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Dataset results
45 results for “Neuromuscular Junction”
Confocal micrographs and complete dataset of neuromuscular junction morphology of pelvic limb muscles of the pig (Sus scrofa)
<p>This dataset entails the complete NMJ dataset for three pigs and the three muscles analysed for the publication "Comparative anatomy of the mammalian neuromuscular junction" (https://doi.org/10.1111/joa.13260). This includes spreadsheets (.csv) containing morphometric variables of neuromuscular junction morphology generated using NMJ-morph or aNMJ-morph, as well as muscle fibre diameter (MFD) data for completeness. The three muscles analysed are: extensor digitorum longus (EDL), peroneus longus (PL) and soleus (S). Data contains raw microscope images (.nd2), thresholded and cleaned images of pre- and post-synapse (.tif) and the thresholded and cleaned images of the intermediate muscle endplate (.tif) for the muscle soleus since the "aNMJ-morph" macro saves this intermediate image for measurement of endplate variables.</p> <p>The full data set description is in the readme_file.txt.</p>
Comparing Lower-concentration Dysport Treatment Targeted to the Neuromuscular Junction With Current Clinical Practice
ClinicalTrials.gov study NCT01682148. IPD Sharing: YES. Countries: 4. Publications: 1.
Effect of Tetanus on Neuromuscular Junction Monitor Performance in Pediatric Patients
ClinicalTrials.gov study NCT02498678. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Wirelessly steerable bioelectronic neuromuscular robots adapting neurocardiac junctions
Open the record for dataset details and reuse information.
Dataset of: Macros to Quantify Exosome release and Autophagy at the Neuromuscular Junction of Drosophila Melanogaster
<p>Dataset of the future paper "Macros to Quantify Exosome release and Autophagy at the Neuromuscular Junction of Drosophila Melanogaster". If you have any doubts I can be found in this email: <a href="mailto:irene.sanchez-mirasierra@u-bordeaux.fr">irene.sanchez-mirasierra@u-bordeaux.fr</a></p>
Evaluation of the NeuroMuscular Junction Using the Single Fiber Electromyography and Reliability of Train-Of-Four in Critically Ill Patients.
ClinicalTrials.gov study NCT03893058. IPD Sharing: UNDECIDED. Countries: 1. Publications: 26.
Data from: The extracellular and cytoplasmic domains of Syndecan cooperate postsynaptically to promote synapse growth at the Drosophila neuromuscular junction
The heparan sulfate proteoglycan (HSPG) Syndecan (Sdc) is a crucial regulator of synapse development and growth in both vertebrates and invertebrates. In Drosophila, Sdc binds via its extracellular heparan sulfate (HS) sidechains to the receptor protein tyrosine phosphatase LAR to promote the morphological growth of the neuromuscular junction (NMJ). To date, however, little else is known about the molecular mechanisms by which Sdc functions to promote synapse growth. Here we show that all detectable Sdc found at the NMJ is provided by the muscle, strongly suggesting a post-synaptic role for Sdc. We also show that both the cytoplasmic and extracellular domains of Sdc are required to promote synapse growth or to rescue Sdc loss of function. We report the results of a yeast two-hybrid screen using the cytoplasmic domains of Sdc as bait, and identify several novel candidate binding partners for the cytoplasmic domains of Sdc. Together, these studies provide new insight into the mechanism of Sdc function at the NMJ, and provide enticing future directions for further exploring how Sdc promotes synapse growth.
Data from: The extracellular and cytoplasmic domains of Syndecan cooperate postsynaptically to promote synapse growth at the Drosophila neuromuscular junction
Open the record for dataset details and reuse information.
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia [Aging-Rapamycin data set].
GEO Series GSE139204. Mus musculus. 71 samples. Type: Expression profiling by high throughput sequencing.
Gut microbiota depletion delays peripheral nerve development and impairs neuromuscular junction maturation
GEO Series GSE210649. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance
GEO Series GSE267913. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance (snRNA-Seq)
GEO Series GSE267910. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia [NMJ data set].
GEO Series GSE139209. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
Neuromuscular junction transcriptome analysis of spinal and bulbar muscular atrophy mice implicates sarcomere gene expression and calcium flux dysregulation in disease pathogenesis
GEO Series GSE296707. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs (RNA-Seq)
GEO Series GSE65508. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
The miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction (RT-PCR)
GEO Series GSE43944. Drosophila melanogaster. 6 samples. Type: Other.
LSMEM2, localized at the neuromuscular junction, modulates mitochondrial integration in skeletal muscles
GEO Series GSE285026. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice
GEO Series GSE249484. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
The growth factor FGF21 maintains neuromuscular junction through histone deacetylase HDAC4 in denervation-induced skeletal muscle atrophy
GEO Series GSE303861. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
The miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction
GEO Series GSE43945. Drosophila melanogaster. 9 samples. Type: Other; Non-coding RNA profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.