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ShareScore release 0.9.0
Dataset results
39 results for “OXPHOS”
PubChem Data Mining of OXPHOS inhibitors: scripts, data, and models
<p>README doc, source, and data files from PubChem data mining project to identify OXPHOS inhibitory chemotypes.</p>
Data for: Chronic stress hinders sensory axon regeneration via impairing mitochondrial cristae and OXPHOS
<p>Spinal cord injury (SCI) often leads to physical limitations, chronic pain, significant life changes, and social isolation, increasing the risk of chronic psychological stress such as anxiety and depression. Despite the recognition of the negative effects of chronic stress on SCI recovery, the mechanisms linking stress and regeneration are not fully understood. In this study, we examined the impact of chronic stress on primary sensory axon regeneration in a mouse model of preconditioning lesions. Our findings showed that chronic stress caused mitochondrial damage and energy crisis within primary sensory neurons, hindering the regrowth of their central axons. The stress hormone corticosterone was identified as a critical factor in this process, impacting satellite glial cells instead of neurons by suppressing Kir4.1 expression and leading to increased neuronal hyperactivity and elevated ROS levels. These high levels of ROS altered the shape of the mitochondrial cristae and disrupted ATP production, which is essential for powering axonal regeneration. Our results highlight the importance of addressing psychological stress in SCI patients to promote sensory-motor rehabilitation.</p>
Data for: Chronic stress hinders sensory axon regeneration via impairing mitochondrial cristae and OXPHOS
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Muscle OXPHOS and Nutrient Homeostasis
ClinicalTrials.gov study NCT02920671. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors
ClinicalTrials.gov study NCT06819475. IPD Sharing: YES. Countries: 1. Publications: 0.
Data from: Evolutionary implications of mitochondrial genetic variation: Mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies
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Dysfunctions in nonsense-mediated decay, protein homeostasis, OXPHOS function, and brain connectivity in ALS-FUS mice with cognitive deficits
GEO Series GSE157713. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Voluntary running and IV nicotinamide riboside synergise to boost mouse skeletal muscle NAD+ without impacting OXPHOS capacity or insulin sensitivity
GEO Series GSE194193. Mus musculus. 62 samples. Type: Expression profiling by high throughput sequencing.
CD52 and OXPHOS - potential targets in ibrutinib treated mantle cell lymphoma
GEO Series GSE214725. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
OXPHOS driven by glycolysis through the malate aspartate shuttle is required for cardiomyocyte re-differentiation and long-term fish heart regeneration [WT_ZF_strain_RNAseq]
GEO Series GSE234934. Danio rerio. 61 samples. Type: Expression profiling by high throughput sequencing.
Enhanced hippocampal neurogenesis mediated by PGC-1α-activated OXPHOS after neonatal subclinical dose of Propofol exposure revealed by single-nuclei transcriptomic profiling
GEO Series GSE186216. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
OXPHOS bioenergetic compensation does not explain disease penetrance in Leber hereditary optic neuropathy
GEO Series GSE144914. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos
GEO Series GSE146696. Danio rerio. 48 samples. Type: Expression profiling by array.
OXPHOS Promotes Apoptotic Resistance and Persistence in TH17 cells
GEO Series GSE185478. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiles of wild-type and PERK-deficient cells during activation of OXPHOS
GEO Series GSE113572. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
MGA deletion leads to Richter's transformation via modulation of mitochondrial OXPHOS
GEO Series GSE263238. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
GEO Series GSE130906. Homo sapiens. 3 samples. Type: Other.
Enhanced hippocampal neurogenesis mediated by PGC-1α-activated OXPHOS after neonatal low-dose Propofol exposure
GEO Series GSE200968. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
PARKIN is not required to sustain OXPHOS function in adult mammalian tissues
GEO Series GSE263057. Mus musculus. 142 samples. Type: Expression profiling by high throughput sequencing.
OXPHOS deficiency activates global adaptation pathways to maintain mitochondrial membrane potential
GEO Series GSE162197. Saccharomyces cerevisiae W303. 86 samples. Type: Expression profiling by high throughput sequencing; Other.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.