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Example Microscopy Metadata JSON files produced using Micro-Meta App to document example microscopy experiments performed at individual core facilities
<p>Example <strong>Microscopy Metadata </strong>(Microscope.JSON and Settings.JSON)<strong> files </strong>produced using<strong> <a href="https://wu-bimac.github.io/MicroMetaApp.github.io/">Micro-Meta App</a> </strong>to document the <strong>Hardware Specifications</strong> of example Microscopes and the <strong>Image Acquisition Settings</strong> utilized to acquire example images as listed in the table below.</p> <blockquote> <p>For each facility, the dataset contains two JSON files:</p> <ol> <li><strong>Microscope.JSON file</strong> (e.g., 01_marcello_uliverpool_cci_zeiss_axioobserz1_lsm710.json)</li> <li><strong>Settings.JSON file</strong> (indicated with the name of the image and with the _AS suffix)</li> </ol> </blockquote> <p><strong>Micro-Meta App was</strong> developed as part of a <strong>global community initiative</strong> including the <a href="http://www.4dnucleome.org/"><strong>4D Nucleome (4DN)</strong> </a>Imaging Working Group, <strong>BioImaging North America (BINA)</strong> <a href="https://www.bioimagingna.org/qc-dm-wg">Quality Control and Data Management Working Group</a>, and <strong>QUAlity and REProducibility for Instrument and Images in Light Microscopy</strong> (<a href="https://quarep.org/"><strong>QUAREP-LiMi</strong></a>), to extend the <strong>Open Microscopy Environment (OME)</strong> <a href="https://www.openmicroscopy.org/Schemas/Documentation/Generated/OME-2016-06/ome.html">data model</a>.</p> <blockquote> <p>The works of this <strong>global community effort</strong> resulted in multiple publications featured on a recent <strong>Nature Methods FOCUS ISSUE </strong>dedicated to <a href="https://www.nature.com/collections/djiciihhjh">Reporting and reproducibility in microscopy</a>.</p> </blockquote> <blockquote> <p><strong>Learn More!</strong> For a thorough description of <strong>Micro-Meta App</strong> consult our recent <a href="https://doi.org/10.1038/s41592-021-01315-z">Nature Methods</a> and <a href="https://doi.org/10.1101/2021.05.31.446382">BioRxiv.org</a> publications!</p> </blockquote> <p> </p> <table> <tbody> <tr> <td><strong>Nr.</strong></td> <td><strong>Manufacturer</strong></td> <td><strong>Model</strong></td> <td><strong>Tier</strong></td> <td><strong>Εxperiment Type</strong></td> <td><strong>Facility Name</strong></td> <td><strong>Department and Institution</strong></td> <td><strong>URL</strong></td> <td><strong>References</strong></td> </tr> <tr> <td>1</td> <td><strong>Carl Zeiss Microscopy</strong></td> <td><strong>Axio Observer Z1 (with LSM 710 scan head)</strong></td> <td>1</td> <td>3D visualization of superhydrophobic polymer-nanoparticles</td> <td>Centre for Cell Imaging (CCI)</td> <td>University of Liverpool</td> <td>https://cci.liv.ac.uk/equipment_710.html</td> <td>Upton et al., 2020</td> </tr> <tr> <td>2</td> <td><strong>Carl Zeiss Microscopy</strong></td> <td><strong>Axio Observer (Axiovert 200M)</strong></td> <td>2</td> <td>Μeasurement of illumination stability on Chinese Hamster Ovary cells expressing Paxillin-EGFP</td> <td>Advanced BioImaging Facility (ABIF).</td> <td>McGill University</td> <td>https://www.mcgill.ca/abif/equipment/axiovert-1</td> <td>Kiepas et al., 2020</td> </tr> <tr> <td>3</td> <td><strong>Carl Zeiss Microscopy</strong></td> <td><strong>Axio Observer Z1 (with Spinning Disk)</strong></td> <td>2</td> <td>Immunofluorescence imaging of cryosection of Mouse kidney</td> <td>Imagerie Cellulaire; Quality Control managed by Miacellavie (https://miacellavie.com/)</td> <td>Centre de recherche du Centre Hospitalier Université de Montréal (CR CHUM), University of Montreal</td> <td>https://www.chumontreal.qc.ca/crchum/plateformes-et-services (the web site is for all core facilities, not specifically for the core facility hosting this microscope)</td> <td>Pilliod et al., 2020</td> </tr> <tr> <td>4</td> <td><strong>Carl Zeiss Microscopy</strong></td> <td><strong>Axio Imager Z2 (with Apotome)</strong></td> <td>2</td> <td>Immunofluorescence imaging of mitotic division in Hela cells using </td> <td>Bioimaging Unit</td> <td>Newcastle University</td> <td>https://www.ncl.ac.uk/bioimaging/</td> <td>Watson et al., 2020</td> </tr> <tr> <td>5</td> <td><strong>Carl Zeiss Microscopy</strong></td> <td><strong>Axio Observer Z1</strong></td> <td>2</td> <td>Fluorescence microscopy of human skin fibroblasts from Glycogen Storage Disease patients.</td> <td>Life Imaging Center (LIC)</td> <td>Centre for Integrative Signalling Analysis (CISA), University of Freiburg</td> <td>https://miap.eu/equipments/sd-i-abl/</td> <td>Hannibal et al., 2020</td> </tr> <tr> <td>6</td> <td><strong>Leica Microsystems</strong></td> <td><strong>DMI6000B</strong></td> <td>2</td> <td>3D immunofluorescence imaging rhinovirus infected macrophages </td> <td>IMAG'IC Confocal Microscopy Facility</td> <td>Institut Cochin, CNRS, INSERM, Université de Paris</td> <td>https://www.institutcochin.fr/core_facilities/confocal-microscopy/cochin-imaging-photonic-microscopy/organigram_team/10054/view</td> <td>Jubrail et al., 2020</td> </tr> <tr> <td>7</td> <td><strong>Leica Microsystems</strong></td> <td><strong>DM5500B</strong></td> <td>2</td> <td>Immunofluorescence analysis of the colocalization of PML bodies with DNA double-strand breaks</td> <td>Bioimaging Unit</td> <td>Edwardson Building on the Campus for Ageing and Vitality, Newcastle University</td> <td>https://www.ncl.ac.uk/bioimaging/equipment/leica-dm5500/#overview</td> <td>da Silva et al., 2019; Nelson et al., 2012<br> </td> </tr> <tr> <td>8</td> <td><strong>Leica Microsystems</strong></td> <td><strong>DMI8-CS (with TCS SP8 STED 3X)</strong></td> <td>2</td> <td>Live-cell imaging of N. benthamiana leaves cells-derived protoplasts</td> <td>Center for Advanced Imaging (CAi)</td> <td>School of Mathematics/Natural Sciences, Heinrich-Heine-Universität Düsseldorf</td> <td>https://www.cai.hhu.de/en/equipment/super-resolution-microscopy/leica-tcs-sp8-sted-3x</td> <td>Singer et al., 2017; Hänsch et al., 2020</td> </tr> <tr> <td>9</td> <td><strong>Nikon Instruments</strong></td> <td><strong>Eclipse Ti</strong></td> <td>2</td> <td>Immunofluorescence analysis of the cytoskeleton structure in COS cells</td> <td>Advanced Imaging Center (AIC)</td> <td>Janelia Research Campus, Howard Hughes Medical Institute</td> <td>https://www.janelia.org/support-team/light-microscopy/equipment</td> <td>Abdelfattah et al., 2019; Qian et al., 2019; Grimm et al., 2020</td> </tr> <tr> <td>10</td> <td><strong>Nikon Instruments</strong></td> <td><strong>Eclipse Ti-E (HCA)</strong></td> <td>2</td> <td>Τime-lapse analysis of the bursting behavior of amine-functionalized vesicular assemblies</td> <td>Light Microscopy Facility (IALS-LIF)</td> <td>Institute for Applied Life Sciences, University of Massachusetts at Amherst</td> <td>https://www.umass.edu/ials/light-microscopy</td> <td>Fernandez et al., 2020</td> </tr> <tr> <td>11</td> <td><strong>Nikon Instruments/Coleman laboratory (customized)</strong></td> <td><strong>TIRF HILO Epifluorescence light Microscope (THEM)/ Eclipse Ti</strong></td> <td>2</td> <td>Single-particle tracking of Halo-tagged PCNA in Lox cells</td> <td>Coleman laboratory</td> <td>Anatomy and Structural Biology Department, The Albert Einstein College of Medicine</td> <td>https://einsteinmed.org/faculty/12252/robert-coleman/</td> <td>Drosopoulos et al., 2020</td> </tr> <tr> <td>12</td> <td><strong>Nikon Instruments</strong></td> <td><strong>Eclipse Ti (with Andor Dragon Fly Spinning Disk)</strong></td> <td>2</td> <td>Investigation of the 3D structure of cerebral organoids</td> <td>Montpellier Resources Imagerie</td> <td>Centre de Recherche de Biologie cellulaire de Montpellier (MRI-CRBM), CNRS, Univerity of Montpellier</td> <td>https://www.mri.cnrs.fr/en/optical-imaging/our-facilities/mri-crbm.html</td> <td>Ayala-Nunez et al., 2019</td> </tr> <tr> <td>13</td> <td><strong>Nikon Instruments</strong></td> <td><strong>Eclipse Ti2</strong></td> <td>2</td> <td>Ιmmunofluorescence imaging of cryosections of mouse hearth myocardium </td> <td>Neuroscience Center Microscopy Core</td> <td>Neuroscience Center, University of North Carolina</td> <td>https://www.med.unc.edu/neuroscience/core-facilities/neuro-microscopy/</td> <td>Aghajanian et al., 2021</td> </tr> <tr> <td>14</td> <td><strong>Nikon Instruments</strong></td> <td><strong>Eclipse Ti2</strong></td> <td>2</td> <td>Live-cell imaging of bacterial cells expressing GFP-PopZ</td> <td>Microscopy Resources on the North Quad (MicRoN)</td> <td>Harvard Medical School </td> <td>https://micron.hms.harvard.edu/</td> <td>Lim and Bernhardt 2019; Lim et al., 2019</td> </tr> <tr> <td>15</td> <td><strong>Olympus/Biomedical Imaging Group (customized)</strong></td> <td><strong>TIRF Epifluorescence Structured light Microscope (TESM)/IX71</strong></td> <td>3</td> <td>3D distribution of HIV-1 in the nucleus of human cells</td> <td>Biomedical Imaging Group</td> <td>Program in Molecular Medicine, University of Massachusetts Medical School</td> <td>https://trello.com/b/BQ8zCcQC/tirf-epi-fluorescence-structured-light-microscope</td> <td>Navaroli et al., 2012</td> </tr> <tr> <td>16</td> <td><strong>Olympus/Computer Vision Laboratory (customized)</strong></td> <td><strong>3D BrightField Scanner/IX71</strong></td> <td>3</td> <td>Transmitted light brightfield visualization of swimming spermatocytes</td> <td>Laboratorio Nacional de Microscopia Avanzada (LNMA) and Computer Vision Laboratory of the Institute of Biotechnology</td> <td>Universidad Nacional Autonoma de Mexico (UNAM)</td> <td>https://lnma.unam.mx/wp/</td> <td>Pimentel et al., 2012; Silva-Villalobos et al., 2014</td> </tr> </tbody> </table> <p><strong>Getting started</strong></p> <p>Use these videos to get started with using Micro-Meta App after installation into OMERO and downloading the example data files:</p> <ol> <li><a href="https://vimeo.com/562022222">Video 1</a></li> <li><a href="https://vimeo.com/562022281">Video 2</a></li> </ol> <p><strong>More information</strong></p> <blockquote> <p>For full information on how to use Micro-Meta App please utilize the following resources:</p> <ol> <li>Micro-Meta App <a href="https://wu-bimac.github.io/MicroMetaApp.github.io/">website</a></li> <li><a href="https://micrometaapp-docs.readthedocs.io/en/latest/index.html">Full documentation</a></li> <li><a href="https://micrometaapp-docs.readthedocs.io/en/latest/docs/intro/installation.html">Installation</a> instructions</li> <li><a href="https://micrometaapp-docs.readthedocs.io/en/latest/docs/tutorials/index.html#step-by-step-instructions">Step-by-Step Instructions</a></li> <li><a href="https://micrometaapp-docs.readthedocs.io/en/latest/docs/tutorials/VideoTutorials.html#micro-meta-app-video-tutorials">Tutorial Videos</a></li> </ol> </blockquote> <p><strong>Background</strong></p> <p>If you want to learn more about the importance of <strong>metadata and quality contro</strong>l to ensure full <strong>reproducibility, quality and scientific value</strong> in light microscopy, please take a look at our recent publications describing the development of community-driven light <strong>4DN-BINA-OME Microscopy Metadata</strong> specifications <a href="https://doi.org/10.1038/s41592-021-01327-9">Nature Methods</a> and <a href="https://doi.org/10.1101/2021.04.25.441198">BioRxiv.org</a> and our <a href="https://arxiv.org/abs/1910.11370">overview manuscript</a> entitled <strong>A perspective on Microscopy Metadata: data provenance and quality control</strong>.</p> <p> </p> <p> </p>
Example Microscopy Metadata JSON files produced using Micro-Meta App to document the acquisition of example images using a custom-built TIRF Epifluorescence Structured Illumination Microscope
<p><strong>Example Microscopy Metadata JSON files produced using the <a href="https://wu-bimac.github.io/MicroMetaApp.github.io/">Micro-Meta App</a> documenting an example raw-image file acquired using the custom-built TIRF Epifluorescence Structured Illumination Microscope.</strong></p> <p>For this use case, which is presented in Figure 5 of <a href="http://doi: https://doi.org/10.1101/2021.05.31.446382">Rigano et al., 2021</a>, Micro-Meta App was utilized to document:</p> <p>1) The <strong>Hardware Specifications</strong> of the custom build TIRF Epifluorescence Structured light Microscope (TESM; <a href="https://www.pnas.org/content/109/8/E471.long">Navaroli et al., 2010</a>) developed, built on the basis of the based on Olympus IX71 microscope stand, and owned by the Biomedical Imaging Group (http://big.umassmed.edu/) at the Program in Molecular Medicine of the University of Massachusetts Medical School. Because TESM was custom-built the most appropriate documentation level is <strong>Tier 3</strong> (<em>Manufacturing/Technical Development/Full Documentation</em>) as specified by the <a href="https://doi.org/10.5281/zenodo.4710731">4DN-BINA-OME</a> Microscopy Metadata model (<a href="https://doi.org/10.1101/2021.04.25.441198">Hammer et al., 2021</a>).</p> <p>The TESM Hardware Specifications are stored in: <strong>Rigano et al._Figure 5_UseCase_Biomedical Imaging Group_TESM.JSON</strong></p> <p>2) The <strong>Image Acquisition Settings</strong> that were applied to the TESM microscope for the acquisition of an example image (FSWT-6hVirus-10minFIX-stk_4-EPI.tif.ome.tif) obtained by Nicholas Vecchietti and Caterina Strambio-De-Castillia. For this image, TZM-bl human cells were infected with HIV-1 retroviral three-part vector (FSWT+PAX2+pMD2.G). Six hours post-infection cells were fixed for 10 min with 1% formaldehyde in PBS, and permeabilized. Cells were stained with mouse anti-p24 primary antibody followed by DyLight488-anti-Mouse secondary antibody, to detect HIV-1 viral Capsid. In addition, cells were counterstained using rabbit anti-Lamin B1 primary antibody followed by DyLight649-anti-Rabbit secondary antibody, to visualize the nuclear envelope and with DAPI to visualize the nuclear chromosomal DNA.</p> <p>The Image Acquisition Settings used to acquire the FSWT-6hVirus-10minFIX-stk_4-EPI.tif.ome.tif image are stored in: <strong>Rigano et al._Figure 5_UseCase_AS_fswt-6hvirus-10minfix-stk_4-epi.tif.JSON</strong></p> <p><em><strong>Instructional video tutorials on how to use these example data files:</strong></em><br> Use these videos to get started with using Micro-Meta App after downloading the example data files available here.</p> <ul> <li><a href="https://vimeo.com/562022222">Part 1/2</a></li> <li><a href="https://vimeo.com/562022281">Part 2/2</a></li> </ul>
Meta-analysis and gender classification of 914 national and international surveys in six European countries (2000-2023)
<p><span>This data frame presents the results of a quan</span><span>ti</span><span>ta</span><span>ti</span><span>ve content analysis of the occurrence of gender‐based concepts, themes, issues, and solu</span><span>ti</span><span>ons within large‐scale poli</span><span>ti</span><span>cal and sociological survey ques</span><span>ti</span><span>onnaires fielded cross‐na</span><span>ti</span><span>onally in Europe and in six European countries: Denmark, Germany, Hungary, Switzerland and the UK, spanning 2000‐2023. Data was collected by teams from each country between September 2023‐January 2024. Teams collected ques</span><span>ti</span><span>ons in the original language and provided a transla</span><span>ti</span><span>on into English. Analysis was conducted using the translated text. The unit of analysis (‘CODING_UNIT_TEXT’) was the individual 'gender‐related argument' within a survey ques</span><span>ti</span><span>on. This could be the en</span><span>ti</span><span>re survey ques</span><span>ti</span><span>on, a sub‐ques</span><span>ti</span><span>on (in the case of matrix ques</span><span>ti</span><span>ons), or a singular response op</span><span>ti</span><span>on (for mul</span><span>ti</span><span>ple choice ques</span><span>ti</span><span>ons). Coding units were coded in three key domains:(1) Gender concepts, (2) Themes/issues, and (3) Solu</span><span>ti</span><span>ons. Up to two Themes/Issues and Solu</span><span>ti</span><span>ons could be coded per coding unit. Several coding categories within the Themes/Issues and Solu</span><span>ti</span><span>ons domains func</span><span>ti</span><span>on hierarchically, where a coder first assigned a higher‐level category and then as many subcategories as applicable. For example, a ques</span><span>ti</span><span>on concerning government‐funded childcare is coded as B1_Economy ‐> B1_4_LabourMarket ‐> B1_4_1_CareWork ‐> B1_4_1_3_Childcare. The corresponding codebook presents the uni</span><span>ti</span><span>sa</span><span>ti</span><span>on process and coding categories in full detail.</span></p>
Meta-analysis reveals controls on oyster predation 1977-2021
This dataset was created for investigating the patterns and drivers of variation in predation strength on oysters. Predation on oysters has been the subject of intense study because oysters are vital to creating coastal habitat, sustaining biodiversity, and enhancing or stabilizing important ecosystem functions. Understanding how predators affect oyster populations is important given the global decline in oysters and the substantial efforts focused on re-establishment and conservation. Despite widespread losses of oyster reefs, there have been no standardized and integrated quantitative assessments of the influence of predators on oysters. Therefore, this dataset was created by combining the results of 49 peer-reviewed articles reporting 384 experiments on oyster predation. These field and laboratory experiments tested whether the presence of predators affects oyster mortality or recruitment. The combined data was used in a meta-analysis, the results of which are published in the paper titled Meta-analysis reveals controls on oyster predation (Tedford and Castorani 2022), which represents the first quantitative synthesis to show that across a range of environments, predators have strong impacts on oysters.
Meta-analysis of ecosystem services associated with oyster restoration on the Eastern and Gulf coasts of the US
We conducted a meta-analysis to systematically quantify the success and uncertainty of oyster reef restoration for a suite of biological, biogeochemical, and physical ecosystem services relative to both degraded and natural reference habitats. We focused on the eastern oyster, Crassostrea virginica. To evaluate whether restored eastern oyster reefs enhance ecosystem services relative to unaltered, degraded habitats and whether restored reefs provide ecosystem services equivalent to reference reefs, we synthesized data and calculated log response ratios for 245 restored-degraded reef pairs and 136 restored-reference reef pairs from 106 publications collected along 3500 km of U.S. Gulf of Mexico and Atlantic coastlines.
LoRaWAN Dense Indoor Sensor Network (DISN) Transmission Meta Data
<p>We present a large data of indoor Long Range Wide Area Network (LoRaWAN) network metadata to study Dense Indoor Sensor Networks (DISN). We collected 14 million transmissions from 390 sensors between date February 2020 and date September 2020. The transmissions have been received by 3 gateways across 8 floors and distances up to 64 m. The prototype will run in the background throughout the project and the data set will be regularly updated.</p> <p> </p>
GWAS Summary Statistics from "Sex and statin-related genetic associations at the PCSK9 gene locus – results of genome-wide association meta-analysis"
<p>GWAMA summary statistics of PCSK9 levels stratified by sex and statin useage in Europeans.</p> <p>When using this data, please cite:</p> <p>Pott, J., Kheirkhah, A., Gadin, J.R. <em>et al.</em> Sex and statin-related genetic associations at the <em>PCSK9</em> gene locus: results of genome-wide association meta-analysis. <em>Biol Sex Differ</em> <strong>15</strong>, 26 (2024). https://doi.org/10.1186/s13293-024-00602-6</p> <p>All txt files contain the following columns:</p> <ul> <li>markername (unique SNP ID)</li> <li>chr</li> <li>bp_hg19 (base position according to hg19)</li> <li>EA (effect allele)</li> <li>OA (other allele)</li> <li>EAF (effect allele frequency)</li> <li>info (minimal info score across all used studies)</li> <li>nSamples (sample size per SNP)</li> <li>nStudies (in case of double-stratified data: number of studies; in case of single-stratified data: 2, as it is a meta-analysis of the two double-stratified data sets)</li> <li>beta (effect estimate)</li> <li>SE (standard error)</li> <li>pval (p-value)</li> <li>I2 (SNP heterogeneity across studies)</li> <li>invalidAssoc (TRUE/FALSE flag if this variant was excluded in our analysis)</li> <li>reason4exclusion (reason why this SNP was excluded)</li> <li>phenotype (phenotyp setting)</li> </ul>
OpenCitations Meta RDF dataset of agent roles metadata and its provenance information
<p>This dataset is a specialized subset of the OpenCitations Meta RDF data, focusing exclusively on data related to <strong>agent roles</strong> of bibliographic resources<strong> </strong>(<a href="http://purl.org/spar/pro/RoleInTime" target="_blank" rel="noopener">http://purl.org/spar/pro/RoleInTime</a>). These agents can be authors, editors, or publishers. It contains all the metadata and its provenance information, structured specifically around agent roles, in JSON-LD format.</p> <p>The inner folders are named through the <strong>supplier prefix</strong> of the contained entities. It is a prefix that allows you to recognize the entity membership index (e.g., OpenCitations Meta corresponds to <strong>06*0</strong>).</p> <p>After that, the folders have <strong>numeric names</strong>, which refer to the range of contained entities. For example, the 10000 folder contains entities from 1 to 10000. Inside, you can find the <strong>zipped </strong>RDF data.</p> <p>At the same level, additional folders containing the <strong>provenance </strong>are named with the same criteria already seen. Then, the 1000 folder includes the provenance of the entities from 1 to 1000. The provenance is located inside a folder called <strong>prov</strong>, also in zipped JSON-LD format.</p> <p>For example, data related to the entity is located in the folder /ar/06250/10000/1000/1000.zip, while information about provenance in /ar/06250/10000/1000/prov/se.zip</p> <p>Additional information about OpenCitations Meta at the <a href="https://opencitations.net/meta" target="_blank" rel="noopener">official webpage</a>.</p>
OpenCitations Meta RDF dataset of page numbers metadata and its provenance information
<p>This dataset is a specialized subset of the OpenCitations Meta RDF data, focusing exclusively on data related to <strong>page numbers</strong> of bibliographic resources, known as <strong>manifestations </strong>(<a href="http://purl.org/spar/fabio/Manifestation" target="_new">http://purl.org/spar/fabio/Manifestation</a>). It contains all the bibliographic metadata and its provenance information, structured specifically around manifestations (page numbers), in JSON-LD format.</p> <p>The inner folders are named through the <strong>supplier prefix</strong> of the contained entities. It is a prefix that allows you to recognize the entity membership index (e.g., OpenCitations Meta corresponds to <strong>06*0</strong>).</p> <p>After that, the folders have <strong>numeric names</strong>, which refer to the range of contained entities. For example, the 10000 folder contains entities from 1 to 10000. Inside, you can find the <strong>zipped </strong>RDF data.</p> <p>At the same level, additional folders containing the <strong>provenance </strong>are named with the same criteria already seen. Then, the 1000 folder includes the provenance of the entities from 1 to 1000. The provenance is located inside a folder called <strong>prov</strong>, also in zipped JSON-LD format.</p> <p>For example, data related to the entity is located in the folder /br/06250/10000/1000/1000.zip, while information about provenance in /br/06250/10000/1000/prov/se.zip</p> <p>Additional information about OpenCitations Meta at the <a href="https://opencitations.net/meta" target="_blank" rel="noopener">official webpage</a>.</p>
OpenCitations Meta RDF dataset of identifiers metadata and its provenance information
<p>This dataset is a specialized subset of the OpenCitations Meta RDF data, focusing exclusively on data related to <strong>identifiers </strong>(<a href="http://purl.org/spar/datacite/Identifier" target="_blank" rel="noopener">http://purl.org/spar/datacite/Identifier</a>) of bibliographic resources. It contains all the metadata and its provenance information, structured specifically around identifiers, in JSON-LD format.</p> <p>The inner folders are named through the <strong>supplier prefix</strong> of the contained entities. It is a prefix that allows you to recognize the entity membership index (e.g., OpenCitations Meta corresponds to <strong>06*0</strong>).</p> <p>After that, the folders have <strong>numeric names</strong>, which refer to the range of contained entities. For example, the 10000 folder contains entities from 1 to 10000. Inside, you can find the <strong>zipped </strong>RDF data.</p> <p>At the same level, additional folders containing the <strong>provenance </strong>are named with the same criteria already seen. Then, the 1000 folder includes the provenance of the entities from 1 to 1000. The provenance is located inside a folder called <strong>prov</strong>, also in zipped JSON-LD format.</p> <p>For example, data related to the entity is located in the folder /id/06250/10000/1000/1000.zip, while information about provenance in /id/06250/10000/1000/prov/se.zip</p> <p>Additional information about OpenCitations Meta at the <a href="https://opencitations.net/meta" target="_blank" rel="noopener">official webpage</a>.</p>
OpenCitations Meta RDF dataset of bibliographic resources metadata and its provenance information
<div> <p>This dataset is a specialized subset of the OpenCitations Meta RDF data, focusing exclusively on data related to <strong>bibliographic resources </strong>(<a href="http://purl.org/spar/fabio/Expression" target="_blank" rel="noopener">http:///purl.org/spar/fabio/Expression</a>). It contains all the metadata and its provenance information, structured specifically around bibliographic resources, in JSON-LD format.</p> <p>The inner folders are named through the <strong>supplier prefix</strong> of the contained entities. It is a prefix that allows you to recognize the entity membership index (e.g., OpenCitations Meta corresponds to <strong>06*0</strong>).</p> <p>After that, the folders have <strong>numeric names</strong>, which refer to the range of contained entities. For example, the 10000 folder contains entities from 1 to 10000. Inside, you can find the <strong>zipped </strong>RDF data.</p> <p>At the same level, additional folders containing the <strong>provenance </strong>are named with the same criteria already seen. Then, the 1000 folder includes the provenance of the entities from 1 to 1000. The provenance is located inside a folder called <strong>prov</strong>, also in zipped JSON-LD format.</p> <p>For example, data related to the entity is located in the folder /br/06250/10000/1000/1000.zip, while information about provenance in /br/06250/10000/1000/prov/se.zip</p> <p>Additional information about OpenCitations Meta at the <a href="https://opencitations.net/meta" target="_blank" rel="noopener">official webpage</a>.</p> <p> </p> </div>
2023 EU Transparency Register - Meta-organizations
<p>For my Research Habilitation Dissertation, I extracted all information from the EU transparency Register</p> <p>There were 12,435 registered organizations as of January 2023 (Source: Transparency Register). On this basis, I attempted to distinguish between meta-organizations and non-meta-organizations. One should keep in mind that this database only concerns organizations and individuals that seek to lobby EU institutions. There are much more meta-organizations worldwide, and many are not concerned with lobbying the EU.</p> <p>I downloaded and organized the database. I added a year column and edited the database in order to identify meta-organizations. There are 13 different categories of organizations or individuals that can be registered: 1) “Academic institutions”, 2) “Associations and networks of public authorities”, 3) “Companies & groups”, 4), “Entities, offices or networks established by third countries”, 5) “Law firms”, 6) “Non-governmental organisations, platforms and networks and similar”, 7) “Organisations representing churches and religious communities”, 8) “Other organisations, public or mixed entities”, 9) “Professional consultancies”, 10) “Self-employed individuals”, 11) “Think tanks and research institutions”, 12) “Trade and business associations”, 13) “Trade unions and professional associations”. </p> <p>Sheet 1 shows the different tables I created for my habilitation. </p>
Data for "Temperate Regenerative Agriculture practices increase soil carbon but not crop yield – a meta-analysis"
<p>Supplementary Files for systematic review and meta-analysis: Temperate Regenerative Agriculture practices increase soil carbon but not crop yield – a meta-analysis</p> <p> </p>
Cancer screening attendance rates in transgender and gender-diverse patients: a systematic review and meta-analysis
<p>Supplementary Data to support the findings of a systematic review investigating cancer screening rates in transgender and gender-diverse individuals.</p>
Efficacy and safety of subcutaneous vs. sublingual immunotherapy in allergic rhinitis: a systematic review and meta-analysis
<p>Allergic rhinitis significantly impacts patients' quality of life, and allergen immunotherapy (AIT) offers an alternative to conventional treatments. This study compares the efficacy and safety of subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) for allergic rhinitis. A comprehensive search of PubMed, Embase, and ClinicalTrials.gov identified nine randomized controlled trials involving 780 patients (427 SCIT, 353 SLIT). The primary outcome was symptom score; secondary outcomes included medication score, symptom medication score, and local and systemic reactions. Results showed SCIT significantly reduced symptom scores compared to SLIT (Pooled SMD: -0.52, 95% CI: -0.60, -0.03, I2 =83%, P<0.05). However, SCIT patients experienced more severe systemic reactions (grade 3&4) than SLIT patients (Pooled SMD: 6.27, 95% CI: 1.47, 26.73, I2 =0%, P=0.01). Other outcomes were comparable between both groups. In conclusion, SCIT is slightly more effective than SLIT but is associated with a higher frequency of severe systemic reactions, guiding clinicians to tailor treatments to individual patient needs.</p>
Dataset for: Smoking does not accelerate leukocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts
<p>Summary dataset (.csv file) and R script (.R file) for the manuscript entitled:</p> <p>Smoking does not accelerate leukocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts.</p> <p>The column names are explained at the beginning of the R script.</p> <p> </p>
Is there a non-invasive biomarker for the early detection of ovarian torsion? A systematic review and meta-analysis
<p>We have performed a systematic review and meta-analysis and identified multiple biomarkers that warrant further study as part of a broader diagnostic panel for ovarian torsion. These include SCUBE1, s-DD, IL-6, IMA and TNF-a. </p>
Dynamic meta-analysis: a method of using global evidence for local decision making (supplementary materials)
<p>Dynamic meta-analysis: a method of using global evidence for local decision making (supplementary materials)</p>
An Empirical Comparison of Meta-Modeling Techniques for Robust Design Optimization
<p>This is the data and source code used in the paper below:</p> <p>Sibghat Ullah, Hao Wang, Stefan Menzel, Bernhard Sendhoff and Thomas Bäck, “An Empirical Comparison of Meta-Modeling Techniques for Robust Design Optimization”, in 2019 IEEE Symposium Series on Computational Intelligence (SSCI), Xiamen, China, 6-9 December 2019, doi: 10.1109/SSCI44817.2019.9002805</p> <p>This research investigates the potential of using meta-modeling techniques in the context of robust optimization namely optimization under uncertainty/noise. A systematic empirical comparison is performed for evaluating and comparing different meta-modeling techniques for robust optimization. The experimental setup includes three noise levels, six meta-modeling algorithms, and six benchmark problems from the continuous optimization domain, each for three different dimensionalities. Two robustness definitions: robust regularization and robust composition, are used in the experiments. The meta-modeling techniques are evaluated and compared with respect to the modeling accuracy and the optimal function values. The results clearly show that Kriging, Support Vector Machine and Polynomial regression perform excellently as they achieve high accuracy and the optimal point on the model landscape is close to the true optimum of test functions in most cases.</p>
Minimal dataset for "Systematic review and meta-analysis of late auditory evoked potentials as a candidate biomarker in the assessment of tinnitus"
<p>This text file contains the minimal dataset necessary to reproduce the results and analyses in the paper: Cardon E et al., "Systematic review and meta-analysis of late auditory evoked potentials as a candidate biomarker in the assessment of tinnitus". Plos One;2020.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.