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55 results for “Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa”
Data from: Back to the future: evolving bacteriophages to increase their effectiveness against the pathogen Pseudomonas aeruginosa PAO1
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Response of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity
Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety health and performance of the crewmembers. As a ubiquitous environmental organism that is occasionally part of the human flora Pseudomonas aeruginosa could pose a health hazard for the immuno-compromised astronauts. In order to gain insights in the behavior of P. aeruginosa in spaceflight conditions two spaceflight-analogue culture systems i.e. the rotating wall vessel (RWV) and the random position machine (RPM) were used. Microarray analysis of P. aeruginosa PAO1 grown in the low shear modeled microgravity (LSMMG) environment of the RWV compared to the normal gravity control (NG) revealed a regulatory role for AlgU (RpoE). Specifically P. aeruginosa cultured in LSMMG exhibited increased alginate production and up-regulation of AlgU-controlled transcripts including those encoding stress-related proteins. This study also shows the involvement of Hfq in the LSMMG response consistent with its previously identified role in the Salmonella LSMMG- and spaceflight response. Furthermore cultivation in LSMMG increased heat and oxidative stress resistance and caused a decrease in the culture oxygen transfer rate. Interestingly the global transcriptional response of P. aeruginosa grown in the RPM was similar to that in NG. The possible role of differences in fluid mixing between the RWV and RPM is discussed with the overall collective data favoring the RWV as the optimal model to study the LSMMG-response of suspended cells. This study represents a first step towards the identification of specific virulence mechanisms of P. aeruginosa activated in response to spaceflight-analogue conditions and could direct future research regarding the risk assessment and prevention of Pseudomonas infections for the crew in flight and the general public.
RNA-Seq analysis of Pseudomonas aeruginosa PAO1 cells infected with PhiKZ phage
GEO Series GSE58494. Pseudomonas aeruginosa; Phikzvirus phiKZ. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic profiles of Pseudomonas aeruginosa PAO1 grown in the presence or absence of mucins or mucin-glycans
GEO Series GSE136097. Pseudomonas aeruginosa. 15 samples. Type: Expression profiling by high throughput sequencing.
Co-transcriptional association of Hfq and Crc with the Pseudomonas aeruginosa PAO1 genome
GEO Series GSE111037. Pseudomonas aeruginosa PAO1. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNA Seq of Pseudomonas aeruginosa PAO1 exposed to DAS and DAE
GEO Series GSE151292. Pseudomonas aeruginosa PAO1. 9 samples. Type: Expression profiling by high throughput sequencing.
Comparative RNA-seq analysis of the transcriptome of the Pseudomonas aeruginosa PAO1 wild-type strain with that of the ΔvreR mutant
GEO Series GSE122253. Pseudomonas aeruginosa. 2 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq. and DNA-seq. of Pseudomonas aeruginosa PAO1 derived membrane vesicles
GEO Series GSE63388. Pseudomonas aeruginosa PAO1. 3 samples. Type: Expression profiling by high throughput sequencing.
Expression analysis of Pseudomonas aeruginosa PAO1 fatty acid synthesase II (FASII) deletions complemented by excess or limited expression of FASII genes accD, fabG, and fabF1
GEO Series GSE66045. Pseudomonas aeruginosa PAO1. 12 samples. Type: Expression profiling by array.
RNA-seq after knockdown of PhiKZ genes in PhiKZ-infected Pseudomonas aeruginosa PAO1 cells
GEO Series GSE269911. Pseudomonas aeruginosa PAO1. 126 samples. Type: Expression profiling by high throughput sequencing.
Expression profile of Pseudomonas aeruginosa ΔgcsR PAO1 using RNA-Seq
GEO Series GSE76522. Pseudomonas aeruginosa. 4 samples. Type: Expression profiling by high throughput sequencing.
The repressor C protein, Pf4r, controls superinfection of Pseudomonas aeruginosa PAO1 by the Pf4 filamentous phage and regulates host gene expression
GEO Series GSE154459. Pseudomonas aeruginosa PAO1. 11 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide analysis of Differential Responses of Pseudomonas aeruginosa PAO1 and PA14 cells to Interfacial Stress
GEO Series GSE112911. Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa PA14. 12 samples. Type: Expression profiling by high throughput sequencing.
Phenotypic and integrated analysis of a comprehensive Pseudomonas aeruginosa PAO1 library of mutants lacking cyclic-di-GMP-related genes
GEO Series GSE203348. Pseudomonas aeruginosa. 6 samples. Type: Expression profiling by high throughput sequencing.
Next Generation Sequencing Facilitates Quantitative Analysis of control of Pseudomonas aeruginosa PAO1 and geraniol-treated P. aeruginosa PAO1 Transcriptomes
GEO Series GSE216316. Pseudomonas aeruginosa PAO1. 6 samples. Type: Expression profiling by high throughput sequencing.
Pseudomonas aeruginosa PAO1 virulent genes in the poplar rhizosphere
GEO Series GSE5887. Populus sp.; Populus; Pseudomonas aeruginosa. 4 samples. Type: Expression profiling by array.
Response of Pseudomonas aeruginosa strain PAO1 to 10 mM added calcium in planktonic culture
GEO Series GSE74444. Pseudomonas aeruginosa. 4 samples. Type: Expression profiling by array.
Next Generation Sequencing Facilitates Quantitative Analysis of control of Pseudomonas aeruginosa PAO1 and diallyl disulphide-treated P. aeruginosa PAO1 Transcriptomes
GEO Series GSE118801. Pseudomonas aeruginosa PAO1. 6 samples. Type: Expression profiling by high throughput sequencing.
Pseudomonas aeruginosa PAO1 response to sphingomyelin
GEO Series GSE83078. Pseudomonas aeruginosa. 6 samples. Type: Expression profiling by array.
Transcriptional and proteomic response of Pseudomonas aeruginosa PAO1 to spaceflight conditions involves Hfq regulation and reveals a role for oxygen
GEO Series GSE22684. Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1. 8 samples. Type: Expression profiling by array.
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Allen Brain Atlas
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The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
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