Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5
datasets available to search
ShareScore release 0.9.0
Dataset results
5 results for “Mimulus lewisii”
Data from: The genetic basis of a rare flower color polymorphism in Mimulus lewisii provides insight to the evolutionary mutation spectrum
A long-standing question in evolutionary biology asks whether the genetic changes contributing to phenotypic evolution are predictable. Here, we identify a genetic change associated with segregating variation in flower color within a population of Mimulus lewisii. To determine whether these types of changes are predictable, we combined this information with data from other species to investigate whether the spectrum of mutations affecting flower color transitions differs based on the evolutionary time-scale since divergence. We used classic genetic techniques, along with gene expression and population genetic approaches, to identify the putative, loss-of-function mutation that generates rare, white flowers instead of the common, pink color in M. lewisii. We found that a frameshift mutation in an anthocyanin pathway gene is responsible for the white-flowered polymorphism found in this population of M. lewisii. Comparison of our results with data from other species reveals a broader spectrum of flower color mutations segregating within populations relative to those that fix between populations. These results suggest that the genetic basis of fixed differences in flower color may be predictable, but that for segregating variation is not.
CYCLOIDEA paralogs function redundantly to specify dorsal flower development in Mimulus lewisii (Phrymaceae)
<p><strong>Premise</strong>: Duplicated genes (paralogs) are abundant in plant genomes and their retention may influence the function of genetic programs and contribute to evolutionary novelty. How gene duplication affects genetic modules, and the forces that contribute to paralog retention are outstanding questions. The CYCLOIDEA(CYC)-dependent flower symmetry program is a model for understanding the evolution of gene duplication, providing multiple examples of paralog partitioning and novelty. However, a novel CYC gene lineage duplication event near the origin of Higher Core Lamiales (HCL) has received little attention.</p> <p><strong>Methods</strong>: To understand the evolutionary fate of duplicated HCL CYC2 genes, we determined the effects on flower symmetry of suppressing MlCYC2A and MlCYC2B expression using RNA interference (RNAi). We determined flower symmetry phenotypic effects in single and double silenced backgrounds and coupled this with expression surveys of MlCYC2A, MlCYC2B, and a putative downstream RADIALIS (MlRAD5) ortholog.</p> <p><strong>Key</strong> <strong>results</strong>: MlCYC2A and MlCYC2B jointly contribute to bilateral flower symmetry. MlCYC2B exhibits a clear dorsal flower identity function and may additionally function in carpel development. MlCYC2A functions in establishing dorsal petal shape. Further, our results suggest an MlCYC2A–MlCYC2B regulatory interaction which may affect pathway homeostasis.</p> <p><strong>Conclusions</strong>: Our results suggest that Higher Core Lamiales-specific CYC paralogs may be selectively retained for their joint contribution to bilateral flower symmetry, similar to the independently-derived CYC paralogs in the Lamiales model for bilateral flower symmetry research, <em>Antirrhinum</em> <em>majus</em> (snapdragon).</p>
Data from: The genetic basis of a rare flower color polymorphism in Mimulus lewisii provides insight to the evolutionary mutation spectrum
Open the record for dataset details and reuse information.
Data from: Chromosomal rearrangements directly cause underdominant F1 pollen sterility in Mimulus lewisii-M. cardinalis hybrids
Open the record for dataset details and reuse information.
CYCLOIDEA paralogs function redundantly to specify dorsal flower development in Mimulus lewisii (Phrymaceae)
Open the record for dataset details and reuse information.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.