterectomy in Patients With Malignant Biliary Obstruction
ClinicalTrials.gov study NCT04805450. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Efficacy of Partial Covered Double Bare Metal Stent Compared to Uncovered Double Bare Metal Stent in Malignant Biliary Obstruction
ClinicalTrials.gov study NCT02937246. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study for Efficacy of Side-by-side Compared to Stent-in-stent Technique in the Endoscopic Management of Malignant Hilar Biliary Obstruction
ClinicalTrials.gov study NCT02659852. IPD Sharing: NO. Countries: 1. Publications: 2.
Endoscopic Biliary RFA of Malignant Bile Duct Obstruction
ClinicalTrials.gov study NCT02582541. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Prospective Randomized Study for Efficacy of Uncovered Double Bare Metallic Stent Compared to Uncovered Single Bare Metallic Stent in Malignant Biliary Obstruction
ClinicalTrials.gov study NCT01869894. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Single Versus Multiple Deployment of Metallic Stents for Inoperable Malignant Hilar Biliary Obstruction
ClinicalTrials.gov study NCT02166970. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
EUS-guided Biliary Drainage vs. ERCP Assisted Transpapillary Drainage for Malignant Biliary Obstruction
ClinicalTrials.gov study NCT03812250. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Winged Perimeter Versus Traditional Plastic Biliary Stent for Malignant Bile Duct Obstruction
ClinicalTrials.gov study NCT01514214. IPD Sharing: NO. Countries: 1. Publications: 1.
Comparison of a Plastic Stent Without Central Lumen With Self Expandable Metal Stents in Patients With Malignant Distal Biliary Obstruction
ClinicalTrials.gov study NCT01063634. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Radiofrequency Ablation for Malignant Biliary Obstruction
ClinicalTrials.gov study NCT01758341. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Comparison of Drug Eluting Stent and Covered Metal Stent in Malignant Biliary Obstruction (MIRA III)
ClinicalTrials.gov study NCT02460432. IPD Sharing: YES. Countries: 1. Publications: 1.
EUS-Guided Biliary Drainage in Patients With Inoperable Malignant Distal Biliary Obstruction and Failed ERCP: a Prospective Feasibility Multicenter Trial
ClinicalTrials.gov study NCT01889953. IPD Sharing: Not stated. Countries: 5. Publications: 1.
Eus-giuded Biliary Drainage With Ec-lams vs ERCP as a Primary Intervention for Endoscopic Treatment of Patinets With Distal Malignant Biliary Obstruction
ClinicalTrials.gov study NCT04099862. IPD Sharing: NO. Countries: 1. Publications: 1.
RADIO FREQUENCY ABLATION IN UNRESECTABLE MALIGNANT BILIARY OBSTRUCTION
ClinicalTrials.gov study NCT05320328. IPD Sharing: NO. Countries: 1. Publications: 1.
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