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14 results for “Nanosuspensions”
Dataset for Formulation of minitablets with personalised dissolution profile by fluid-bed granulation of drug nanosuspensions
<p>Source data for all graphs in the manuscript titled "Formulation of minitablets with personalised dissolution profile by fluid-bed granulation of drug nanosuspensions" by Mutylo et al., submitted to International Journal of Pharmaceutics. The data sets contains values for particle size distributions, tablet uniformity, drug loading, and dissolution curves.</p>
Evaluation of Ivermectin Mucoadhesive Nanosuspension as Nasal Spray in Management of Early Covid-19
ClinicalTrials.gov study NCT04716569. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Role of Ivermectin Nanosuspension as Nasal Spray in Treatment of Persistant Post covid19 Anosmia
ClinicalTrials.gov study NCT04951362. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Figure 7 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 7 The in vitro release profile of Candesartan cilexetil-loaded nanosuspensions and Candesartan cilexetil powder at A. Dissolution medium phosphate buffer (pH 6.8) and B. Dissolution medium HCl buffer (pH 1.2). Data are represented as mean ± standard deviation of three independent experiments.
Figure 8 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 8 Particle size and EE % analysis of the Candesartan cilexetil-loaded nanosuspensions. A. Particle size and B.EE % over three months at 32 °C, 25 °C and 4 °C. Data are represented as mean ± standard deviation of three independent experiments. * p-value > 0.05.
Figure 4 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 4 The AFM images of the Candesartan cilexetil-loaded nanosuspensions. A. 3D AFM image of candesartan cilexetil-loaded nanosuspensions; B. 2D AFM image of candesartan cilexetil-loaded nanosuspensions.
Figure 6 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 6 The DSC thermogram of A. pure candesartan cilexetil; B. Candesartan cilexetil-loaded nanosuspensions; C. Candesartan cilexetil-free nanosuspensions; D.PVP K-30; E. HPMS E5; F.PXM 188.
Figure 5 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 5 FTIR spectrum of A. Pure candesartan cilexetil compound; B.PVP K-30 polymer; C.HPMC E5 polymer; D.PXM 188 polymer; E. Candesartan cilexetil-free nanosuspensions; and F. Candesartan cilexetil-loaded nanosuspensions.
Figure 3 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 3 Response surface 3D plots showing the effect of independent variables on the dependent variables via (a) particle size, (b) PDI, (c) EE%, and (d) DL% by Design-Expert® software.
Figure 1 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 1 Calibration curve of candesartan cilexetil in HCl buffer (pH 1.2). Candesartan cilexetil was dissolved in HCl buffer (pH 1.2) at a concentration of 5, 10, 20, 30 and 50 µg.ml-1, and the U.V. absorbance at λmax 254 nm was gained. Data are represented as mean ± standard deviation of 3 independent experiments.
Figure 2 from: Al-Edresi S, Albo Hamrah K, Al-Shaibani A (2024) Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility. Pharmacia 71: 1-13. https://doi.org/10.3897/pharmacia.71.e114943
Figure 2 Calibration curve of candesartan cilexetil in phosphate buffer (pH 6.8). Candesartan cilexetil was dissolved in phosphate buffer (pH 6.8) at a concentration of 5, 10, 20, 30 and 50 µg.ml-1, and the U.V. absorbance at λmax 254 nm was gained. Data are represented as mean ± standard deviation of 3 independent experiments.
A Study to Evaluate the Pharmacokinetic Effects of Different Storage Conditions for a Long-Acting Nanosuspension of Rilpivirine on Pharmacokinetics
ClinicalTrials.gov study NCT02547870. IPD Sharing: Not stated. Countries: 1. Publications: 0.
BP31510 (Ubidecarenone,USP) Nanosuspension for Intravenous Injection to Patients With Solid Tumors
ClinicalTrials.gov study NCT01957735. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study to Investigate the Effect of Different Particle Sizes on the Single-dose Pharmacokinetics of Rilpivirine After Intramuscular Injection of a Long-acting Nanosuspension in Healthy Participants
ClinicalTrials.gov study NCT03127189. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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