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Dataset results
95 results for “Point-of-care testing”
Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Prevention
ClinicalTrials.gov study NCT05413551. IPD Sharing: YES. Countries: 1. Publications: 1.
Data from: Population-based screening for hepatitis C antibodies and active infection using a point-of-care test in a low prevalence area
<p><span><span><span><span><span><span><span><span><span><span><span><b>Background.</b> Data on the true prevalence of hepatitis C virus (HCV) infection in the </span></span></span></span></span></span></span></span></span></span></span><span><span><span><span><span><span><span><span><span><span><span>general population is essential to health policies. We evaluated a program implementing free universal HCV screening using a non-invasive point-of-care test (POCT) (OraQuick-HCV rapid test) in oral fluid in an urban area in Valencia, South-Eastern Spain. </span></span></span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span><span><span><b>Methods.</b> A cross-sectional study was performed during 2015-2017. Free HCV screening was offered by regular mail to 11,500 individuals aged 18 and over, randomly selected from all census residents in the Health Department. All responding participants filled in a questionnaire about HCV infection risk factors and were tested in their tertiary Hospital. In those with a positive POCT, results were confirmed by enzyme-immunoassay and HCV-RNA.</span></span></span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span><span><span><b>Results.</b> 1,206 persons agreed to participate (response rate: 11.16%). HCV antibodies were detected in 19 (1.60%) cases (age-sex standardized rate: 1.31%; 95%CI: 0.82-2.07), but only 8 showed positive HCV-RNA (age-sex standardized rate: 0.56%; 95%CI: 0.28-1.14). The majority (89%) of the cases were born before 1965 and 74% had at least one known risk factor for HCV infection. All anti-HCV positive individuals were already aware of their infection, and no undiagnosed cases were detected. The performance of the POCT was excellent for detecting active infection. </span></span></span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span><span><span><b>Conclusions.</b> These preliminary data suggest that HCV population screening with a POCT is feasible but, in our setting, mailing recruiting is not effective (11% response rate). The low prevalence of HCV antibodies and active infection in the participant population (with no new diagnoses made) suggests that, in our setting, underdiagnosis may be uncommon.</span></span></span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span><span><span><b>Files uploaded include the study database (Stata v.13) and the do.file of the study.</b></span></span></span></span></span></span></span></span></span></span></span></p>
Study to Verify Clinical Utility of Point-of-Care (POC) Thyroid Stimulating Hormone (TSH) Test Kits as Compared to Third Generation TSH Test Kit
ClinicalTrials.gov study NCT01921452. IPD Sharing: Not stated. Countries: 1. Publications: 1.
More Than a Machine: Make Point-of-care HIV-1 Viral Load Testing Effective in Rural Uganda
ClinicalTrials.gov study NCT04517825. IPD Sharing: YES. Countries: 1. Publications: 1.
Point-of-care Urine Monitoring of Adherence: Testing a Real-Time Urine Assay of Tenofovir in PrEP
ClinicalTrials.gov study NCT03935464. IPD Sharing: YES. Countries: 1. Publications: 6.
Point-of-Care Glucose Testing and Insulin Supplementation
ClinicalTrials.gov study NCT01702311. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Point-of-Care Testing (POCT) Detection and Management of Metabolic Syndrome in Patients With Mental Illness
ClinicalTrials.gov study NCT02029989. IPD Sharing: NO. Countries: 1. Publications: 2.
Urine Tenofovir Point-of-care Test to Identify Patients in Need of ART Adherence Support (UTRA Study)
ClinicalTrials.gov study NCT05333679. IPD Sharing: YES. Countries: 1. Publications: 57.
Task sharing for point-of-care testing: Review of national health policies and implementation landscape in 19 African countries
Open the record for dataset details and reuse information.
Data from: A population-based screening for hepatitis C antibodies and active infection using a point-of-care test in a low prevalence area
Open the record for dataset details and reuse information.
Data from: Sensitivity and specificity of point-of-care rapid combination syphilis-HIV-HCV tests
Background: New rapid point-of-care (POC) tests are being developed that would offer the opportunity to increase screening and treatment of several infections, including syphilis. This study evaluated three of these new rapid POC tests at a site in Southern California. Methods: Participants were recruited from a testing center in Long Beach, California. A whole blood specimen was used to evaluate the performance of the Dual Path Platform (DPP) Syphilis Screen & Confirm, DPP HIV-Syphilis, and DPP HIV-HCV-Syphilis rapid tests. The gold-standard comparisons were Treponema pallidum passive particle agglutination (TPPA), rapid plasma reagin (RPR), HCV enzyme immunoassay (EIA), and HIV-1/2 EIA. Results: A total of 948 whole blood specimens were analyzed in this study. The sensitivity of the HIV tests ranged from 95.7–100% and the specificity was 99.7–100%. The sensitivity and specificity of the HCV test were 91.8% and 99.3%, respectively. The treponemal-test sensitivity when compared to TPPA ranged from 44.0–52.7% and specificity was 98.7–99.6%. The non-treponemal test sensitivity and specificity when compared to RPR was 47.8% and 98.9%, respectively. The sensitivity of the Screen & Confirm test improved to 90.0% when cases who were both treponemal and nontreponemal positive were compared to TPPA+/RPR ≥1:8. Conclusions: The HIV and HCV on the multi-infection tests showed good performance, but the treponemal and nontreponemal tests had low sensitivity. These results could be due to a low prevalence of active syphilis in the sample population because the sensitivity improved when the gold standard was limited to those more likely to be active cases. Further evaluation of the new syphilis POC tests is required before implementation into testing programs.
Point-of-care Viral Load Testing to Enable Streamlined Care and Task Shifting for Chronic HIV Care
ClinicalTrials.gov study NCT03066128. IPD Sharing: YES. Countries: 1. Publications: 7.
Point-of-Care Testing of Coagulation in Patients Treated With Direct Oral Anticoagulants Extended
ClinicalTrials.gov study NCT04679298. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Urin-based Point-of-Care Testing for Direct Oral Anticoagulants in Stroke Patients
ClinicalTrials.gov study NCT06037200. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Study to Evaluate the Feasibility of Integrating the Point-of-care Testing for Sexually Transmitted Infections and HIV Into Community-based Clinics for MSM and TGW in Thailand
ClinicalTrials.gov study NCT03580512. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Point-of-care Viral Load Testing Among HIV-infected Adolescents in Haiti
ClinicalTrials.gov study NCT03288246. IPD Sharing: YES. Countries: 1. Publications: 2.
Direct-to-angio Approach From loCal hOspitals Based on a PoInt-of-care bLOod Test for LVO
ClinicalTrials.gov study NCT06910163. IPD Sharing: NO. Countries: 1. Publications: 11.
Point-of-care Tests for Vaginal Discharge in Nepal
ClinicalTrials.gov study NCT05977491. IPD Sharing: YES. Countries: 1. Publications: 1.
Point-of-care Testing of Respiratory Pathogens at Pediatric Emergency Room
ClinicalTrials.gov study NCT03932942. IPD Sharing: YES. Countries: 1. Publications: 1.
Point-of-Care Testing in Coagulopathic Patients Undergoing Cardiac Surgery - a Multicenter Study
ClinicalTrials.gov study NCT01826123. IPD Sharing: Not stated. Countries: 2. Publications: 2.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.