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136 results for “Quercetin”
Navigating the Complex Solid Form Landscape of the Quercetin Flavonoid Molecule
<p>Data related to the paper published in Crystal Growth & Design, with doi:https://doi.org/10.1021/acs.cgd.3c00584.</p> <p>Quercetin, a naturally occurring bioflavonoid substance widely used in the nutraceutical and food industries, exists in various solid forms that can have different physicochemical properties, thus impacting this compound’s performance in various applications. In this work, we will clarify the complex solid-form landscape of this molecule. Two elusive isostructural solvates of quercetin were obtained from ethanol and methanol. The obtained crystals were characterized experimentally, but the crystallographic structure could not be solved due to their high instability. Nevertheless, the desolvated structure resulting from a high-temperature treatment (or prolonged storage at ambient conditions) of both these two labile crystals was characterized and solved via powder X-ray diffraction and solid-state nuclear magnetic resonance (SSNMR). This anhydrous crystal structure was compared with another anhydrous quercetin form obtained in our previous work, indicating that, at least, two different anhydrous polymorphs of quercetin exist. Navigating the solid-form landscape of quercetin is essential to ensure accurate control of the functional properties of food, nutraceutical, or pharmaceutical products containing crystal forms of this substance.</p>
Quercetin enhances the anti-tumor effects of BET inhibitors Supplementary Figures
<p>Supplementary Figures to "Quercetin enhances the anti-tumor effects of BET inhibitors" manuscript</p>
Quercetin in Coronary Artery By-pass Surgery
ClinicalTrials.gov study NCT04907253. IPD Sharing: NO. Countries: 1. Publications: 3.
Quercetin PK/PD Study in Healthy Adults and Patients With Hypercoagulable States
ClinicalTrials.gov study NCT01722669. IPD Sharing: YES. Countries: 1. Publications: 1.
Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease
ClinicalTrials.gov study NCT05422885. IPD Sharing: YES. Countries: 1. Publications: 1.
Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD)
ClinicalTrials.gov study NCT01708278. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Quercetin metabolite 4-methylcatechol does not directly augment the activity of Kv7.4 or Kv7.5
Open the record for dataset details and reuse information.
Data from: Fungicide suppression of flight performance in the honey bee (Apis mellifera) and its amelioration by quercetin
As a managed agricultural pollinator, the western honey bee Apis mellifera frequently encounters agrochemicals as contaminants of nectar and pollen. One such contaminant, the fungicide boscalid, is applied at bloom in orchards for fungal floral pathogen control. As an inhibitor of complex II in the mitochondrial electron transport chain of fungi, boscalid can potentially interfere with high energy-demanding activities of bees, including flight. We designed an indoor flight treadmill to evaluate impacts of ingesting boscalid and/or quercetin, a ubiquitous phytochemical in bee food that also affects mitochondrial respiration. Boscalid reduced the wing-beat frequencies of foragers during flight but did not alter the duration of flight. At the colony level, boscalid ingestion may thereby affect overall health by reducing forager efficiency. Consumption of quercetin, by contrast, led to higher adenosine triphosphate levels in flight muscles and a higher wing-beat frequency. Consuming the two compounds together increased wing beat frequency, demonstrating a hitherto unrecognized mechanism by which dietary phytochemicals may act to ameliorate toxic effects of pesticides to promote honey bee health. In carrying out this work, we also introduce two methodological improvements for use in testing for pesticide effects on flight capacity—a "force-feeding" to standardize flight fuel supply and a novel indoor flight treadmill.
Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data
<p>Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data</p>
Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data
<p>Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data</p>
Dataset for study of inhibition or activation of yeast and human IRE1 dimers, by Quercetin and Quercitrine.
<p>Docked structures, MD trajectories, BPMD simulation files and video of RNase motion cycles in apo scIre1p dimer. </p>
Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes
ClinicalTrials.gov study NCT00065676. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Pharmacological Profile of Different Quercetin Formulations
ClinicalTrials.gov study NCT05611827. IPD Sharing: NO. Countries: 1. Publications: 1.
Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure (FLAVO)
ClinicalTrials.gov study NCT01691404. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Quercetin in Children With Fanconi Anemia; a Pilot Study
ClinicalTrials.gov study NCT01720147. IPD Sharing: NO. Countries: 1. Publications: 1.
Possible Pharmacological Effect of Quercetin in the Management of Hyperuricemia - Results From Real-life Clinical Studies
ClinicalTrials.gov study NCT06652035. IPD Sharing: NO. Countries: 1. Publications: 1.
Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19
ClinicalTrials.gov study NCT04578158. IPD Sharing: NO. Countries: 1. Publications: 3.
Quercetin Effect on Post-ceserean Pain
ClinicalTrials.gov study NCT06650891. IPD Sharing: NO. Countries: 1. Publications: 1.
Effects of Quercetin on Blood Sugar and Blood Vessel Function in Type 2 Diabetes.
ClinicalTrials.gov study NCT01839344. IPD Sharing: Not stated. Countries: 1. Publications: 20.
Efficacy of Collagen, Propolis Plus Quercetin (Proqutin®), Bacillus Coagulans, Hyaluronic Acid and Chondroitin Sulphate and D-Mannose to Avoid Symptoms and Prevents Recurrence in Women With Recurrent
ClinicalTrials.gov study NCT06659016. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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OpenNeuro
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