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25 results for “Optimal vaccination”
Associated code and data for "Multi-level computational modeling of anti-cancer dendritic cell vaccination utilized to select molecular targets for therapy optimization (doi: 10.3389/fcell.2021.74635)"
<p>This deposit contains the data, code, and analysis to reproduce the results in the manuscript - Lai X, Keller C, Santos-Rosales G, Schaft N, Dörrie J, Vera J. Multi-level computational modeling of anti-cancer dendritic cell vaccination utilized to select molecular targets for therapy optimization. Frontiers in Cell and Developmental Biolology. 2022; 9:746359; <a href="https://www.researchgate.net/publication/358461035_Multi-Level_Computational_Modeling_of_Anti-Cancer_Dendritic_Cell_Vaccination_Utilized_to_Select_Molecular_Targets_for_Therapy_Optimization">doi:10.3389/fcell.2021.746359</a>.</p> <p>If you have used the code for your research, please cite the original publication. Thank you very much.</p> <p> </p>
Optimal vaccination at high reproductive numbers: sharp transitions and counterintuitive allocations
Optimization of vaccine allocations among different segments of a heterogeneous population is important for enhancing the effectiveness of vaccination campaigns in reducing the burden of epidemics. Intuitively, it would seem that allocations designed to minimize infections should prioritize those with the highest risk of being infected and infecting others. This prescription is well supported by vaccination theory, e.g. when the vaccination campaign aims to reach herd immunity. In this work, we show, however, that for vaccines providing partial protection (leaky vaccines) and for sufficiently high values of the basic reproduction number, intuition is overturned: the optimal allocation minimizing the number of infections prioritizes the vaccination of those who are least likely to be infected. The work combines numerical investigations, asymptotic analysis for a general model, and complete mathematical analysis in a two-group model. The results point to important considerations in managing vaccination campaigns for infections with high transmissibility.
Optimal vaccination at high reproductive numbers: sharp transitions and counterintuitive allocations
Open the record for dataset details and reuse information.
Data from "Optimizing the baiting strategy for oral vaccine delivery to wild boar"
<p>Data from the paper "Optimization of the baiting strategy for the administration of oral vaccines to wild boar". These data are from experiments done in field work based on the baiting preference of different animal species.</p>
Increasing Optimal Use of HPV Vaccination in Primary Care
ClinicalTrials.gov study NCT04180462. IPD Sharing: NO. Countries: 1. Publications: 0.
Optimizing HPV Vaccine Introduction in Shanghai, China
ClinicalTrials.gov study NCT03972813. IPD Sharing: YES. Countries: 1. Publications: 1.
Presumptively Initiating Vaccines and Optimizing Talk With Motivational Interviewing (PIVOT With MI)
ClinicalTrials.gov study NCT03885232. IPD Sharing: NO. Countries: 1. Publications: 2.
Optimizing Influenza Vaccination in Surgical Oncology Patients
ClinicalTrials.gov study NCT01698177. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Immunogenicity and Safety of Fractional Booster Dose of COVID-19 Vaccines Available for Use in Pakistan/Brazil: A Phase 4 Dose-optimizing Trial
ClinicalTrials.gov study NCT05343871. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Establishing Optimal Number of Doses for HPV Vaccination in Children and Adolescents Living With HIV, OPTIMO Trial
ClinicalTrials.gov study NCT04265950. IPD Sharing: NO. Countries: 3. Publications: 1.
Optimal Timing of Zoster Vaccine After Zoster Illness
ClinicalTrials.gov study NCT02704572. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults
ClinicalTrials.gov study NCT02601716. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Optimal Timing of Zoster Vaccine After Hematopoietic Stem Cell Transplantation
ClinicalTrials.gov study NCT03192319. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Sequential Optimization of Dose and Schedule of PfSPZ Vaccine
ClinicalTrials.gov study NCT02704533. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Research on Optimal Immunization Strategy of Hepatitis B Vaccine in Chronic Kidney Disease Population
ClinicalTrials.gov study NCT03962881. IPD Sharing: NO. Countries: 1. Publications: 3.
Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea
ClinicalTrials.gov study NCT03590340. IPD Sharing: NO. Countries: 1. Publications: 1.
Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects
ClinicalTrials.gov study NCT03382977. IPD Sharing: YES. Countries: 1. Publications: 0.
Immunogenicity, Safety and Optimal Dose Finding Study of Recombinant Influenza H5N1 Vaccine in Healthy Young Adults
ClinicalTrials.gov study NCT00980447. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Optimal Timing of Vaccination in Pregnancy
ClinicalTrials.gov study NCT06466629. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Optimizing Hepatitis B Vaccine Response Through the Use of a Topical Immune Modulator
ClinicalTrials.gov study NCT00175435. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.