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Dataset results
192 results for “Myocardial cell”
Intracellular delivery of nitric oxide enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarction
<p>Cell therapy by autologous mesenchymal stem cells (MSCs) is a clinically acceptable strategy for treating various diseases. Unfortunately, the therapeutic efficacy is largely affected by the low quality of MSCs collected from patients. Herein, we showed that the gene expression of MSCs from patients with diabetes was differentially regulated compared to that of MSCs from healthy controls. Then, MSCs were genetically engineered to catalyse an NO prodrug to release NO intracellularly. Compared to extracellular NO conversion, intracellular NO delivery effectively prolonged survival and enhanced the paracrine function of MSCs, as demonstrated by in vitro and in vivo assays. The enhanced therapeutic efficacy of engineered MSCs combined with intracellular NO delivery was further confirmed in mouse and rat models of myocardial infarction, and a clinically relevant cell administration paradigm through secondary thoracotomy has been attempted.</p>
Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients
ClinicalTrials.gov study NCT02362646. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration
ClinicalTrials.gov study NCT01458405. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation
ClinicalTrials.gov study NCT01442129. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Intracellular delivery of nitric oxide enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarction
Open the record for dataset details and reuse information.
The supplementary materials of the article"Construction of myocardial patch with mesenchymal stem cells and poly (CL-co-TOSUO)/collagen scaffolds for myocardial infarction repair by coaxial electrospinning"
<p>The supplementary materials of "Construction of myocardial patch with mesenchymal stem cells and poly (CL-co-TOSUO)/collagen scaffolds for myocardial infarction repair by coaxial electrospinning" consist of three figures: Figure S1: The structure and the molecular characteristics of the elastic PCT from gel permeation chromatography; Figure S2: Time series photographs of the rats’ back skin following the subcutaneous transplantation of coaxial electrospun fibrous PCT/collagen scaffolds. Figure S3: Representative histopathological images of the rats' skin following the transplantation of PCT/collagen coaxial nanofibers scaffolds.</p>
Cell Therapy in Myocardial Infarction
ClinicalTrials.gov study NCT00350766. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Intracoronary Human Wharton's Jelly- Derived Mesenchymal Stem Cells (WJ-MSCs) Transfer in Patients With Acute Myocardial Infarction (AMI)
ClinicalTrials.gov study NCT01291329. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Bone Marrow Stem Cell Mobilisation Therapy for Acute Myocardial Infarction (AMI)(REVIVAL-2)
ClinicalTrials.gov study NCT00126100. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Safety & Efficacy of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia (ATHENA II)
ClinicalTrials.gov study NCT02052427. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Bone Marrow-Derived Stem Cell Transfer in Acute Myocardial Infarctions
ClinicalTrials.gov study NCT00264316. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Treatment of Myocardial Infarction With Bone Marrow Derived Stem Cells
ClinicalTrials.gov study NCT00275977. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Trial of Hematopoietic Stem Cells in Acute Myocardial Infarction
ClinicalTrials.gov study NCT00984178. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Umbilical Cord Mesenchymal Stem Cell Improve Cardiac Function on ST-elevation Myocardial Infarction (STEMI) Patients
ClinicalTrials.gov study NCT05935423. IPD Sharing: Not stated. Countries: 1. Publications: 7.
The Relationship of Change of Dendritic Cells Fractalkine and P-selectin Patients With Acute Myocardial Infarction
ClinicalTrials.gov study NCT02896543. IPD Sharing: NO. Countries: 1. Publications: 7.
Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Intra-Coronary Stem Cell Infusion-3-DES
ClinicalTrials.gov study NCT00291629. IPD Sharing: Not stated. Countries: 1. Publications: 1.
MesenchYmal STROMAL CELL Therapy in Patients With Chronic Myocardial Ischemia (MyStromalCell Trial)
ClinicalTrials.gov study NCT01449032. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Red Cell Distribution Width,,NT-proBNP and cTnT in Acute Myocardial Infraction Patient
ClinicalTrials.gov study NCT05595278. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
SWiss Multicenter Intracoronary Stem Cells Study in Acute Myocardial Infarction (SWISS-AMI)
ClinicalTrials.gov study NCT00355186. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Myocardial Infarction
ClinicalTrials.gov study NCT04056819. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.