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241 results for “Polyphenols”
Data From: Exploring Gelatin-A and Mouse Proline-Rich Protein 5 as Probes for Wine Polyphenols analysis by Quartz Crystal Microbalance with Dissipation Monitoring
<p>Polyphenols are essential in winemaking, affecting the wine's quality, color, astringency, bitterness, and chemical stability. Conventional methods for assessing polyphenolic content are both expensive and time-intensive, underscoring the need for new, efficient techniques.</p> <p>The Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) sensor is recognized for its speed and reliability as a label-free detection tool. This study applies QCM-D to evaluate Gelatin Type A (Gel-A) from porcine skin and Mouse Proline-Rich Protein 5 (MP5) for polyphenol analysis in red wines without pre-treatment. MP5 notably exhibited a linear dissipation signal response with both total polyphenol and hydroxybenzoic acid concentrations. These findings highlight the potential for creating a stand-alone sensor platform for real-time polyphenol monitoring in winemaking.</p>
Comparison of polyphenol degrading enzyme activities between forest types and soil horizons from 2003 to 2004
In the southern Appalachians Rhododendron maximum thickets suppress conifer and hardwood regeneration. While there has been research on the effects of R. maximum on physical and chemical environment, the functioning of R. maximum ericoid mycorrhizas has been unexplored. The litter of ericaceous plants tends to be rich in phenolic compounds. These compounds can form recalcitrant complexes with various forms of organic N, and may be responsible for lowering decomposition and N mineralization rates. While polyphenol-organic N complexes are highly recalcitrant, some fungi, particularly ericoid mycorrhizal fungi, have the ability to access this sequestered N. Since the litter of ericaceous plants is rich in phenolic compounds and ericoid mycorrhizal fungi are equipped to degrade phenolic compounds, polyphenol-organic N complexing may represent an N cycling strategy that prevents non-ericaceous plants from accessing sources of organic N. We propose to examine the activities of polyphenol degrading enzymes in the soil of R. maximum thickets and neighboring hardwood forests.
Calibration curves for Folin-Ciocalteu assay for reliable quantification of total polyphenols.
<p><span>Five different protocols (P1-P5) for determining total polyphenol content in samples were investigated and compared. Detailed information on the protocols are provided in: <br></span></p> <p><span>P1 </span><span>Singleton, V.L.; Rossi, J.A. Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents. <em>Am J Enol Vitic.</em> <strong>1965</strong>, <em>16</em>, 144–158, doi:10.5344/ajev.1965.16.3.144.</span></p> <p><span>P2<span> </span>Singleton, V.L.; Orthofer, R.; Lamuela-Raventós, R.M. [14] Analysis of Total Phenols and Other Oxidation Substrates and Antioxidants by Means of Folin-Ciocalteu Reagent. In <em>Methods in Enzymology</em>; Oxidants and Antioxidants Part A; Academic Press, 1999; Vol. 299, pp. 152–178.</span></p> <p><span>P3<span> </span>Cicco, N.; Lanorte, M.T.; Paraggio, M.; Viggiano, M.; Lattanzio, V. A Reproducible, Rapid and Inexpensive Folin–Ciocalteu Micro-Method in Determining Phenolics of Plant Methanol Extracts. <em>Microchemical Journal</em> <strong>2009</strong>, <em>91</em>, 107–110, doi:10.1016/j.microc.2008.08.011.</span></p> <p><span>P4. Sotenko, M.; Coles, S.; Barker, G.; Song, L.; Jiang, Y.; Longhurst, P.; Romanova, T.; Shuvaeva, O.; Kirwan, K. Phytoremediation-Biorefinery Tandem for Effective Clean-up of Metal Contaminated Soil and Biomass Valorisation. <em>International Journal of Phytoremediation</em> <strong>2017</strong>, <em>19</em>, 965–975, doi:10.1080/15226514.2016.1267705.</span></p> <p><span>P5<span> </span>Tsibranska, I.; Tylkowski, B.; Kochanov, R.; Alipieva, K. Extraction of Biologically Active Compounds from <em>Sideritis</em> Ssp. L. <em>Food and Bioproducts Processing</em> <strong>2011</strong>, <em>89</em>, 273–280, doi:10.1016/j.fbp.2010.10.004.</span></p> <p> </p> <p><span><span>Total polyphenol content was determined spectrophotometrically using different variation of Folin–Ciocalteu’s method by means of UV-VIS UV-1800 Shimadzu spectrophotometer (Tokio, Japan). </span><span>The Folin-Ciocalteu reagent, a</span><span> mixture of phosphomolybdic and phosphotungstic acids reacts with phenolic compounds and is reduced, forming a blue chromophore detectable spectrophotometrically. Seven concentration levels of gallic acid standard were used to construct the calibration curves: L1 - 0.6 g/L, L2 - 0.4 g/L, L3 - 0.2 g/L, L4 - 0.1 g/L, L5 - 0.05 g/L, L6 - 0.025 g/L and L7 - 0.0125 g/L. A 1 g/L gallic acid stock solution was prepared in Milli-Q water. Each concentration level was measured in triplicate using all the investigated polyphenol determination methods. Once the calibration curves for each method were prepared, </span><span>two independent standard solutions were used for methods validation. The first one was gallic acid at a concentration of 0.2 g/L prepared in Milli-Q water. The second standard was a commercial polyphenol extract Vitaflavan at a concentration of 0.2 g/L which contains 80% of total polyphenols. Each standard solution was measured in triplicate using all the methods investigated. </span></span></p>
Polyphenols' Inflammation-mediated Deglucuronidation and Promiscuous-binding Behavior for Antiviral Assaying and Trialing
<p>Dataset based on EMSKE Phytochem's pre-existing library of more than 250 Pubchem compounds that supports the research work Polyphenols’ Inflammation-mediated Deglucuronidation and Promiscuous-binding Behavior for Antiviral Assaying and Trialing. It refers to Jasial et al. 2016's dataset uploaded to Zenodo, <br> <br> Jasial, S.; Hu, Y.; Bajorath, J. PubChem Compounds Tested in Primary and Confirmatory Assays, 2016<br> <br> located at https://doi.org/10.5281/zenodo.44593 , which itself supports their work Jasial et al 2017: <br> <br> Jasial, S.; Hu, Y.; Bajorath, J. Determining the Degree of Promiscuity of Extensively Assayed Compounds. PLOS ONE 2016, 11 (4), e0153873. https://doi.org/10.1371/journal.pone.0153873.</p>
Figure 1. Standard curve for gallic acid y in Effect of extraction solvent system on the antimicrobial, antioxidant and total polyphenol content of the bark of Pistacia chinensis
Figure 1. Standard curve for gallic acid y = absorbance, x = concentration of Gallic Acid, R2 = correlation coefficient.
Floral tea polyphenols can improve honey bee memory retention and olfactory sensitivity
<p>Animal-pollinated plants face a common problem, how their defensive anti-herbivore compounds may impair or alter pollinator behavior. Evolution has tailored multiple solutions, which largely involve pollinator tolerance or manipulation, to the benefit of the plant, not the removal of these compounds from pollen or nectar. The tea plant, <em>Camilla sinensis</em>, is famous for the caffeine and tea polyphenols (TP) that it produces in its leaves. However, these compounds are also produced in its nectar, which honey bees readily collect. We examined the effects of these compounds on bee foraging choices, learning, memory, and olfactory sensitivity. Foragers preferred a sucrose feeder with 100 µg or 10 µg TP/ml over a control feeder. Caffeine, but not TP, weakly increased honey bee learning. Both caffeine and TP significantly increased memory retention, even when tested 7 d after the last learning trial. In addition, TP generally elevated EAG responsiveness to alarm pheromone odors. These results demonstrate that not only caffeine, but other secondary plant compounds, can attract pollinators and influence their learning and memory.</p>
The effect of polyphenol compounds on Helicobacter pylori eradication: a systematic review with meta-analysis
<p>Objectives: Polyphenol compounds are classified as organic compounds with phenolic units exhibiting a variety of biological functions. This meta-analysis aims to assess the efficacy and safety of polyphenol compounds (curcumin, cranberry, garlic, licorice, and broccoli) in eradicating Helicobacter pylori.</p> <p>Design: Systematic review and meta-analysis.</p> <p>Data sources: These include PubMed, Embase, The Cochrane Library, Web of Science, Medline, Chinese National Knowledge Infrastructure database , Chinese Scientific Journal Database , and Wan Fang database from inception to January 2022.</p> <p>Study selection: All randomized controlled trials comparing polyphenol compounds with the placebo or used as an adjunct treatment are included in this meta-analysis.</p> <p>Data synthesis: The treatment effect for dichotomous outcomes were assessed using risk ratio, while for continuous outcomes, mean differences (MDs) both with 95% CIs, were used. Subgroup analyses were carried out for different treatment schemes and polyphenol compound species. </p> <p>Results: 12 trials were included in the meta-analysis. The total eradication rate of H.pylori in the polyphenol compounds group was higher than in the group without polyphenol compounds. Statistical significance was also observed (RR 1.19, 95% CI:1.03 to 1.38, P=0.02). The most frequent adverse effects of polyphenol compounds included diarrhea, headache, and vomiting. However, there were no differences regarding side effects between the two groups (RR 1.47, 95% CI: 0.83 to 2.58, P=0.18). In subgroup analyses, the H.pylori eradication rate regimens with polyphenols therapy was superior to that of regimens without polyphenols therapy in the polyphenols versus placebo subgroup (RR 4.23, 95% CI:1.38 to 12.95, P=0.01), polyphenols plus triple therapy versus triple therapy subgroup (RR 1.11, 95% CI: 1.01 to 1.22, P=0.03).</p> <p>Conclusion: Polyphenol compounds can improve H.pylori eradication rates. Polyphenol compounds plus standard triple therapy can significantly improve the eradication. However, no evidence of a higher incidence of side effects could be found.</p> <p>PROSPERO registration number: CRD42022307477</p>
Red Grape Polyphenol Oral Administration to Women Affected by Nickel-mediated Allergic Contact Dermatitis
ClinicalTrials.gov study NCT03902392. IPD Sharing: NO. Countries: 1. Publications: 3.
Randomized Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol, a Plant Polyphenol, for COVID-19
ClinicalTrials.gov study NCT04400890. IPD Sharing: YES. Countries: 1. Publications: 2.
Inflammation, Polyphenols, and Genetics
ClinicalTrials.gov study NCT01568827. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota
ClinicalTrials.gov study NCT04018066. IPD Sharing: NO. Countries: 1. Publications: 1.
Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans
ClinicalTrials.gov study NCT03194620. IPD Sharing: YES. Countries: 1. Publications: 7.
Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL
ClinicalTrials.gov study NCT02998918. IPD Sharing: NO. Countries: 1. Publications: 24.
Efficacy of Polyphenols From Milk and Dark Chocolate
ClinicalTrials.gov study NCT00513344. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Whole plant disease severity is associated with reduced polyphenolic concentrations in lesioned but not green tissue in eelgrass
Open the record for dataset details and reuse information.
The effect of polyphenol compounds on Helicobacter pylori eradication: a systematic review with meta-analysis
Open the record for dataset details and reuse information.
Red rice bran polyphenols suppress invasive properties of HepG2 cells, possibly through Wnt/β-catenin-mediated EMT reversal.
<p>Data collection in its raw form is performed in a specific sequence dictated by the manuscript.</p>
Economic analysis for the production of gelatine and hydrolyzed collagen from fish by-products and carotenoids, coffee oil and polyphenols from spent coffee grounds
<p>The most relevant economic data of the processes were considered in a cost-benefit analysis for the production of gelatine and hydrolyzed collagen from fish by-products and carotenoids, coffee oil and polyphenols from spent coffee grounds in the Pilot 1 of WaysTUP! project.</p>
Data from: Pattern of polyphenol intake and the long-term risk of dementia in older persons
Objective: To investigate the optimal combination of dietary polyphenols associated with the long-term risk of dementia in a large prospective French cohort of older persons, the Three-City (3C) Study. Methods: We included 1,329 non-demented older adults from the 3C Study with assessment of intake of 26 polyphenol subclasses and followed for 12 years for dementia. Using Partial Least Square for Cox models, we identified a pattern of polyphenol intake associated with dementia risk. Results: The pattern combined several flavonoids (dihydroflavonols, anthocyanins, isoflavonoids, flavanones), stilbenes (including resveratrol), lignans and other subclasses (hydroxybenzaldehydes, naphtoquinones, furanocoumarins). Compared with participants in the lower quintile of pattern score, those in the higher quintile had a 50% lower risk of dementia (95% CI 20%; 68%, p-trend <0.01) in multivariate models. Conclusions: In this French cohort, a polyphenol pattern provided by a diet containing specific plant products (nuts, citrus, berries, leafy vegetables, soy, cereals, olive oil) accompanied with red wine and tea was associated with lower dementia risk.
Grape Polyphenols may prevent high fat diet-induced dampening of the hypothalamic-pituitary-adrenal axis in male mice
<p>Supplementary Materials. </p>
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