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319 results for “PBMCs”
Bulk RNA-Seq PBMC data of SLE patients and healthy volunteers/ profiling of 29 individual immune cell types as well as PBMCs of healthy donors
<p>This Zenodo project contains processed gene expression data from two publicly available data sets. It includes the gene expression data of peripheral blood mononuclear cells (PBMCs) of systemic lupus erythematosus (SLE) patients as well as healthy volunteers (GSE122459). The project also comprises the bulk RNA-Seq profiling of 29 immune cell types as well as PBMCs of healthy individuals (GSE107011). In both cases, the raw RNA-Seq data was downloaded, aligned and processed. The gene expression data is available in form of a count matrix (GSE107011) or count matrix and transcript-per-million (TPM) values (GSE122459). For the latter, an annotation file is attached. Further details are provided in the information file. </p>
Proteome of peripheral mononuclear cells (PBMCs) from asymptomatic malaria and uninfected individuals and the ensuing malaria episodes
<p>Cumulative malaria parasite exposure in endemic regions often results in the acquisition of partial immunity and asymptomatic infections. There is limited information on how host-parasite interactions mediate maintenance of chronic symptomless infections that sustain malaria transmission. Here, we have determined the gene expression profiles of the parasite population and the corresponding host peripheral blood mononuclear cells (PBMCs) from 21 children (<15 years). We compared children who were defined as uninfected, asymptomatic and those with febrile malaria. Children with asymptomatic infections had a parasite transcriptional profile characterized by a bias toward trophozoite stage (~12 hours-post invasion) parasites and low parasite levels, while earlier ring stage parasites were characteristic of febrile malaria. The host response of asymptomatic children was characterized by downregulated transcription of genes associated with inflammatory responses, compared to children with febrile malaria. Interestingly, the host responses during febrile infections that followed an asymptomatic infection featured stronger inflammatory responses, whereas the febrile host responses from previously uninfected children featured increased humoral immune responses. The priming effect of prior asymptomatic infection may explain the blunted acquisition of antibody responses seen to malaria antigens following natural exposure or vaccination in malaria endemic areas.</p>
Proteome of peripheral mononuclear cells (PBMCs) from asymptomatic malaria and uninfected individuals and the ensuing malaria episodes
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SingleCellExperiment Object for Kang et al., 2018 PBMCs data
<p>Kang et al., 2018 lupus PBMC data as SingleCellExperiment; also available under https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE96583. Converted from an AnnData object from https://github.com/theislab/pertpy</p>
Seurat_object_merged_PBMCs
<p>This dataset includes a Seurat object consisting of the merged count data from PBMCs of patients included in the study "Genomic Insights into Pediatric Intestinal Inflammatory and Eosinophilic Disorders using Single-sell RNA-sequencing." This is the unfiltered, unmapped data after reading the CellRanger count data into Seurat. It contains singlets identified via demuxlet. Barcodes that were not mapped to a genotype or were found not to be singlets were removed.</p>
Gene Expression Profiling in PBMCs as a Tool for Prediction of Anakinra Responsiveness in Rheumatoid Arthritis
ClinicalTrials.gov study NCT00213538. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies
ClinicalTrials.gov study NCT00067054. IPD Sharing: Not stated. Countries: 2. Publications: 4.
Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serum Biomarkers and on PBMCs in Breast Cancer Surgery
ClinicalTrials.gov study NCT03005860. IPD Sharing: NO. Countries: 1. Publications: 15.
Data from: Bulk-seq results from peripheral blood mononuclear cells (PBMCs) of VKH patients and proteomic profiling of shAPOE-transduced HMC3 cells were employed to uncover potential downstream targets of APOE
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Lipidomic dataset on PBMCS and plasma of obese patient with or without dysglycemia
<p>Lipidomic dataset on PBMCS and plasma of obese patient with or without dysglycemia.</p>
Analysis of Cellular Kinases and Aging in PBMCs and Colorectal Tissue
ClinicalTrials.gov study NCT06132386. IPD Sharing: NO. Countries: 1. Publications: 0.
Single-cell analysis of human PBMCs in healthy and type 2 diabetes populations: Dysregulated immune networks in type 2 diabetes unveiled through single-cell profiling
GEO Series GSE268210. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing; Other.
Analysis of single-cell RNA-seq data from human PBMCs and from in vitro cultures of human cord blood CD34+ progenitors encompassing different DC types
GEO Series GSE115405. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Comparative analysis of gene expression between PBMCs from TB patients and healthy individuals.
GEO Series GSE148171. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Single-cell 5' RNA sequencing of Bactrian camel PBMCs
GEO Series GSE238082. Camelus bactrianus. 8 samples. Type: Expression profiling by high throughput sequencing.
The effects of Cryopreservation on PBMCs transcriptome profile
GEO Series GSE304704. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA-sequencing of PBMCs from SAVI patients reveals disease-associated monocytes with elevated integrated stress response I
GEO Series GSE226572. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profile of human memory B cells isolated from lung, lung-draining lymph node and PBMCs
GEO Series GSE186010. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
RNAseq of TLR agonist and SLE Immune complex stimulated SLE patient PBMCs with and without depletion of pDCs with CSL362
GEO Series GSE231686. Homo sapiens. 288 samples. Type: Expression profiling by high throughput sequencing.
Single cell RNA seq of intestinal immune cells and PBMCs in salt-sensitive hypertension
GEO Series GSE293074. Rattus norvegicus. 14 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.