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13 results for “Pneumococcus”
Data and code for: Pneumococcus co-colonization and the stress-gradient-hypothesis
<p>Pneumococcus serotype co-colonization, caused by the polymorphic bacteria <em>Streptococcus pneumoniae</em>, has been increasingly investigated and reported in recent years. Yet, there is limited information on how co-colonization patterns vary globally, critical for understanding the evolution and transmission dynamics of these bacteria. Here we report on a rich dataset of cross-sectional pneumococcal colonization studies collected from the literature, where we quantified patterns of transmission intensity and co-colonization variation in children populations across different epidemiological settings. Fitting these data to an SIS model with co-colonization under the assumption of quasi-neutrality among multiple interacting strains, our analysis reveals strong patterns of negative co-variation between transmission intensity R<sub>0</sub> and susceptibility to co-colonization <em>k</em>, in support of the stress-gradient-hypothesis (SGH) in ecology. According to this hypothesis, ecological interactions between organisms shift positively as environmental stress increases. In our model higher environmental stress is represented via lower values of the basic reproduction number R<sub>0</sub>, and a shift towards positive interactions is represented via higher vulnerability to co-colonization (higher <em>k</em>) between pneumococcus serotypes.</p>
Data and code for: Pneumococcus co-colonization and the stress-gradient-hypothesis
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Data from: Unraveling the seasonal epidemiology of pneumococcus
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Prospective Trial of Vaccine Responses Against Pneumococcus and Influenza in Adult Cancer Patients 65 Years of Age and Older
ClinicalTrials.gov study NCT00741039. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pneumococcus rolls epigenetic dice with a six phase random switch that controls virulence
GEO Series GSE55182. Streptococcus pneumoniae. 12 samples. Type: Expression profiling by high throughput sequencing.
Global transcriptional responses of pneumococcus to human blood components and cerebrospinal fluid
GEO Series GSE214359. Streptococcus pneumoniae. 30 samples. Type: Expression profiling by high throughput sequencing.
1918 pandemic influenza virus and pneumococcus co-infection results in activation of coagulation and widespread pulmonary microvascular thrombosis in mice and humans
GEO Series GSE70445. Mus musculus. 34 samples. Type: Expression profiling by array.
Protecting From Pneumococcus in Early Life (The PROPEL Trial)
ClinicalTrials.gov study NCT02628886. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Immunological Memory Against Pneumococcus Induced by 3 Infant PCV 13 Vaccination Schedules
ClinicalTrials.gov study NCT03405805. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Differentially expressed genes in pneumococcus-infected THP-1 monocytes
GEO Series GSE161269. Homo sapiens. 6 samples. Type: Other.
Expression data from uninfected and pneumococcus-infected wt and PGLYPR4-KO primary alveolar epithelial cells
GEO Series GSE108358. Mus musculus. 4 samples. Type: Expression profiling by array.
CGH characterisation of non-typeable Streptococcus pneumococcus circulating in Portugal
GEO Series GSE58329. Streptococcus pneumoniae. 34 samples. Type: Genome variation profiling by array.
Expression data from uninfected and pneumococcus-infected wt and PGLYPR4-KO primary alveolar macrophages
GEO Series GSE126065. Mus musculus. 11 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.