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565 results for “RAS”
RAS Dataset
<p>The current challenge in effectively treating atrial fibrillation (AF) stems from a limited understanding of the intricate structure of the human atria. The objective and quantitative interpretation of the right atrium (RA) in late gadolinium-enhanced magnetic resonance imaging (LGE-MRI) scans relies heavily on its precise segmentation. Leveraging the potential of artificial intelligence (AI) - based approaches for RA segmentation presents a promising solution. However, the successful implementation of AI in this context necessitates access to a substantial volume of annotated LGE-MRI images for model training. In this paper, we present a comprehensive 3D cardiac dataset comprising 154 high-resolution LGE-MRI scans, each meticulously annotated at the pixel level. The annotation process underwent rigorous standardization through crowdsourcing among a panel of medical experts, ensuring the accuracy and consistency of the annotations. Our dataset represents a significant contribution to the field, providing a valuable resource for advancing AI-based RA segmentation methods.</p>
Protein structure files for the paper "Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth" in Nature Cell Biology by Tang et al.
<p>This archive contains models of HRAS, KRAS, and NRAS homo- and heterodimers with various mutations discussed in the paper, "Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth" in Nature Cell Biology by Tang et al.<br> as well as crystallographic dimers of these proteins as identified by the ProtCAD database, http://dunbrack2.fccc.edu/ProtCAD/Results/PfamArchClusterInfo.aspx?GroupId=8 (cluster 5). Several of the models are shown in Supp. Figure 11b and the crystallographic dimers of RAS that provide evidence for the possible biological relevance of these models are shown in Supp. Figure 11a.</p> <p>The crystallographic dimers were identified by clustering all possible interfaces generated by symmetry operators in crystals of HRAS, KRAS, and NRAS as described in the paper: Xu, Q., Dunbrack, R.L. ProtCID: a data resource for structural information on protein interactions. <em>Nat Commun</em> <strong>11</strong>, 711 (2020). https://doi.org/10.1038/s41467-020-14301-4.</p> <p>The models were created by superposing monomers of HRAS, KRAS, or NRAS onto the alpha4-alpha5 dimer present in the crystal of PDB entry 3k8y. Mutations were made in PyMOL. The structures were relaxed with the FastRelax protocol and the Ref2015 scoring function in the program Rosetta, which uses the backbone-dependent rotamer library of Shapovalov and Dunbrack to repack side chains.</p> <p>The crystallographic dimers are contained in a zipped PyMOL session. The mmCIF format for all the structures is present in a zip file, Tang_et_al_crystallographic_and_modeled_RAS_dimer_ciffiles.zip. The PyMOL session and zip file contains 87 HRAS dimers, 14 KRAS dimers, and 1 NRAS dimer, all having the interface consisting of the alpha4 and alpha5 helices. The PyMOL session also contains the modeled structures. Only Mg ions and GTP/GNP/GDP ligands are shown. Others are present but hidden and may be displayed by PyMOL ("show sticks, het").</p> <p> </p>
A saturation-mutagenesis analysis of the interplay between stability and activation in Ras
<p>Dataset for the Hidalgo et al. eLife paper DOI: <a href="https://doi.org/10.7554/eLife.76595">https://doi.org/10.7554/eLife.76595</a></p>
Mechanism-Based Redesign of GAP to Activate Oncogenic Ras
<p>Additional material for Berta et al. <em>J. Am. Chem. Soc.</em> 2023, 145, 37, 20302–20310</p> <ul> <li>Paths: minimised structures corresponding to the the GTP hydrolysis mechanism.</li> <li>MD setup: equilibriated inputs for classical MD simulations for WT and mutant systems in CHARMM/NAMD format, set up for the charmm36m FF.</li> <li>NBO: outputs for Natrual Bonding Orbitals analysis carried out for TS and RS structures.</li> <li>GAP mutants: optimised TS and RS structures of the most promising designed GAP mutants.</li> </ul>
Recurrent aphthous stomatitis cycle (RAS).
<p>"Recurrent aphthous stomatitis cycle (RAS Cycle)" . Creator: Esteban Núñez, Chile.</p> <p>Cite: Núñez, Esteban. (2020, April 24). Recurrent aphtous stomatitis cycle. Zenodo. DOI: 10.5281/zenodo.3765796</p>
Рис. 1. Карта-схема литоральных Экспедиций Института биологии морЯ (Национального научного центра морской биологии им. А.В. Жирмунского ДВО РАН) и Дальневосточного государственого университета (Дальневосточного федерального университета) (по: Ivanova, Tsurpalo [2012], с дополнениЯми). Fig. 1. A schematic map of intertidal expeditions performed by the Institute of Marine Biology (A.V. Zhirmunsky National Scientific Centre of Marine Biology FEB RAS) and Far Eastern State University (Far Eastern Federal University) (after Ivanova, Tsurpalo [2012], with additions). in Bivalve mollusks of the intertidal zone of the Far Eastern seas of Russia
Рис. 1. Карта-схема литоральных Экспедиций Института биологии морЯ (Национального научного центра морской биологии им. А.В. Жирмунского ДВО РАН) и Дальневосточного государственого университета (Дальневосточного федерального университета) (по: Ivanova, Tsurpalo [2012], с дополнениЯми). Fig. 1. A schematic map of intertidal expeditions performed by the Institute of Marine Biology (A.V. Zhirmunsky National Scientific Centre of Marine Biology FEB RAS) and Far Eastern State University (Far Eastern Federal University) (after Ivanova, Tsurpalo [2012], with additions).
Рис. 2. Laternula elliptica: А – раковина вЗрослого моллюска иЗ морЯ Дейвиса, L=87 мм, вид сбоку; Б – вид с дорсальной стороны (по: Егорова [1982]); В – расположение пустых раковин Laternula elliptica в осыпаюЩемсЯ песчаном грунте на склоне подводного холма (по рисунку иЗ полевого дневника Б.И. Сиренко, ЗИН РАН); Г – наружные отверстиЯ вводного и выводного сифонов Laternula elliptica (King, 1832) на поверхности грунта. Fig. 2. Laternula elliptica: А – shell of adult mollusc from the Davis Sea, L=87 mm, lateral view; Б – dorsal view (after: Егорова [1982]); В – empty shells of Laternula elliptica in friable sand on a slope of underwater hill (after sketch in the field journal of Dr. B.I. Sirenko, Zool. Inst. RAS); Г – external openings of inhalant and exhalant siphons of Laternula elliptica on surface of bottom deposits. in Species of warm-water origin Laternula elliptica (King, 1832) (Mollusca: Bivalvia: Laternulidae), a widespread mollusk in recent Antarctica
Рис. 2. Laternula elliptica: А – раковина вЗрослого моллюска иЗ морЯ Дейвиса, L=87 мм, вид сбоку; Б – вид с дорсальной стороны (по: Егорова [1982]); В – расположение пустых раковин Laternula elliptica в осыпаюЩемсЯ песчаном грунте на склоне подводного холма (по рисунку иЗ полевого дневника Б.И. Сиренко, ЗИН РАН); Г – наружные отверстиЯ вводного и выводного сифонов Laternula elliptica (King, 1832) на поверхности грунта. Fig. 2. Laternula elliptica: А – shell of adult mollusc from the Davis Sea, L=87 mm, lateral view; Б – dorsal view (after: Егорова [1982]); В – empty shells of Laternula elliptica in friable sand on a slope of underwater hill (after sketch in the field journal of Dr. B.I. Sirenko, Zool. Inst. RAS); Г – external openings of inhalant and exhalant siphons of Laternula elliptica on surface of bottom deposits.
Рис. 1. 1 — берег искусственного воΑоема на окраине посеΛка Витязь; 2 — северный скΛон горы Туманная; 3 — Amphipyra tripartita Butler, 1878, северный скΛон горы Туманная; 4 — Amphipyra tripartita Butler, 1878, ♂, Japonia, Ashia, ex coll. Erschov, коΛΛекция ЗИН; 5 — Oligonyx vulnerata (Butler, 1878); 6 — Cryphia bryophasma (Boursin, 1951); 7 — Cryphia griseola (Nagano, 1918); 8 — Stenoloba assimilis (Warren, 1909); 9 — Hadena aberrans (Eversmann, 1856) Fig. 1. 1 — the shore of an artificial reservoir on the outskirts of the Vityaz village; 2 — the northern slope of mount Tumannaya; 3 — Amphipyra tripartita Butler, 1878, the northern slope of mount Tumannaya; 4 — Amphipyra tripartita Butler, 1878, ♂, Japonia, Ashia, ex coll. Erschov, collection of the Zoological Institute RAS; 5 — Oligonyx vulnerata (Butler, 1878); 6 — Cryphia bryophasma (Boursin, 1951), the outskirts of the Vityaz village; 7 — Cryphia griseola (Nagano, 1918); 8 — Stenoloba assimilis (Warren, 1909); 9 — Hadena aberrans (Eversmann, 1856) in Amphipyra tripartita Butler, 1878 - new species for the fauna of Russia and other Noctuidae (Insecta, Lepidoptera), found in Gamov peninsula in September 2022
Рис. 1. 1 — берег искусственного воΑоема на окраине посеΛка Витязь; 2 — северный скΛон горы Туманная; 3 — Amphipyra tripartita Butler, 1878, северный скΛон горы Туманная; 4 — Amphipyra tripartita Butler, 1878, ♂, Japonia, Ashia, ex coll. Erschov, коΛΛекция ЗИН; 5 — Oligonyx vulnerata (Butler, 1878); 6 — Cryphia bryophasma (Boursin, 1951); 7 — Cryphia griseola (Nagano, 1918); 8 — Stenoloba assimilis (Warren, 1909); 9 — Hadena aberrans (Eversmann, 1856) Fig. 1. 1 — the shore of an artificial reservoir on the outskirts of the Vityaz village; 2 — the northern slope of mount Tumannaya; 3 — Amphipyra tripartita Butler, 1878, the northern slope of mount Tumannaya; 4 — Amphipyra tripartita Butler, 1878, ♂, Japonia, Ashia, ex coll. Erschov, collection of the Zoological Institute RAS; 5 — Oligonyx vulnerata (Butler, 1878); 6 — Cryphia bryophasma (Boursin, 1951), the outskirts of the Vityaz village; 7 — Cryphia griseola (Nagano, 1918); 8 — Stenoloba assimilis (Warren, 1909); 9 — Hadena aberrans (Eversmann, 1856)
Text-fig. 10. Typical elements of the flora of Sjurkum. 1 – Myrica vyvenkensis AKHMETIEV, leaf, × 0.7; 2 – Rhododendron lancifolium AKHMETIEV, leaf, × 0.7; 3, 4 – cf. Vaccinium sp., leaves, × 0.8 and 1; 5 – Salix sp. (ex gr. S. glauca L.), leaf, × 0.7; 6 – Carpinus sp., involucre, × 1 (coll. Geol. Inst. RAS Moscow). in Mid-Latitude Palaeogene Floras Of Eurasia Bound To Volcanic Settings And Palaeoclimatic Events - Experience Obtained From The Far East Of Russia (Sikhote-Alin') And Central Europe (Bohemian Massif)
Text-fig. 10. Typical elements of the flora of Sjurkum. 1 – Myrica vyvenkensis AKHMETIEV, leaf, × 0.7; 2 – Rhododendron lancifolium AKHMETIEV, leaf, × 0.7; 3, 4 – cf. Vaccinium sp., leaves, × 0.8 and 1; 5 – Salix sp. (ex gr. S. glauca L.), leaf, × 0.7; 6 – Carpinus sp., involucre, × 1 (coll. Geol. Inst. RAS Moscow).
Text-fig. 13. Typical elements of the flora of Velikaya Kema (coll. Geol. Inst. RAS Moscow). 1 – Abies sp. 1, twig, × 0.7; 2 – Larix sp., seed cone, × 0.7; 3 – Calocedrus sp., twig, × 0.7; 4 – Picea sp., seed, × 0.8; 5 – Abies sp. 2, seed, × 0.7; 6 – Metasequoia occidentalis (NEWBERRY) CHANEY, leafy shoot, × 0.7; 7 – Ostrya sp., involucre, × 0.7; 8 – Carpinus sp. (ex gr. C. cordata BLUME), involucre, × 0.7; 9 – Carpinus sp. 2 (ex gr. C. tschonoskii MAXIMOVITCH), involucre, × 0.7; 10 – Ulmus sp., leaf, × 0.7; 11 – Acer miocaudatum HU et CHANEY, leaf, × 0.8; 12 – Engelhardia (Alfaropsis) koreanica OISHI, ×; 13 – Comptonia naumannii NATHORST, leaf, × 0.7; 14 – Craigia oregonensis (ARNOLD) KVAČEK, BŮžEK et MANCHESTER, capsule valve, × 0.6; 15 – Cercidiphyllum crenatum (UNGER) R. BROWN, leaf, × 0.7; 16 – Sassafras subtriloba (KONNO) TANAI, leaf, × 0.7; 17 – Dicotylophyllum sp., leaf, × 0.7; 18 – Quercus kodairae HUZIOKA, leaf, × 1; 19 – Carpinus subcordata NATHORST, leaf, × 0.7; 20 – Ailanthus sp., fruit, × 1; 21 – Diospyros miokeaki HU et CHANEY, leaf, × 0.5. in Mid-Latitude Palaeogene Floras Of Eurasia Bound To Volcanic Settings And Palaeoclimatic Events - Experience Obtained From The Far East Of Russia (Sikhote-Alin') And Central Europe (Bohemian Massif)
Text-fig. 13. Typical elements of the flora of Velikaya Kema (coll. Geol. Inst. RAS Moscow). 1 – Abies sp. 1, twig, × 0.7; 2 – Larix sp., seed cone, × 0.7; 3 – Calocedrus sp., twig, × 0.7; 4 – Picea sp., seed, × 0.8; 5 – Abies sp. 2, seed, × 0.7; 6 – Metasequoia occidentalis (NEWBERRY) CHANEY, leafy shoot, × 0.7; 7 – Ostrya sp., involucre, × 0.7; 8 – Carpinus sp. (ex gr. C. cordata BLUME), involucre, × 0.7; 9 – Carpinus sp. 2 (ex gr. C. tschonoskii MAXIMOVITCH), involucre, × 0.7; 10 – Ulmus sp., leaf, × 0.7; 11 – Acer miocaudatum HU et CHANEY, leaf, × 0.8; 12 – Engelhardia (Alfaropsis) koreanica OISHI, ×; 13 – Comptonia naumannii NATHORST, leaf, × 0.7; 14 – Craigia oregonensis (ARNOLD) KVAČEK, BŮžEK et MANCHESTER, capsule valve, × 0.6; 15 – Cercidiphyllum crenatum (UNGER) R. BROWN, leaf, × 0.7; 16 – Sassafras subtriloba (KONNO) TANAI, leaf, × 0.7; 17 – Dicotylophyllum sp., leaf, × 0.7; 18 – Quercus kodairae HUZIOKA, leaf, × 1; 19 – Carpinus subcordata NATHORST, leaf, × 0.7; 20 – Ailanthus sp., fruit, × 1; 21 – Diospyros miokeaki HU et CHANEY, leaf, × 0.5.
Linked collectors and determiners for: Vascular plants from European Russia in the CSBG SB RAS Digital herbarium.
Natural history specimen data linked to collectors and determiners held within, "Vascular plants from European Russia in the CSBG SB RAS Digital herbarium". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/85f9137e-8aec-4e0b-9ed6-0af4dbe491e8">https://bionomia.net/dataset/85f9137e-8aec-4e0b-9ed6-0af4dbe491e8</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/85f9137e-8aec-4e0b-9ed6-0af4dbe491e8">https://gbif.org/dataset/85f9137e-8aec-4e0b-9ed6-0af4dbe491e8</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Family Geraniaceae in CSBG SB RAS herbarium collections (NS, NSK).
Natural history specimen data linked to collectors and determiners held within, "Family Geraniaceae in CSBG SB RAS herbarium collections (NS, NSK)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/c65575cf-862f-448b-bef2-fc158fb2e225">https://bionomia.net/dataset/c65575cf-862f-448b-bef2-fc158fb2e225</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/c65575cf-862f-448b-bef2-fc158fb2e225">https://gbif.org/dataset/c65575cf-862f-448b-bef2-fc158fb2e225</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Family Primulaceae in Digital Herbaria of CSBG SB RAS (NS).
Natural history specimen data linked to collectors and determiners held within, "Family Primulaceae in Digital Herbaria of CSBG SB RAS (NS)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/f8b3dfc3-e0d9-4173-a63b-436aedce0469">https://bionomia.net/dataset/f8b3dfc3-e0d9-4173-a63b-436aedce0469</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/f8b3dfc3-e0d9-4173-a63b-436aedce0469">https://gbif.org/dataset/f8b3dfc3-e0d9-4173-a63b-436aedce0469</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Typotheca of the higher vascular plants stored in M.G. Popov Herbarium (NSK) at the Central Siberian botanical garden SB RAS.
Natural history specimen data linked to collectors and determiners held within, "Typotheca of the higher vascular plants stored in M.G. Popov Herbarium (NSK) at the Central Siberian botanical garden SB RAS". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/e7a2f416-fea5-41bb-8f17-5217fcaa74d7">https://bionomia.net/dataset/e7a2f416-fea5-41bb-8f17-5217fcaa74d7</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/e7a2f416-fea5-41bb-8f17-5217fcaa74d7">https://gbif.org/dataset/e7a2f416-fea5-41bb-8f17-5217fcaa74d7</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Genus Allium in CSBG SB RAS herbarium collections (NS,NSK).
Natural history specimen data linked to collectors and determiners held within, "Genus Allium in CSBG SB RAS herbarium collections (NS,NSK)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/dc383f1f-6456-40bd-9ef1-0780cdb0c66d">https://bionomia.net/dataset/dc383f1f-6456-40bd-9ef1-0780cdb0c66d</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/dc383f1f-6456-40bd-9ef1-0780cdb0c66d">https://gbif.org/dataset/dc383f1f-6456-40bd-9ef1-0780cdb0c66d</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Genus Rhododendron in Digital herbarium of CSBG SB RAS (NS, NSK).
Natural history specimen data linked to collectors and determiners held within, "Genus Rhododendron in Digital herbarium of CSBG SB RAS (NS, NSK)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/a85dfdfc-345c-4b02-ba1e-140ca992b662">https://bionomia.net/dataset/a85dfdfc-345c-4b02-ba1e-140ca992b662</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/a85dfdfc-345c-4b02-ba1e-140ca992b662">https://gbif.org/dataset/a85dfdfc-345c-4b02-ba1e-140ca992b662</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Family Primulaceae in Digital Herbaria of CSBG SB RAS (NSK).
Natural history specimen data linked to collectors and determiners held within, "Family Primulaceae in Digital Herbaria of CSBG SB RAS (NSK)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/769dbaf7-8238-43fa-9717-90973e41706d">https://bionomia.net/dataset/769dbaf7-8238-43fa-9717-90973e41706d</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/769dbaf7-8238-43fa-9717-90973e41706d">https://gbif.org/dataset/769dbaf7-8238-43fa-9717-90973e41706d</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Genus Galium L. at the CSBG SB RAS collections (NS, NSK).
Natural history specimen data linked to collectors and determiners held within, "Genus Galium L. at the CSBG SB RAS collections (NS, NSK)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/e17d2584-dbc9-4a47-8743-a4e3a379fb33">https://bionomia.net/dataset/e17d2584-dbc9-4a47-8743-a4e3a379fb33</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/e17d2584-dbc9-4a47-8743-a4e3a379fb33">https://gbif.org/dataset/e17d2584-dbc9-4a47-8743-a4e3a379fb33</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Genus Hedysarum in CSBG SB RAS Digital herbarium.
Natural history specimen data linked to collectors and determiners held within, "Genus Hedysarum in CSBG SB RAS Digital herbarium". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/415f72e6-190e-4e71-80de-d376f4ae084d">https://bionomia.net/dataset/415f72e6-190e-4e71-80de-d376f4ae084d</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/415f72e6-190e-4e71-80de-d376f4ae084d">https://gbif.org/dataset/415f72e6-190e-4e71-80de-d376f4ae084d</a>. Formatted as a Frictionless Data package.
Linked collectors and determiners for: Salix pseudopentandra (Flod.) Flod. in the Herbarium (LE) of the Komarov Botanical Institute RAS.
Natural history specimen data linked to collectors and determiners held within, "Salix pseudopentandra (Flod.) Flod. in the Herbarium (LE) of the Komarov Botanical Institute RAS". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/07246b3c-69f9-4ad9-b952-8b8eb20cc4df">https://bionomia.net/dataset/07246b3c-69f9-4ad9-b952-8b8eb20cc4df</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/07246b3c-69f9-4ad9-b952-8b8eb20cc4df">https://gbif.org/dataset/07246b3c-69f9-4ad9-b952-8b8eb20cc4df</a>. Formatted as a Frictionless Data package.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.