Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
17
datasets available to search
ShareScore release 0.9.0
Dataset results
17 results for “Panax notoginseng”
Feeding foliar nano-selenium biofortified Panax notoginseng could reduce the occurrence of glycolipid metabolism disorder in mice caused by high-fat diets
<p><span>Nano-selenium (nano-Se) has been extensively explored as a biostimulant for improving the quality of grain crops. However, there are few reports about the effect on the medicinal components of Chinese herbal medicine cultured with nano-Se. Here, we sprayed nano-Se during the cultivation of </span><span><em>Panax notoginseng</em> (SePN), and measured the changes of medicinal components compared with conventional <em>Panax notoginseng</em> (PN). Furthermore, we identified a more pronounced effect of SePN on reducing obesity in animals compared with PN. By measuring antioxidant capacity, histopathology, gene expression related to glycolipid metabolism, and gut microbiota composition, we propose a potential mechanism for SePN to improve animal health.</span><span> Compared with the control groups, foliar spraying of nano-Se increased saponins content (Rb2, Rb3, Rc, F2, Rb2, and Rf) in the roots of <em>Panax notoginseng</em>, and the content of Rb2 increased by 3.9 times in particular. Interestingly, animal studies indicated that taking selenium-rich <em>Panax notoginseng</em> (SePN) can further ameliorate liver antioxidation (SOD, MDA, and GSH) and enzyme activities involved in glycolipid metabolism (ATGL and PFK). It also relieved inflammation and regulated the expression of genes (<em>MCAD</em>, <em>PPAR-α</em>, and <em>PCSK9</em>) related to fatty acid oxidation.</span> <span>The abundance ratio of Firmicutes/Bacteroides and beneficial bacteria abundance (<em>Bifidobacterium</em>, <em>Butyricimonas</em>, and <em>Parasutterella</em>) in gut microbiota were improved relative to the control. In summary, the application of nano-Se on PN may</span> <span>effectively raise the content of <em>Panax notoginseng</em> saponins (PNS) and immensely lower the risk of metabolic disorders of glycolipids.</span></p>
Feeding foliar nano-selenium biofortified Panax notoginseng could reduce the occurrence of glycolipid metabolism disorder in mice caused by high-fat diets
Open the record for dataset details and reuse information.
Fig. 5 in Molecular differentiation of Panax notoginseng grown under different conditions by internal extractive electrospray ionization mass spectrometry and multivariate analysis
Fig. 5. Multivariate statistical analysis results of 9 different types of Panax notoginseng samples. (a) Score scatter plot of 2D PCA model, (b) Score scatter plot of 3D PCA model, (c) Score scatter plot of OPLS-DA model, (d) Bar plot with OPLS-DA model of VIP.
Fig. 4 in Molecular differentiation of Panax notoginseng grown under different conditions by internal extractive electrospray ionization mass spectrometry and multivariate analysis
Fig. 4. Tandem MS analysis of characteristic ions in Panax notoginseng samples. (a) MS3 spectrum of m/z 1143 → 1107→, (b) MS3 spectrum of m/z 1193 → 1149→, (c) MS3 spectrum of m/z 885 → 841, (d) MS3 spectrum of m/z 1031 → 987, (e) MS3 spectrum of m/z 1245 → 1209, (f) MS3 spectrum of m/z 968 → 931.
Fig. 3 in Molecular differentiation of Panax notoginseng grown under different conditions by internal extractive electrospray ionization mass spectrometry and multivariate analysis
Fig. 3. Mass spectra of different types of Panax notoginseng samples analyzed by iEESI-MS. (a) Mass spectrum of Panax notoginseng from Kunming, (b) Mass spectrum of Panax notoginseng from Qujing, (c) Mass spectrum of Panax notoginseng from Hongjiaozhou, (d) Mass spectrum of Panax notoginseng from Wenshan (1 year), (e) Mass spectrum of Panax notoginseng from Wenshan (2 year), (f) Mass spectrum of Panax notoginseng from Wenshan (3 year), (g) Mass spectrum of Panax notoginseng from Hongjiaozhou (black soil), (h) Mass spectrum of Panax notoginseng from Hongjiaozhou (white soil), (i) Mass spectrum of Panax notoginseng from Hongjiaozhou (red soil). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2 in Molecular differentiation of Panax notoginseng grown under different conditions by internal extractive electrospray ionization mass spectrometry and multivariate analysis
Fig. 2. Chemical structures of eight ginsenosides used in this study as reference standards. G, ginsenoside; NG, notoginsenoside; glc, glucoside; rha, rhamnoside; xyl, xyloside; ara, arabinoside.
Fig. 1 in Molecular differentiation of Panax notoginseng grown under different conditions by internal extractive electrospray ionization mass spectrometry and multivariate analysis
Fig. 1. Schematic illustration of iEESI-MS for direct analysis of Panax notoginseng samples. (a) Analytical procedure of Panax notoginseng analysis by iEESI-MS. Approximately 0.1 mg of Panax notoginseng tissue was loaded into the sample chamber by punching without sample pretreatment, (b) Disposable iEESI device and its components, (c) Photo of iEESI-MS interface.
Clinical Study on the Treatment of Hypertensive Intracerebral Hemorrhage With Panax Notoginseng Saponin
ClinicalTrials.gov study NCT02999048. IPD Sharing: Not stated. Countries: 0. Publications: 13.
Phased secondary small interfering RNAs in Panax notoginseng
GEO Series GSE98118. Panax notoginseng. 7 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Steamed Panax Notoginseng Alleviates CA-MRSA USA300-induced Necroptosis in Polymorphonuclear Neutrophils
GEO Series GSE284429. Staphylococcus aureus. 6 samples. Type: Expression profiling by high throughput sequencing.
Nitrate fertilizer alleviates ammonium toxicity by enhancing ACLA-3 in Panax notoginseng roots
GEO Series GSE112437. Panax notoginseng. 12 samples. Type: Expression profiling by high throughput sequencing.
The Effect of Panax Notoginseng Powders on Rheumatic Pain
ClinicalTrials.gov study NCT02260336. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Transcriptomics provides novel insights into the regulatory mechanism of Panax notoginseng exosome-like nanoparticles in HSF
GEO Series GSE203635. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Effect of Panax Notoginseng on gene expression in rats with cerebral ischemia-reperfusion injury
GEO Series GSE154098. Rattus norvegicus. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics provides novel insights into the regulatory mechanism of panax notoginseng derived exosome-like nanoparticles on HUVECs cells
GEO Series GSE203636. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA illumina sequencing of Panax notoginseng under CK and Cd stress treatment
GEO Series GSE108698. Panax notoginseng. 2 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics provides novel insights into the regulatory mechanism of Panax notoginseng exosome-like nanoparticles
GEO Series GSE203638. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.