Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
32
datasets available to search
ShareScore release 0.7.1
Dataset results
32 results for “Microcebus”
MRI Brain Template and Atlas of the Mouse Lemur Primate Microcebus murinus
<p>MRI template and 120-region atlas for the mouse lemur primate Microcebus murinus.<br> <br> Generated from 34 animals aged 15-58 months old scanned at 7T using a T2-weighted sequence, resolution 115 × 115 × 230 µm. The code developed to create and manipulate the template has been refined into general procedures for registering small mammal brain MR images, available within a python module sammba-mri (SmAll-maMMals BrAin MRI; <a href="https://sammba-mri.github.io/">https://sammba-mri.github.io/</a>). The template was up-sampled to 91 µm isotropic for hand-segmentation of structures, and also used to create probability maps of grey matter, white matter and cerebro-spinal fluid.</p> <p>if used for publication please cite: </p> <p><strong>A 3D population-based brain atlas of the mouse lemur primate with examples of applications in aging studies and comparative anatomy</strong><br> Nachiket A Nadkarni, Salma Bougacha, Clément Garin, Marc Dhenain, Jean-Luc Picq<br> Jan 2019<br> <strong>NeuroImage</strong> 185, 85-95<br> DOI: 10.1016/J.NEUROIMAGE.2018.10.010<br> <a href="https://www.sciencedirect.com/science/article/pii/S1053811918319694">https://www.sciencedirect.com/science/article/pii/S1053811918319694</a></p>
Functional organization of the mouse lemur Primate Microcebus murinus : from multilevel validation to comparison with humans
<p>Brain network organization in the mouse lemur (Microcebus murinus) Primate.<br> (comparison with humans)<br> Archives contain:<br> <br> - Dictionary learning analysis in mouse lemurs and humans showing networks identified in these two species.<br> <br> - Cerebral templates from mouse lemurs and humans (MNI template). They can be used to localize networks.<br> <br> - A functional atlas of the mouse lemur brain issued from resting fMRI. Resting-state functional MR images were recorded from 14 mouse lemurs at 11.7 Tesla (2 time point per animal).<br> - An atlas from human brain (issued from <a href="http://www.gin.cnrs.fr/fr/outils/aal-aal2/">http://www.gin.cnrs.fr/fr/outils/aal-aal...</a>) that can be used to attribute human cerebral networks.<br> <br> - Templates, atlases and networks can be easily observed together using ITK-SNAP (<a href="http://www.itksnap.org/">http://www.itksnap.org/</a>).</p> <p>if used for publication please cite: </p> <p><strong>Resting state functional atlas and cerebral networks in mouse lemur primates at 11.7 Tesla</strong><br> <strong>Clément M Garin</strong>, Nachiket A Nadkarni, Brigitte Landeau, Gaël Chételat, Jean-Luc Picq, Salma Bougacha, Marc Dhenain<br> Feb 2021<br> <strong>NeuroImage</strong> 226, 117589<br> DOI: 10.1016/J.NEUROIMAGE.2020.117589<br> <a href="https://www.sciencedirect.com/science/article/pii/S1053811920310740">https://www.sciencedirect.com/science/article/pii/S1053811920310740</a></p>
Maternal and genetic correlations between morphology and physical performance traits in a small captive primate, Microcebus murinus
<p>Physical performance traits are key components of fitness and direct targets of selection. Maternal effects are important components of integrated phenotypes in a variety of species. Yet their contribution to variation in performance, and phenotypes closely associated with performance, remains poorly understood. We used an animal model approach to quantify the contribution of maternal effects to performance trait variation (in bite force and pull strength) and the relationships between performance and the relevant underlying morphology in <i>Microcebus murinus</i>. We show that bite force is heritable (h<sup>2</sup>~0.23), and that maternal effects are also important source of variation, resulting in a medium inclusive heritability (IH<sup>2</sup>~0.47). Grip strength presented a rather low and non-significant narrow-sense heritability suggesting a higher selective pressure on this trait. Genetic correlations between performance traits and their associated morphometric traits were significant and high (0.47 bite force-head width; 0.48 grip strength-radius length), as was the maternal correlation for bite force-head width (0.75). Further studies evaluating the heritability of performance for other taxa and the role of maternal effects are badly needed to better understand the drivers of variation in performance ultimately allowing for a better understanding of the importance of these types of traits in an evolutionary context.</p>
Fig. 3 in Seasonal variation in the abundance and distribution of ticks that parasitize Microcebus griseorufus at the BezàMahafaly Special Reserve, Madagascar
Fig. 3. Possible life cycle of H. lemuris. Peak activity for larvae occurs in May, but larvae may be found feeding into June and October. Larvae attach to Microcebus hosts and after a blood meal, fall off and molt into nymphs. Nymphs are active and feed on Microcebus throughout the dry season and likely feed on other lemurs during part of the wet season. Adult-stage ticks remain active during the wet season, feeding on larger-bodied lemurs, such as L. catta, and P. verreauxi. Engorged females fall off and lay eggs in leaf litter. It is possible that all four stages can diapause if no suitable hosts or conditions are found (gray dotted line). Mice or rats may also serve as hosts to larvae during the dry season.
Fig. 1. Monthly averages for A in Seasonal variation in the abundance and distribution of ticks that parasitize Microcebus griseorufus at the BezàMahafaly Special Reserve, Madagascar
Fig. 1. Monthly averages for A) tick intensity on mouse lemurs as it compares to B) rainfall and C) temperature, during the year-long study season. Shaded area indicates months included in the dry season. Environmental data were collected daily.
Fig. 2 in Seasonal variation in the abundance and distribution of ticks that parasitize Microcebus griseorufus at the BezàMahafaly Special Reserve, Madagascar
Fig. 2. Differences in infestation rates at Parcel 1 by A) sex B) substrate C) males and substrate and D) females and substrate. * indicates P <0.05, **P <0.01; ***P <0.001 and compares variables on the x-axis.
Fig. 6 in Differences in infection patterns of vector-borne blood-stage parasites of sympatric Malagasy primate species (Microcebus murinus, M. ravelobensis)
Fig. 6. Phylogenetic tree of 33 filarial nematode species constructed on the basis of partial COI sequences using the Maximum Likelihood method. The percentage of replicate trees in which the associated species clustered together in the bootstrap test (1000 replicates) is shown next to the branches. Branch lengths is measured in the number of substitutions per site. Thelazia callipaeda was included as an outgroup. The sequence of the present study is framed in red.
Fig. 5 in Differences in infection patterns of vector-borne blood-stage parasites of sympatric Malagasy primate species (Microcebus murinus, M. ravelobensis)
Fig. 5. Phylogenetic tree of Onchocercidae species constructed on the basis of partial ITS1 sequences using the Maximum Likelihood method. The percentage of replicate trees in which the associated species clustered together in the bootstrap test (1000 replicates) is shown next to the branches. Branch lengths is measured in the number of substitutions per site. The sequences of the present study are framed in red. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3 in Differences in infection patterns of vector-borne blood-stage parasites of sympatric Malagasy primate species (Microcebus murinus, M. ravelobensis)
Fig. 3. Number of samples (blood smears) per month. Microfilaria positive samples are shown in dark blue for M. murinus and dark brown for M. ravelobensis, microfilaria negative samples in light blue for M. murinus and light brown for M. ravelobensis. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Maternal and genetic correlations between morphology and physical performance traits in a small captive primate, Microcebus murinus
Open the record for dataset details and reuse information.
Ancient introgression in mouse lemurs (Microcebus:Cheirogaleidae) explains 20 years of phylogenetic uncertainty
<p>Mouse lemurs (genus <em>Microcebus</em>) are a clade of approximately 26 named species of small, nocturnal primates endemic to Madagascar. The genus radiated one and ten million years ago and is morphologically cryptic, with most species having been named within the past 20 years largely based on phylogenetic analysis of short fragments of mitochondrial data. More recent work has been focused on revisiting species designations with autosomal nuclear data using more sophisticated statistical approaches. The order of speciation events in <em>Microcebus </em>remains contentious, particularly with regard to the placement of the <em>M. ravelobensis </em>clade. We investigated support for previous phylogenetic hypotheses based on available whole-genome assemblies from six species and an outgroup. We recovered over 4,000 one-to-one orthologs from these assemblies and used concatenation and coalescent species tree methods to<em> </em>evaluate if differences between previous studies were due to methodological differences or to limitations from too few loci. Observed gene tree discordance was high with patterns inconsistent with incomplete lineage sorting alone. Therefore, we estimated phylogenetic networks to investigate ancient introgression events that may explain observed gene tree distributions and previous phylogenetic conflicts. A network model, invoking some role for introgressive hybridization in the early evolution of <em>Microcebus</em>, better characterizes phylogenetic relationships than does any binary species tree. Our results provide insights into the biogeographic history of a threatened and diverse group of primates while also highlighting an important role for phylogenetic network methods in resolving cases of phylogenetic uncertainty.</p>
Theropithecus gelada and Microcebus murinus TBC1D3 Orthologous Sequence
<p>Genomic Sequence of TBC1D3 orthologous regions in Theropithecus gelada hap1 and hap2 used for Guitart et al.2024 journal article: "<strong>Independent expansion, selection and hypervariability of the TBC1D3 gene family in humans</strong>" </p> <p>https://www.biorxiv.org/content/10.1101/2024.03.12.584650v1</p>
Data from: Comparative genomic analysis of the pheromone receptor Class 1 family (V1R) reveals extreme complexity in mouse lemurs (genus, Microcebus) and a chromosomal hotspot across mammals
<p><span>Sensory gene families are of special interest, both for what they can tell us about molecular evolution, and for what they imply as mediators of social communication. The vomeronasal type-1 receptors (V1Rs) have often been hypothesized as playing a fundamental role in driving or maintaining species boundaries given their likely function as mediators of intraspecific mate choice, particularly in nocturnal mammals. Here, we employ a comparative genomic approach for revealing patterns of V1R evolution within primates, with a special focus on the small-bodied nocturnal mouse and dwarf lemurs of Madagascar (genera <i>Microcebus</i> and <i>Cheirogaleus</i>, respectively). By doubling the existing genomic resources for strepsirrhine primates (i.e., the lemurs and lorises), we find that the highly speciose and morphologically cryptic mouse lemurs have experienced an elaborate proliferation of V1Rs that we argue is functionally related to their capacity for rapid lineage diversification. Contrary to a previous study that found equivalent degrees of V1R diversity in diurnal and nocturnal lemurs, our study finds a strong correlation between nocturnality and V1R elaboration, with nocturnal lemurs showing elaborate V1R repertoires and diurnal lemurs showing less diverse repertoires. Recognized subfamilies among V1Rs show unique signatures of diversifying positive selection, </span>as might be expected if they have each evolved to respond to specific stimuli<span>. Further, a detailed syntenic comparison of mouse lemurs with mouse (genus <i>Mus</i>) and other mammalian outgroups shows that orthologous mammalian subfamilies, predicted to be of ancient origin, tend to cluster in a densely populated region across syntenic chromosomes that we refer to as a V1R "hotspot."</span></p>
Data from: Structure of microhabitats used by Microcebus rufus across a heterogeneous landscape
Open the record for dataset details and reuse information.
Data from: Comparative genomic analysis of the pheromone receptor Class 1 family (V1R) reveals extreme complexity in mouse lemurs (genus, Microcebus) and a chromosomal hotspot across mammals
Open the record for dataset details and reuse information.
Ancient introgression in mouse lemurs (Microcebus:Cheirogaleidae) explains 20 years of phylogenetic uncertainty
Open the record for dataset details and reuse information.
F I G U R E 7 in Ecology and morphology of mouse lemurs (Microcebus spp.) in a hotspot of microendemism in northeastern Madagascar, with the description of a new species
F I G U R E 7 Outer morphology of Microcebus jonahi. (a) Drawing of an adult individual; (b) Habitus of adult female (paratype individual BD1); (c–e) Close‐ups of adult male (holotype B34). Illustration copyright by Stephen D. Nash/IUCN SSC Primate Specialist Group; used with permission. Photos by D. Schüssler
F I G U R E 6 in Ecology and morphology of mouse lemurs (Microcebus spp.) in a hotspot of microendemism in northeastern Madagascar, with the description of a new species
F I G U R E 6 Reproductive records for adult males (a) and females (b) of Microcebus spp. in northeastern Madagascar and presence of juvenile individuals (c) in the population
F I G U R E 5 in Ecology and morphology of mouse lemurs (Microcebus spp.) in a hotspot of microendemism in northeastern Madagascar, with the description of a new species
F I G U R E 5 Linear discriminant analysis including all morphometric parameters (except third toe length). All five linages can be distinguished statistically (Wilk's lambda = 0.005; F = 10.338; p <.001) with a misclassification rate of 12.8%. dia, Mantadia NP; vala, Ambavala
F I G U R E 4 in Ecology and morphology of mouse lemurs (Microcebus spp.) in a hotspot of microendemism in northeastern Madagascar, with the description of a new species
F I G U R E 4 Principal component analysis including all morphometric parameters (except third toe length) showing PC1/PC2 (left) and PC3/PC4 (right). Small (M. mittermeieri and M. lehilahytsara) and large (M. sp. #3 and M. macarthurii) lineages differ along PC1, with some differentiation of M. mittermeieri and M. lehilahytsara along both PC1 and PC2, whereas M. sp. #3 and M. macarthurii split along PC3. Clusters corresponding to the five lineages were significantly different from each other (PERMANOVA: F = 36.88; df = 77; p <.001). dia, Mantadia NP; PERMANOVA, permutational multivariate analysis of variances; vala, Ambavala
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.