Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
66
datasets available to search
ShareScore release 0.9.0
Dataset results
66 results for “Norovirus”
Murine norovirus virulence factor 1 (VF1) protein contributes to viral fitness during persistent infection [Primary data]
<p>Primary data underlying journal article titled "<strong>Murine norovirus virulence factor 1 (VF1) protein contributes to viral fitness during persistent infection</strong>"</p>
Benchmarking bioinformatic tools for amplicon-based sequencing of norovirus
<p>This repository contains associated datasets and accession numbers for a study entitled '<strong>Benchmarking bioinformatic tools for amplicon-based sequencing of norovirus'</strong>. The scripts for this project can be found on the GitHub project<a href="https://github.com/ahfitzpa/Benchmarking-bioinformatics-norovirus-amplicons"> page</a>. </p> <p>Expected composition tsv files are the OTU tables for each simulation performed (001-010). OTU IDs in this case are the expected taxonomy with the associated accession numbers. Samples are numbered 1-40, including the simulation number. Expected sequences fasta files contain the sequences used as input for each simulation, without primers or Illumina adapter sequences.</p> <p>Amplicons were generated using the following primers:</p> <p><strong>GI Primers </strong><br> GISKF: CTG CCC GAA TTY GTA AAT GA 4<br> GISKR: CCA ACC CAR CCA TTR TAC A 5<br> <br> <strong>GII Primers </strong><br> G2SKF: CNT GGG AGG GCG ATC GCAA 8<br> G2SKR: CCR CCN GCA TRH CCR TTR TAC AT</p> <p>In this study, three databases and multiple classifiers were compared. Here we include the taxonomy and fasta files for each database; noronet =NoroNet RIVM, calicinet= HuCat CDC and custom, randomly generated database. Fasta files for the classifiers include the GI/GII primers listed above in a 5-3 orientation. </p> <p>The tags.txt file contains the Illumina adapters used for the simulation component of the study.</p>
Norovirus Bivalent-Vaccine Efficacy Study
ClinicalTrials.gov study NCT01609257. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent VLP Vaccine
ClinicalTrials.gov study NCT02038907. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-Like Particle (VLP) Vaccine in Children
ClinicalTrials.gov study NCT02153112. IPD Sharing: YES. Countries: 3. Publications: 1.
Bivalent Norovirus Vaccine Study
ClinicalTrials.gov study NCT01168401. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Safety and Immunogenicity of Norovirus Bivalent Virus-Like Particle Vaccine in Healthy Adults
ClinicalTrials.gov study NCT02142504. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Serologic Assay Validation, Proficiency Testing, Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-Like Particle Vaccine
ClinicalTrials.gov study NCT02475278. IPD Sharing: Not stated. Countries: 1. Publications: 3.
NNITS-Nitazoxanide for Norovirus in Transplant Patients Study
ClinicalTrials.gov study NCT03395405. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Long-Term Immunogenicity of the Norovirus GI.1/GII.4 Bivalent Virus-like Particle (VLP) Vaccine (NoV Vaccine) in Adults
ClinicalTrials.gov study NCT03039790. IPD Sharing: YES. Countries: 2. Publications: 0.
Efficacy and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-like Particle Vaccine in Adults
ClinicalTrials.gov study NCT02669121. IPD Sharing: YES. Countries: 1. Publications: 0.
Infectivity of Norovirus in Shellfish Treated With High Hydrostatic Pressure Processing-Human Challenge Study
ClinicalTrials.gov study NCT00674336. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Phase 1 Placebo-controlled, Randomized Trial of an Adenoviral-vector Based Norovirus Vaccine
ClinicalTrials.gov study NCT02868073. IPD Sharing: NO. Countries: 1. Publications: 1.
Infectivity of Norovirus in Groundwater-Human Challenge Study
ClinicalTrials.gov study NCT00313404. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Susceptibility of Human Volunteers With Different Histo-Blood With Different Histo-Blood Group Antigens to Norovirus
ClinicalTrials.gov study NCT01322503. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Secondary Lactose Intolerance Due to Chronic Norovirus Infection
ClinicalTrials.gov study NCT01840891. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Recombinant, Bivalent, Norovirus Vaccine Study
ClinicalTrials.gov study NCT05508178. IPD Sharing: NO. Countries: 1. Publications: 2.
Optimal Human Dose for GII.2 Norovirus (Snow Mountain) Challenge Studies
ClinicalTrials.gov study NCT02473224. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Vomiting as a symptom and transmission risk in norovirus illness: evidence from human challenge studies
Background: In the US, noroviruses are estimated to cause 21 million cases annually with economic losses reaching $2 billion. Outbreak investigations frequently implicate vomiting as a major transmission risk. However, little is known about the characteristics of vomiting as a symptom or the amount of virus present in emesis. Methodology and Principal Findings: Emesis samples and symptomology data were obtained from previous norovirus human challenge studies with GI.1 Norwalk virus, GII.2 Snow Mountain virus, and a pilot study with GII.1 Hawaii virus. Viral titers in emesis were determined using strain-specific quantitative RT-PCR. In all four studies, vomiting was common with 40–100% of infected subjects vomiting at least once. However, only 45% of subjects with vomiting also had diarrhea. Most of the emesis samples had detectable virus and the mean viral titers were 8.0 x 105 and 3.9 x 104 genomic equivalent copies (GEC)/ml for GI and GII viruses, respectively (p = 0.02). Sample pH was correlated with GII.2 Snow Mountain virus detection. Conclusions and Significance: Half of all subjects with symptomatic infection experienced vomiting and the average subject shed 1.7 x 108 GEC in emesis. Unlike shedding through stool, vomiting is more likely to result in significant environmental contamination, leading to transmission through fomites and airborne droplets. This quantitative data will be critical for risk assessment studies to further understand norovirus transmission and develop effective control measures. The correlation between sample pH and virus detection is consistent with a single site of virus replication in the small intestine and stomach contents becoming contaminated by intestinal reflux. Additionally, the frequency of vomiting without concurrent diarrhea suggests that epidemiology studies that enroll subjects based on the presence of diarrhea may be significantly underestimating the true burden of norovirus disease.
Phase I Norovirus Challenge Model
ClinicalTrials.gov study NCT04174560. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.