Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
97
datasets available to search
ShareScore release 0.9.0
Dataset results
97 results for “Mycosis Fungoides”
Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in mycosis fungoides and Sezary syndrome
<p>T-cell non-Hodgkin's lymphomas (NHL) develop following transformation of tissue resident T-cells. We performed a meta-analysis of mutational catalogues derived from whole exome sequencing data from 403 patients with eight subtypes of T-cell NHL to identify mutational signatures and recurrent gene mutations associated with specific causal peaks within these signatures. Signature 1, indicative of age-related deamination, was prevalent across all T-cell NHL subtypes, reflecting the derivation of these malignancies from memory T-cell subsets. Adult T-cell leukemia-lymphoma (ATLL) was specifically associated with signature 17, which was found to strongly correlate with the IRF4 K59R mutation that is exclusive to ATLL. Signature 7, implicating UV exposure as a potential initiating factor was uniquely identified in cutaneous T-cell lymphoma, contributing 52% of the mutational burden in mycosis fungoides and 23% in Sezary syndrome. Importantly this UV signature was observed in CD4+ T-cells isolated from blood suggesting extensive re-circulation of these T-cells through both skin and blood and strongly implicating a role for UV in the pathogenesis of cutaneous T-cell lymphoma.</p>
Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome
ClinicalTrials.gov study NCT00047060. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma
ClinicalTrials.gov study NCT03063632. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Brentuximab Vedotin (SGN-35) in Patients With Mycosis Fungoides With Variable CD30 Expression Level
ClinicalTrials.gov study NCT01396070. IPD Sharing: NO. Countries: 1. Publications: 1.
Pembrolizumab in Treating Patients With Relapsed or Refractory Stage IB-IVB Mycosis Fungoides or Sezary Syndrome
ClinicalTrials.gov study NCT02243579. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Safety and Efficacy of Nitrogen Mustard in Treatment of Mycosis Fungoides
ClinicalTrials.gov study NCT00168064. IPD Sharing: Not stated. Countries: 1. Publications: 7.
FLASH [Fluorescent Light Activated Synthetic Hypericin] Clinical Study: Topical SGX301 (Synthetic Hypericin) for the Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides)
ClinicalTrials.gov study NCT02448381. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Low-dose (12 Gy) TSEBT+Vorinostat Versus Low-dose TSEBT Monotherapy in Mycosis Fungoides
ClinicalTrials.gov study NCT01187446. IPD Sharing: NO. Countries: 1. Publications: 2.
SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides
ClinicalTrials.gov study NCT03713320. IPD Sharing: NO. Countries: 8. Publications: 2.
Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in mycosis fungoides and Sezary syndrome
Open the record for dataset details and reuse information.
Evaluation of the International Society for Cutaneous Lymphoma Algorithm for the Diagnosis of Early Mycosis Fungoides
<p><strong>Supplementary Table 1.</strong> Clinicopathologic features and ISCL scores of cases included in this study</p> <p><strong>Supplementary Table 2.</strong> Curvilinear coordinates of ROC, sensitivity, specificity, and Youden’s index for CD2, CD3, CD5, and CD7 expression</p>
Tretinoin in Treating Patients With Mycosis Fungoides or Sezary Syndrome
ClinicalTrials.gov study NCT00002479. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Trial Assessing the Effect of Pembrolizumab Combined with Radiotherapy in Patients with Relapsed, Refractory, Specified Stages of Cutaneous T-cell Lymphoma (CTCL) Mycosis Fungoides (MF)/Sezary Syndr
ClinicalTrials.gov study NCT03385226. IPD Sharing: NO. Countries: 1. Publications: 1.
Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS)
ClinicalTrials.gov study NCT02953301. IPD Sharing: NO. Countries: 12. Publications: 2.
PUVA Maintenance Therapy in Mycosis Fungoides
ClinicalTrials.gov study NCT01686594. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome.
ClinicalTrials.gov study NCT04904146. IPD Sharing: NO. Countries: 1. Publications: 1.
SGN-35 in CD30-positive Lymphoproliferative Disorders (ALCL), Mycosis Fungoides (MF), and Extensive Lymphomatoid Papulosis (LyP)
ClinicalTrials.gov study NCT01352520. IPD Sharing: Not stated. Countries: 1. Publications: 1.
An Open Label Study to Evaluate the Safety and Efficacy of Mechlorethamine(MCH) 0.04% Formulation in Mycosis Fungoides
ClinicalTrials.gov study NCT00535470. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy of Doxycycline in the Treatment of Early Stages of Mycosis Fungoides
ClinicalTrials.gov study NCT03454945. IPD Sharing: NO. Countries: 1. Publications: 2.
Ultraviolet Light Therapy Using Methoxsalen With or Without Bexarotene in Treating Patients With Mycosis Fungoides
ClinicalTrials.gov study NCT00056056. IPD Sharing: Not stated. Countries: 13. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.