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4 results for “Notophthalmus”

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dryad40/100

Effects of exogenous elevation of corticosterone on immunity and the skin microbiome of Eastern Newts (Notophthalmus viridescens): Data & R scripts

<p>The amphibian chytrid fungus, <em>Batrachochytrium</em> <em>salamandrivorans</em> (<em>Bsal</em>) threatens salamander biodiversity. The factors underlying <em>Bsal</em> susceptibility may include glucocorticoid hormones (GCs). The effects of GCs on immunity and disease susceptibility are well studied in mammals, but less is known in other groups, including salamanders. We used <em>Notophthalmus</em> <em>viridescens</em> (Eastern Newts) to test the hypothesis that GCs modulate salamander immunity. We first determined the dose required to elevate corticosterone (CORT; primary GC in amphibians) to physiologically relevant levels. We then measured immunity (neutrophil-lymphocyte ratios, plasma bacterial killing ability [BKA], skin microbiome, splenocytes, melanomacrophage centers [MMCs])  and overall health in newts following treatment with CORT or an oil vehicle control. Treatments were repeated for a short (2 treatments over 5 days) or long (18 treatments over 26 days) time period. Contrary to our predictions, most immune and health parameters were similar for CORT and oil-treated newts. Surprisingly, differences in BKA, skin microbiome, and MMCs were observed between newts subjected to short and long-term treatments, regardless of treatment type (CORT, oil vehicle). Taken together, CORT does not appear to be a major factor contributing to immunity in Eastern Newts, although more studies examining additional immune factors are necessary.</p>

opencc-zeroNov 2022View details →
dryad40/100

Effects of exogenous elevation of corticosterone on immunity and the skin microbiome of Eastern Newts (Notophthalmus viridescens): Data & R scripts

Open the record for dataset details and reuse information.

publicDec 2022View details →
geo24/100

Comparative transcriptome analysis of transgenic Drosophila misexpressing novel Notophthalmus viridescens (newt) genes

GEO Series GSE134348. Drosophila melanogaster. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo24/100

Microarray Analysis of microRNA Expression during Notophthalmus viridescens (red-spotted newt) heart regeneration

GEO Series GSE44547. Notophthalmus viridescens; Danio rerio; Pipidae; Homo sapiens. 3 samples. Type: Non-coding RNA profiling by array.

openGEO-OpenSep 2013View details →

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Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

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OpenNeuro

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neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record