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ShareScore release 0.9.0
Dataset results
19 results for “Poxvirus”
Genomic associations with poxvirus across divergent island populations in Berthelot's pipit
<p><span>Understanding the mechanisms and genes that enable animal populations to adapt to pathogens is important from an evolutionary, health and conservation perspective. Berthelot's pipit (<em>Anthus berthelotii</em>) experiences extensive and consistent spatial heterogeneity in </span><span>avian pox infection pressure across its range of island populations</span><span>, thus providing an excellent system with which to examine how pathogen-mediated selection drives spatial variation in immunogenetic diversity. Here we test for evidence of genetic variation associated with avian pox at both an individual and population-level. At the individual level, we find no evidence that variation in MHC class I and TLR4 (both known to be important in recognising viral infection) was associated with pox infection within two separate populations. However, using genotype-environment association (Bayenv) in conjunction with genome-wide (ddRAD-seq) data, we detected strong associations between population-level avian pox prevalence and allele frequencies of single nucleotide polymorphisms (SNPs) at a number of sites across the genome. These sites were located within genes </span><span>involved in cellular </span><span>stress signalling and immune responses, many of which have previously been associated with responses to viral infection in humans and other animals. Consequently, our analyses indicates that pathogen-mediated selection may play a role in shaping genomic variation among relatively recently colonised island bird populations and highlights the utility of genotype-environment associations for identifying candidate genes potentially involved in host-pathogen interactions.</span></p>
Genomic associations with poxvirus across divergent island populations in Berthelot’s pipit
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Sequencing data for "Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays"
<p>Illumina and Oxford Nanopore sequencing datasets (in FASTQ format) generated for the manuscript "Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays." Paired-end Illumina MiSeq data are uploaded as two separate files ("r1" and "r2") for each passaged population. BAM files, filtered to exclude reads that did not align to K3L, are provided for passaged populations analyzed in the manuscript.</p>
SYSB3036_poxvirus_genomes
<p>Protein predictions from poxviruses</p>
Transcriptomic analysis of a symbiotic poxvirus in parasitoid wasps and fly hosts
GEO Series GSE122240. Anastrepha suspensa; Diachasmimorpha longicaudata; Diachasmimorpha longicaudata entomopoxvirus. 12 samples. Type: Expression profiling by high throughput sequencing.
Differential induction of apoptosis, IFN signaling and phagocytosis in macrophages infected with a panel of attenuated and non-attenuated poxviruses
GEO Series GSE79159. Homo sapiens. 12 samples. Type: Expression profiling by array.
Distinct modes of non-canonical initiation regulate selective host versus viral mRNA translation during poxvirus-induced shutoff
GEO Series GSE278320. Homo sapiens. 38 samples. Type: Other.
Profiling whole-tissue metabolic reprogramming during cutaneous poxvirus infection and clearance
GEO Series GSE236603. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Human SAMD9 is a Poxvirus-Activatable Anticodon Nuclease Inhibiting Codon-Specific Protein Synthesis
GEO Series GSE229979. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX
GEO Series GSE214751. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
A divergent and complementary transcriptional response in poxvirus-infected and bystander inflammatory monocytes is partly dictated by interferon.
GEO Series GSE215747. Mus musculus. 39 samples. Type: Expression profiling by high throughput sequencing.
Host-responses to Poxvirus-infected macrophages
GEO Series GSE120616. Mus musculus. 24 samples. Type: Expression profiling by array.
FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins
GEO Series GSE185829. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
A divergent and complementary transcriptional response in poxvirus-infected and bystander inflammatory monocytes is partly dictated by interferon [iMO IFN ECTV]
GEO Series GSE215745. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
A divergent and complementary transcriptional response in poxvirus-infected and bystander inflammatory monocytes is partly dictated by interferon [iMO_Bcells_ECTV]
GEO Series GSE215746. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Poxvirus attack of anti-viral defense pathways unleashes an effector-triggered NF-κB response
GEO Series GSE287860. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome dynamics of mutualistic poxvirus infection of tropical fruit fly hosts
GEO Series GSE228918. Ceratitis capitata; Bactrocera dorsalis; Zeugodacus cucurbitae. 81 samples. Type: Expression profiling by high throughput sequencing.
Poxvirus attack of anti-viral defense pathways unleashes an effector-triggered NF-κB response [RNAseq_MYXV_screen]
GEO Series GSE288433. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
Poxvirus attack of anti-viral defense pathways unleashes an effector-triggered NF-κB response [RNAseq_2]
GEO Series GSE288000. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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