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193 results for “Penicillium”
SH3-like domain from Penicillium virgatum muramidase: X-ray diffraction images
<p>This submission includes a zip archive of diffraction images recorded with the ADSC QUANTUM 315 CCD detector at the DIAMOND beamline I04 on 2017-06-27. The model of the crystal structure and associated information can be found in the Protein Data Bank entry 8B2G. This is a case of crystal twinning. The data are used in CCP4 Tutorials.</p>
Penicillium fuscoglaucum Pf_T2 Genome Assembly and Annotation
<p>During routine culturing on selective media in the lab, we obtained an isolate of P. fuscoglaucum Pf_T2 and sequenced its genome. The Pf_T2 genome is far superior to available genomic resources for the species. Our assembly exhibits a length of 35.1 Mb, a BUSCO score of 97.9% complete, and consists of 5 scaffolds/contigs representing the four expected chromosomes. It was determined that the Pf_T2 genome was colinear with a type specimen P. fuscoglaucum, and contained a lineage specific, intact cylcopaizonic acid (CPA) gene cluster.</p>
Figure 1 in Amazonian soil fungi are efficient degraders of glyphosate herbicide; novel isolates of Penicillium, Aspergillus, and Trichoderma
Figure 1. Mass spectrum resulting from the HPLC-MS of the isolated Penicillium 4A21 filtered. The filtrate presents possible peaks of glyphosate (170.07), AMPA (112.13) and sarcosine (89).
Figure 5 in Plant metabolite 5-pentadecyl resorcinol is produced by the Amazonian fungus Penicillium sclerotiorum LM 5679
Figure 5. Chemical structure of the isolated substance (5-pentadecyl resorcinol) by Penicillium sclerotiorum LM 5679.
Figure 4. HMBC 150 in Plant metabolite 5-pentadecyl resorcinol is produced by the Amazonian fungus Penicillium sclerotiorum LM 5679
Figure 4. HMBC 150 MHz (a) and HSQC 300 MHz (b) spectrum of the compound produced by Penicillium sclerotiorum LM 5679.
Figure 1 in Plant metabolite 5-pentadecyl resorcinol is produced by the Amazonian fungus Penicillium sclerotiorum LM 5679
Figure 1. Chromatographic fractionation of the compound produced by Penicillium sclerotiorum LM 5679.
Integrated Omics-Based Discovery of Novel Genes, Secondary Metabolites Clusters, and Small Molecules in Penicillium spp. with Disparate Fungal Isolates
<p><em><span>Penicillium expansum</span></em><span> is a ubiquitous postharvest pathogen of pome fruit that causes blue mold decay of apple fruit while another member of the genus, <em>P. chrysogenum</em><span>,</span><em> </em>is a well-studied saprophyte used for antibiotic and small molecule production. While these two fungi have been investigated individually, the recent discovery of <em>P. chrysogenum </em>hindering <em>P. expansum</em> apple fruit infection has not been well studied. To shed light on this interaction between the two species, we conducted a comparative transcriptomic, metabolomic, and genomic study. Global transcriptional and metabolomic outputs were disparate between the species, nearly identical for the <em>P. chrysogenum </em>isolates, and different between <em>P. expansum </em>isolates. Further, the two <em>P. chrysogenum</em> genomes revealed secondary metabolite gene clusters that differed from <em>P. expansum</em>. This included the absence of an intact patulin gene cluster in <em>P. chrysogenum</em>, which corroborates the metabolomic data regarding the species’ inability to produce patulin. Additionally, <em>P. expansum </em>virulence gene homologues were identified in <em>P. chrysogenum </em>and were similarly transcriptionally regulated <em>in vitro</em>. Molecules with potential antimicrobial activity, and phytohormones like indole-3-acetic acid (IAA), were detected for the first time in <em>P. expansum</em> while pharmacological compounds like the well-studied antibiotic penicillin G were identified in <em>P. chrysogenum</em> culture supernatants. Our findings provide new omics-based resources that enable the study of small molecule production of interest, the potential of <em>Penicillium</em>-derived antimicrobials for postharvest decay control, and <em>P.</em> <em>expansum’s</em> metabolites roles in host-pathogen interactions. </span></p>
Figure 3. NMR 13C in Plant metabolite 5-pentadecyl resorcinol is produced by the Amazonian fungus Penicillium sclerotiorum LM 5679
Figure 3. NMR 13C (75 MHz) spectrum of the compound produced by Penicillium sclerotiorum LM 5679.
Discovery of indole alkaloids crienamides A and B from penicillium citrinum by a simulated MS/MS-guided molecular network strategy
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Proteome of Penicillium funiculosum NCIM1228 and ∆Snf1 grown in glucose and Avicel in the presence as well as the absence of calcium
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Independent domestication events in the blue-cheese fungus Penicillium roqueforti
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supplemental materials for "Feruloyl Glyceride as a Natural Antimicrobial for Inhibiting Postharvest Penicillium Rot in Tomatoes by Accelerating the Deposit of Suberin"
<p>Supplemental Figures <br>Table S1. The sequence of qPCR primers<br>Table S2. Quantities of various compounds<br>Table S3. Differential metabolites with up-regulated expression<br>Table S4. Differentially expressed genes with up-regulated expression<br>Table S5. Differentially expressed genes in the suberin synthesis pathway<br>Table S6. Differential metabolites in suberin synthesis pathway<br>Table S7. Correlation analysis</p>
Effect of nanoclay on spread of common staining fungal spores (Aspergillus niger and Penicillium spp.) on the surface of medium density fibreboards
<p>Studies on the effect of nanoclay, impregnated into MDFs, on the mycological activity were conducted. The study attempted to optimise the nanoclay loading and processing parameters to ensure effective retardation of mycological attack from staining fungi <em>Penicillium spp.</em> and <em>Aspergillus niger</em>.</p>
Fungal Planet 2023 June - Penicillium nudgee
<p>Alignment and tree for Penicillium nudgee.</p>
Fig. 8 in Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR
Fig. 8. (A) The 3D structure and hydrogen bond interaction of compound 18 with FXR at the 50th ns MD stimulation. (B) The agonistic activity of compound 18 against the wild-type, mutant R341V, or S342V FXR. Data were shown as the mean ± SD, n = 4 (*p <0.05, **p <0.01, ***p <0.001 compared to the Ctrl group; #p <0.05, ##p <0.01, ###p <0.001 compared to the WT group).
Fig. 7 in Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR
Fig. 7. The RMSD (A) and RMSF (B) of compound 18 with FXR in 50 ns MD stimulation. (C) The volume of pock for a complex of compound 18 and FXR in 50 ns MD stimulation. (D–F) The energy of the complex (D), energy of contribution (E), and hydrogen bond number (F) of compound 18 with FXR in the 50 ns MD stimulation. (G) The distance of compound 18 with amino acid residues Val325, Met328, and Phe329. (H) The distance of compound 18 with amino acid residues Ser332 and Tyr369.
Fig. 5 in Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR
Fig. 5. (A) Effects of compound 18 (2 μM) towards FXR, SHP1, and BSEP mRNA levels. (B) Effects of compound 18 (2 μM) towards FXR, SHP1, FGF, and BSEP expression levels. (C) Quantitative analysis of FXR, SHP1, FGF, and BSEP expression levels. Data were shown as the mean ± SD, n = 3 (*p <0.05, **p <0.01, ***p <0.001 compared to the Ctrl group). CDCA (80 μM) was used as the positive control.
Fig. 4 in Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR
Fig. 4. Experimental and calculated ECD spectra of 1 (A) and 5–7 (B–D) at the CAM-B3LYP/def-tzvp level.
Fig. 2 in Polyketides with antimicrobial activities from Penicillium canescens DJJ-1
Fig. 2. Two possible planar structures of 1 deduced on the basis of 1H–1H COSY and HMBC correlations.
Fig. 6 in Meroterpenoids from the fungus Penicillium sclerotiorum GZU-XW03-2 and their anti-inflammatory activity
Fig. 6. Effect of compound 4 on LPS-stimulated protein iNOS expression in RAW264.7 cells. Data are presented as means ± SD (n = 3). ###p <0.001 versus the control group. *p <0.05, **p <0.01 versus the LPS group.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.