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14
datasets available to search
ShareScore release 0.9.0
Dataset results
14 results for “Poor graft function;”
Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplantation
ClinicalTrials.gov study NCT06171906. IPD Sharing: NO. Countries: 1. Publications: 2.
Peripheral Blood Stem Cell Combined With Mesenchymal Stem Cells for Treatment of Poor Graft Function
ClinicalTrials.gov study NCT02083718. IPD Sharing: Not stated. Countries: 1. Publications: 2.
MSCs With or Without Peripheral Blood Stem Cell for Treatment of Poor Graft Function and Delayed Platelet Engraftment
ClinicalTrials.gov study NCT02240992. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Study of Efficacy and Safety of Eltrombopag in Patients With Poor Graft Function
ClinicalTrials.gov study NCT03718533. IPD Sharing: YES. Countries: 1. Publications: 0.
Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplant
ClinicalTrials.gov study NCT01763086. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Decitabine for Poor Graft Function Post Allo-HSCT
ClinicalTrials.gov study NCT05907499. IPD Sharing: NO. Countries: 0. Publications: 12.
CD34+ Selected Stem Cell for Poor Graft Function or Graft Failure
ClinicalTrials.gov study NCT06569082. IPD Sharing: YES. Countries: 1. Publications: 0.
T-cell Depleted Hematopoietic Stem Cell Boosts Without Conditioning for Poor Marrow Graft Function Following Allogeneic Hematopoietic Stem Cell Transplantation
ClinicalTrials.gov study NCT02350777. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Decitabine and Umbilical Cord Blood for Poor Graft Function Post Allo-HSCT
ClinicalTrials.gov study NCT05669079. IPD Sharing: NO. Countries: 0. Publications: 5.
Eltrombopag For Secondary Poor Graft Function Post Allogeneic Hematopoietic Stem Cell Transplantation
ClinicalTrials.gov study NCT03437603. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function
ClinicalTrials.gov study NCT00603330. IPD Sharing: Not stated. Countries: 2. Publications: 0.
The Safety and Efficacy of Umbilical Cord Blood Mononuclear Cells in Patients With Secondary Poor Graft Function After Hematopoietic Stem Cell Transplantation
ClinicalTrials.gov study NCT06792682. IPD Sharing: Not stated. Countries: 1. Publications: 0.
RevErsing Poor GrAft Function With eLtrombopag After allogeneIc Hematopoietic Cell trAnsplantation
ClinicalTrials.gov study NCT03948529. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dataset related to article "Donor-Specific Anti-HLA Antibodies in Haploidentical Stem Cell Transplantation with Post-Transplantation Cyclophosphamide: Risk of Graft Failure, Poor Graft Function, and Impact on Outcomes."
<p>The presence of donor-specific anti-HLA antibodies (DSA) is associated with a 10-fold increased risk of graft failure in haploidentical stem cell transplantation (haplo-SCT). Consensus guidelines from the European Society for Blood and Marrow Transplantation set a mean fluorescence intensity (MFI) >1000 as a cutoff for DSA positivity. In the absence of an alternative donor, it is recommended that patients undergo desensitization therapy, especially with high DSA levels (>5000 MFI). The aim of this study was to analyze the impact of DSA on risk of graft failure and poor graft function, as well as on major outcomes in a consecutive cohort of patients who were systematically screened for DSA before haplo-SCT. A total of 141 consecutive patients were candidates for unmanipulated haplo-SCT with post-transplantation cyclophosphamide (PT-Cy) at our center between January 2012 and January 2018, and 135 were analyzed for the presence of HLA antibodies. Of these 134 patients underwent haplo-SCT. HLA antibodies were detected in 40 patients, including 19 with DSA and 21 without DSA. Ten of the 19 patients with DSA underwent transplantation using that donor, whereas 2 underwent a desensitization program before transplantation. Only 2 patients experienced primary graft failure (1.4 %), both of whom were without DSA. Twenty patients developed a poor graft function (15%). The 3-year overall survival (OS), 3-year progression-free survival (PFS), and 1-year nonrelapse mortality (NRM) were analyzed according to the presence or absence of DSA. No statistically significant difference was found. No impact of the presence of DSA on the risk of developing graft failure and poor graft function was revealed. Major outcomes of transplantation were analyzed separately in patients with poor graft function and those with good graft function. The 3-year OS, 3-year PFS, and 1-year NRM in good graft function and poor graft function populations were 62% versus 20% (P < .0001), 53% versus 20% (P < .0001), and 12% versus 40% (P = .009), respectively. The presence of low-level DSA in the absence of desensitization did not correlate with the risk of developing graft failure and poor graft function. Patients who experienced poor graft function had worse outcomes than patients with good graft function.</p>
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.