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ShareScore release 0.9.0
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13 results for “Polychlorinated biphenyl”
Data from: Developmental polychlorinated biphenyl (PCB) exposure impacts on voiding physiology persist into adulthood and influence sensitivity to bladder stimuli in mice
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A global, cross-system meta-analysis of polychlorinated biphenyl biomagnification
<p><span><span><span><span><span><span><span><span><span><span><span>Studies evaluating the mechanisms underpinning the biomagnification of polychlorinated biphenyls (PCBs), a globally prevalent group of regulated persistent organic pollutants, commonly couple chemical and stable isotope analyses to identify bioaccumulation pathways. <span><span>Due to </span></span>analytical costs constraining the taxonomic and geographic scope, sample size, and the range of compounds analyzed for most studies, and <span><span>study-to-study variation in methodologies and analytical resolution, </span></span>how PCBs biomagnify at food web, regional, and global scales remains uncertain. To overcome these constraints, we compiled diet (stable isotopes) and lipid-normalized PCB data from peer-reviewed studies reporting both values and used complementary analyses to evaluate the relative importance of global key PCB drivers and assess ecosystem- and ocean-wide biomagnification trends of sum total PCB concentrations (PCB<sub>ST</sub>), and the concentrations of seven individual PCB congeners, and their sum (PCB<sub>å7</sub>). We discovered that the number of congeners analyzed, region, and class were the most important factors predicting PCB<sub>ST</sub>, while, similarly, region, class and feeding location were the best predictors of PCB<sub>å7</sub> and all seven congeners. In addition, biomagnification analyses revealed that PCB<sub>ST</sub>, PCB<sub>Σ7</sub> and the seven individual PCBs all demonstrate a higher propensity for biomagnification in marine relative to freshwater food webs and within the Atlantic Ocean relative to the Pacific. We further found that some congeners exhibiting relatively high trophic magnification factors (TMFs) in the Atlantic exhibited low TMFs in the Pacific (such as PCB 118), while the order of individual congener TMFs relative to one another remained consistent across marine and freshwater ecosystems. Our analyses demonstrate that novel insights regarding PCB concentrations across taxonomic, food webs, regional and global scales can be gleaned by leveraging existing data to overcome analytical constraints. </span></span></span></span></span></span></span></span></span></span></span></p>
A global, cross-system meta-analysis of polychlorinated biphenyl biomagnification
Open the record for dataset details and reuse information.
Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes.
GEO Series GSE81541. Homo sapiens. 64 samples. Type: Methylation profiling by high throughput sequencing.
RNAseq of zebrafish (Danio rerio) developmentally exposed to the polychlorinated biphenyl 3,3'-dichlorobiphenyl (PCB-11)
GEO Series GSE118955. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
Interactions of Polychlorinated Biphenyls and Their Metabolites with the Brain and Liver Transcriptome of Female Mice
GEO Series GSE252621. Mus musculus. 62 samples. Type: Expression profiling by high throughput sequencing.
Identification of m6A-mediated changes in mouse liver after exposure to polychlorinated biphenyls (PCB126 and Aroclor1260) and high fat diet
GEO Series GSE202386. Mus musculus. 44 samples. Type: Other.
Transcriptional Response of Rhodococcus aetherivorans I24 to Polychlorinated Biphenyl-Contaminated Sediments.
GEO Series GSE17033. Rhodococcus aetherivorans. 30 samples. Type: Expression profiling by array.
Black Carbon Impacts on Paraburkholderia xenovorans Strain LB400 Cell Enrichment and Activity: Implications toward Lower-Chlorinated Polychlorinated Biphenyls Biodegradation
GEO Series GSE246487. Paraburkholderia xenovorans. 12 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic profiling changes of early adulthood with perinatal polychlorinated biphenyls and polychlorinated dibenzofurans exposure (Yucheng second generation) [methylation]
GEO Series GSE120228. Homo sapiens. 60 samples. Type: Methylation profiling by genome tiling array.
Transcriptomic responses of hornyhead turbot (Pleuronichthys verticalis) to environmentally relevant doses of polybrominated diphenyl ethers or polychlorinated biphenyls
GEO Series GSE151532. Pleuronichthys verticalis. 38 samples. Type: Expression profiling by array.
Effects of polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) on Arabidopsis thaliana.
GEO Series GSE99345. Arabidopsis thaliana. 9 samples. Type: Expression profiling by array.
Spatial transcriptomic profiling uncovers the molecular effects of the neurotoxicant polychlorinated biphenyls (PCBs) in the brains of adult mice
GEO Series GSE301012. Mus musculus. 4 samples. Type: Other.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.