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60 results for “PREVENTIVE MEDICINE”
Measuring platelet function: new strategies for precision medicine to prevent thrombosis - Prof Jon Gibbins (University of Reading)
<p>This video is the third talk from our two day Future Blood Testing: Challenges & Opportunities Event that took place on the 13/09/2022.</p> <p>Measuring platelet function: new strategies for precision medicine to prevent thrombosis - Prof Jon Gibbins (University of Reading).</p> <p>Bio: Jon Gibbins is Professor of Cell Biology within the School of Biological Sciences at the University and is Director of the Institute for Cardiovascular and Metabolic Research. He is a graduate of the University, obtaining a degree in Pathobiology with Chemistry in 1991 and a PhD in Molecular Endocrinology in 1995. Following a period of postdoctoral research at the Oxford University, he returned to Reading in 1998 as a lecturer. Jon has established an internationally leading research group that studies blood clotting, with a particular focus on the development of more effective clinical strategies for the prevention and treatment of heart attacks and strokes, and thrombosis associated with infection. Jon values greatly working in an active, engaging and successful school, in which all aspects of biology are represented, and he champions cross-disciplinary working to approach today’s most challenging and pressing questions in new ways. He believes strongly in widening participation and improving levels of equity, diversity and inclusion across our institution.</p> <p>Further details on this event can be found at: https://futurebloodtesting.org/event/13-14-09-2022/</p> <p>This video is an output from the Future Blood Testing Network which is funded by EPSRC under Grant Number EP/W000652/1</p> <p>YouTube Link: https://youtu.be/8vJZ_WO-dvk</p>
Preventative medicine? Examining prophylactic effects of a sunflower pollen diet in Bombus impatiens
<p>The widespread decline of pollinator populations is of concern for both natural and agricultural ecosystems. Pathogens have been identified as a major contributor to the decline of some bee species, making understanding host-pathogen dynamics a crucial area of research. Sunflower pollen (<em>Helianthus annuus</em>) dramatically and consistently reduces infection by a prevalent gut pathogen, <em>Crithidia bombi</em>, in the common eastern bumble bee (<em>Bombus impatiens</em>), when consumed by bees post-infection, but we do not know if sunflower can confer protection when consumed before exposure. We asked whether feeding bumble bees sunflower pollen diets before pathogen exposure decreases <em>Crithidia</em> infection compared to buckwheat pollen (<em>Fagopyrum esculentum</em>). Buckwheat pollen was used as a comparison since it has a similar protein concentration as sunflower pollen, but results in high <em>Crithidia</em> counts when consumed post-infection. Bumble bees were fed sunflower or buckwheat pollen for seven days, inoculated with <em>Crithidia</em>, and then fed a wildflower pollen control diet for seven more days before assessing infection. We found that consuming a sunflower pollen diet before inoculation did not reduce <em>Crithidia</em> cell counts compared to buckwheat pollen. Further, bumble bee survival and consumption of sucrose solution and pollen did not differ between these diets. The results show no evidence of sunflower pollen providing prophylactic resistance against <em>Crithidia bombi </em>infection, indicating that the timing at which sunflower pollen is consumed relative to exposure has important consequences for infection.</p>
Preventative medicine? Examining prophylactic effects of a sunflower pollen diet in Bombus impatiens
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Looking in the medicine cabinet: methods for using real-world data to assess the impact of measles, mumps and rubella (MMR) and recombinant adjuvanted varicella-zoster vaccines on coronavirus disease 2019 (COVID-19) prevention and case fatality
<p>Supplementary File S1. 20210712_vx_off_target_pubdraft_S1 (Tables, Graphs and scripts associated with publication)</p> <p>Data file 1. Basic_Analysis.R (descriptive analysis script in R, for use with cleaned data files 3, 4 and 6)<br> Data file 2. Cleaning (Script demonstrating how Cerner data was cleaned upon download)<br> Data file 3. COVID_all_cleaned (CSV file with all COVID+ subjects in Cerner institutions)<br> Data file 4. COVID_mmr_data_cleaned (CSV file with COVID+ patients between 25-64 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, MMR vaccine history and mortality outcomes)<br> Data file 5. COVID_mmr_data_matched (CSV file matching MMR vaccine-exposed cases to controls based on propensity scores)<br> Data file 6. COVID_zoster_data_cleaned (CSV file with COVID+ patients above 50 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, zoster vaccine history and mortality outcomes)<br> Data file 7. COVID_zoster_data_matched (CSV file matching zoster vaccine-exposed cases to controls based on propensity scores)<br> Data file 8. General_25_64_data_cleaned (CSV file, all patients in Cerner institutions between 25 – 64 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, MMR vaccine history, SARS-CoV-2 infection and COVID-19 mortality outcomes ).<br> Data file 9. General_over50_data_cleaned (CSV file, all patients in Cerner institutions above 50 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, zoster vaccine history, SARS-CoV-2 infection and COVID-19 mortality outcomes).<br> Data file 10. Included_tenants (CSV file, institution IDs whose contributed cases comprise at least 0.5% of the aggregate sample size).<br> Data file 11. MMR_ps (R script to run for MMR-related files analysis)<br> Data file 12. Zoster_ps (R script to run for zoster-related files analysis)</p>
SomPsyNet - Prevention of Psychosocial Distress Consequences in Somatic Medicine: a Model for Collaborative Care
ClinicalTrials.gov study NCT04269005. IPD Sharing: YES. Countries: 1. Publications: 3.
Medicinal Nicotine for Preventing Stress Induced Craving and Withdrawal Symptoms
ClinicalTrials.gov study NCT01522963. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Use of medicinal plants for COVID-19 prevention and respiratory symptom treatment during the pandemic in Cusco, Peru: A cross-sectional survey
<p><b>Background:</b> The burden of the COVID-19 pandemic in Peru has led to people seeking alternative treatments as preventives and treatment options such as medicinal plants. This study aimed to assess factors associated with the use of medicinal plants as preventive or treatment of respiratory symptom related to COVID-19 during the pandemic in Cusco, Peru.<b> </b></p> <p><b>Method: </b>A web-based cross-sectional study was conducted on general public (20- to 70-year-old) from August 31 to September 20, 2020. Data were collected using a structured questionnaire via Google Forms, it consisted of an 11-item questionnaire that was developed and validated by expert judgment using Aiken's V (Aiken's V > 0.9). Both descriptive statistics and bivariate followed by multivariable logistic regression analyses were conducted to assess factors associated with the use of medicinal plants for COVID-19 prevention and respiratory symptom treatment during the pandemic. Prevalence ratios (PR) with 95% Confidence Interval (CI), and a P-value of 0.05 was used to determine statistical significance.</p> <p><b>Results: </b>A total of 1,747 respondents participated in the study, 80.2% reported that they used medicinal plants as preventives, while 71% reported that they used them to treat respiratory symptoms. At least, 24% of respondents used medicinal plants when presenting with two or more respiratory symptoms, while at least 11% used plants for malaise. For treatment or prevention, the multivariate analysis showed that most respondents used eucalyptus (p < 0.001 for both), ginger (p < 0.022 for both), spiked pepper (p < 0.003 for both), garlic (p = 0.023 for prevention), and chamomile (p = 0.011 for treatment). The respondents with COVID-19 (p < 0.001), at older ages (p = 0.046), and with a family member or friend who had COVID-19 (p < 0.001) used more plants for prevention. However, the respondents with technical or higher education used less plants for treatment (p < 0.001).</p> <p><b>Conclusion: </b>There was a significant use of medicinal plants for both prevention and treatment, which was associated with several population characteristics and whether respondents had COVID-19.</p>
Development of Health Management Model for Chinese Medical Preventive Medicine
ClinicalTrials.gov study NCT03640169. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study on the Prevention of Dermal Toxicity Caused by Regorafenib by Traditional Chinese Medicine TDX105
ClinicalTrials.gov study NCT05289726. IPD Sharing: NO. Countries: 1. Publications: 1.
Transfusion Medicine - Prevention of Bedside Errors
ClinicalTrials.gov study NCT00127556. IPD Sharing: Not stated. Countries: 6. Publications: 1.
Efficacy of Chinese Herbal Medicine to Prevent and Treat COVID-19 Close Contacts
ClinicalTrials.gov study NCT05269511. IPD Sharing: YES. Countries: 1. Publications: 1.
Efficacy of an Active Geriatric Evaluation for Geriatric Syndromes to Prevent Functional Decline in Family Medicine
ClinicalTrials.gov study NCT02618291. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Treatment and Prevention of Traditional Chinese Medicines (TCMs) on COVID-19 Infection
ClinicalTrials.gov study NCT04251871. IPD Sharing: NO. Countries: 1. Publications: 5.
Guatemala Internal Medicine Physicians' Knowledge of Non-communicable Disease Clinical Preventive Services
ClinicalTrials.gov study NCT01515111. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Precision Medicine for Prediction & Prevention of Early Pre-eclampsia
ClinicalTrials.gov study NCT04412681. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients
ClinicalTrials.gov study NCT00001937. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Changing Susceptible Body Constitution for COVID-19 Prevention by Chinese Medicine in Hong Kong Residents
ClinicalTrials.gov study NCT04668222. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Use of medicinal plants for COVID-19 prevention and respiratory symptom treatment during the pandemic in Cusco, Peru: A cross-sectional survey
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A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab
ClinicalTrials.gov study NCT06145373. IPD Sharing: YES. Countries: 2. Publications: 0.
A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia
ClinicalTrials.gov study NCT05662319. IPD Sharing: YES. Countries: 17. Publications: 0.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.