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3 results for “Mimulus parishii”
Genotype, phenotype and linkage data for Mimulus parishii x M. cardinalis hybrid incompatibility study
<p>The evolution of genomic incompatibilities causing postzygotic barriers to hybridization is a key step in species divergence. Incompatibilities take two general forms – structural divergence between chromosomes leading to severe hybrid sterility in F<sub>1</sub> hybrids and epistatic interactions between genes causing reduced fitness of hybrid gametes or zygotes (Dobzhansky-Muller incompatibilities). Despite substantial recent progress in understanding the molecular mechanisms and evolutionary origins of both types of incompatibility, how each behaves across multiple generations of hybridization remains relatively unexplored. Here, we use genetic mapping in F<sub>2</sub> and RIL hybrid populations between the phenotypically divergent but naturally hybridizing monkeyflowers <em>Mimulus cardinalis</em> and <em>M. parishii</em> to characterize the genetic basis of hybrid incompatibility and examine its changing effects over multiple generations of experimental hybridization. In F<sub>2</sub>s, we found severe hybrid pollen inviability (< 50% reduction vs. parental genotypes) and pseudolinkage caused by a reciprocal translocation between Chromosomes 6 and 7 in the parental species. RILs retained excess heterozygosity around the translocation breakpoints, which caused substantial pollen inviability when interstitial crossovers had not created compatible heterokaryotypic configurations. Strong transmission ratio distortion and inter-chromosomal linkage disequilibrium in both F<sub>2</sub>s and RILs identified a novel two-locus genic incompatibility causing sex-independent gametophytic (haploid) lethality. The latter interaction eliminated three of the expected nine F<sub>2</sub> genotypic classes via F<sub>1</sub> gamete loss without detectable effects on the pollen number or viability of F<sub>2</sub> double heterozygotes. Along with the mapping of numerous milder incompatibilities, these key findings illuminate the complex genetics of plant hybrid breakdown and are an important step toward understanding the genomic consequences of natural hybridization in this model system.</p>
Floral phenotype data from Mimulus parishii x M. cardinalis hybrids
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Genotype, phenotype and linkage data for Mimulus parishii x M. cardinalis hybrid incompatibility study
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