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83 results for “Radionuclides”
Impact of medical radionuclide discharges on people and the environment: scenario data used in the non-human biota impact assessment
<p>This dataset contains the input data for the D-DAT model: activity concentrations in water for the simulated Molse Nete scenario. It also contains the dynamic model-calculated activity concentrations in sediment and the non-human biota. These are the primary data upon which the dose calculations werte performed, and they can be used to reproduce these calculations. The related preprint article is also given in this repository: https://zenodo.org/records/10488393.</p> <p> </p> <p> </p> <p> </p>
Cosmogenic radionuclide and thermochronology data from the Tian Shan and northern Pamir
<p>The zip folder <em>Kudriavtseva_etal_TianShan_Repository</em> contains the following files and folders:</p> <p>The excel file <em>Kudriavtseva_SuppInfo-Tables_S1-S7 </em>provides seven data tables with cosmogenic <sup>10</sup>Be, low-temperature thermochronology, and geospatial data from the Tian Shan and northern Pamir. These data tables form part of the Supporting Information for the study <em>"Impact of Quaternary glaciations on denudation rates in north Pamir </em><strong>– </strong><em>T<em>ian Sh</em>an inferred from cosmogenic <sup>10</sup>Be and low-temperature thermochronology" </em>by Kudriavtseva et al.</p> <p>The folders <em>Be10-glacial-correction </em>and <em>Be10-no_correction </em>include input files for calculating <sup>10</sup>Be-derived denudation rates using the open-source program CAIRN v.1 (Mudd et al., 2016) and shapefiles of drainage basins from the Tian Shan and northern Pamir. These data include original 10Be data from this study, as well as published 10Be data from Grin et al. (2018) and Charreau et al. (2023).</p> <p>The folder <em>Thermochronology_Data </em>includes two excel files summarizing published AFT and AHe data from the Tian Shan, input data for calculating exhumation rates using <em>age2exhume</em> MATLAB code (van der Beek & Schildgen, 2023), and the resulting exhumation rates. Additionally, this folder contains two text files with the input AFT and AHe data; they can be directly imported into MATLAB.</p>
Dose point kernels for 2,174 radionuclides
<p>Dose point kernels for 2,174 radionuclides generated using MCNP v6.2. See accompanying article in Medical Physics for further details. </p>
Figure 4 in Microtus guentheri (Danford & Alston, 1880) (Rodentia: Cricetidae) as a biomonitor for radionuclides in Mersin Province of Turkey
Figure 4. Distributions of the radiation hazard index values by locality (values around the circle show the numbers of localities).
Figure 3. Relationship between activity concentrations for 40K in Microtus guentheri (Danford & Alston, 1880) (Rodentia: Cricetidae) as a biomonitor for radionuclides in Mersin Province of Turkey
Figure 3. Relationship between activity concentrations for 40K as a function of altitude (significant).
Radionuclide, organic matter, geochemical and colorimetric properties of potential source material and target sediment for conducing sediment fingerprinting approaches in the Dzoumogné reservoir, Mayotte Island, France
<p>The current dataset was compiled to study sediment fingerprintings practices, i.e tracer selection and contribution modelling. Colorimetric properties analysed with a portable diffuse reflectance spectrophotometer (Konica Minolta CM-700d) and geochemical contents obtained with an energy dispersive X-ray fluorescence spectrometer (ED-XRF Epsilon 4), organic matter and stable isotopes were analysed by EA-IRMS and radionuclides using coaxial N- and P- type HPGe detectors (Canberra/Ortec). These properties were analysed in potential source material that may supply sediment to the Dzoumogné reservoir, Mayotte island, France. Three potential soil source materials (n = 57) were considered: cropland (n = 29), forest (n = 13) and subsurface material originating from channel bank collapse, landslides, badlands (n = 16). A sediment core was collected in the Dzoumogné reservoir (Target) on the 8th October 2021 and 20 layers were sampled.</p><p>The current dataset comprises two Excel files including the metadata description and the data itself.</p>
Nuclear excitation functions for medical isotope production: targeted radionuclide therapy via nat Ir(d, x)193mPt
<p><sup>193m</sup>Pt is a medically valuable Auger-emitting radionuclide, believed to have therapeutic potential, particularly when labeled to the chemotherapeutic drug cisplatin. One challenge to broader explorations of its clinical potential is the need for production routes with high specific activity. As part of a larger campaign to address gaps in reaction data for emerging medical radionuclides, this work seeks to characterize the <sup>nat</sup>Ir(d,x) reactions as a potential production pathway for <sup>193m</sup>Pt. A stacked target irradiation, consisting of natural iridium, iron, nickel, and copper foils, was performed using a 33 MeV deuteron beam at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. This measurement, along with previous experimental data, suggests an energy window between 11 to 18 MeV to maximize the production and radiopurity of <sup>193m</sup>Pt. This experiment has yielded cross sections for 42 reaction channels of deuteron-induced reactions from threshold to 30 MeV, including the first experimental results of <sup>nat</sup>Ir(d,x)<sup>188m1+g,190m1+g</sup>Ir (cumulative), <sup>nat</sup>Ni(d,x)<sup>56,57,58m,58g</sup>Co (independent), <sup>nat</sup>Ni(d,x)<sup>53</sup>Fe (cumulative), and <sup>nat</sup>Fe(d,x)<sup>48 V, 51 Cr</sup>(cumulative). The results were compared with literature data, the TENDL-2019 database, and default theoretical calculations from the TALYS-1.9, CoH-3.5.3, EMPIRE-3.2.3, and ALICE-2017 reaction modeling codes. This work presents another example of the lack of predictive capabilities for this set of modern nuclear-reaction modeling codes, and highlights unsatisfactory modeling in the A ≈ 190 mass region, which proved particularly difficult to model using CoH-3.5.3. Finally, this measurement has revealed weaknesses with the current evaluation of the <sup>nat</sup>Cu(d,x)<sup>63</sup>Zn deuteron monitor reaction.</p>
Dataset for the paper: Computational framework for radionuclide migration assessment in clay rocks
<p>This dataset contains OpenGeoSys-6 simulations results and scripts in Jupyter-notebook format for reproducing and visualizing the results of the paper:</p> <p>Garibay-Rodriguez J, Chen C, Shao H, Bilke L, Kolditz O, Montoya V and Lu R (2022) Computational Framework for Radionuclide Migration Assessment in Clay Rocks. Front. Nucl. Eng. 1:919541. doi: 10.3389/fnuen.2022.919541</p> <p>Details about the usage of the scripts can be found in the OpenGeoSys-6 user guide: https://www.opengeosys.org/</p>
Results of fallout radionuclides in the Rincon del Bonete and Palmar sediment cores (Uruguay)
<p>This database presents the results of fallout radionuclides performed on cores collected in the Rincon del Bonete and Palmar reservoirs (Uruguay) the 2019/09/01. Link to the publication https://www.nature.com/articles/s41893-023-01074-z</p> <p>Gamma spectrometry measurements were obtained using coaxial N- and P- type HPGe detectors (Canberra/Ortec) available at the Laboratoire des Sciences du Climat et de l’Environnement (Gif-sur-Yvette, France) . All activities were decay-corrected to 2020/06/01</p> <p>Corresponding authors: anthony.foucher@lsce.ipsl.fr</p> <p> </p>
Figure 1 in Microtus guentheri (Danford & Alston, 1880) (Rodentia: Cricetidae) as a biomonitor for radionuclides in Mersin Province of Turkey
Figure 1. The localities of samples collected within Mersin Province.
Radionuclide, particle size and elemental geochemistry analysis results of the Poechos sediment core, northern Peru
<p>This database presents the particle size, elemental geochemistry and radionuclide analyses carried out on the 19CO3 core (IGSN number: 10.58052/IEFOU0009) collected in June 2019 in the Poechos reservoir (Peru). These results are part of the publication <em>" El Niño-Southern Oscillation (ENSO)-driven hypersedimentation in the Poechos Reservoir, northern Peru "</em> available via the following link: http://dx.doi.org/10.5194/egusphere-2022-1233</p> <p>Corresponding authors: anthony.foucher@lsce.ipsl.fr</p> <p>Particle size analysis was performed using a laser grain sizer Malvern Mastersizer 3000 allowing to measure the grain size distribution between 10 nm and 3.5 mm. Particle size was measured on the sandy layers identified along the core (n=19) Grain size parameters such as d10, d50, d90 and raw are present on the file: <em>Particle_size_POECHOS-reservoir_Foucher-et-al</em></p> <p>Sediment core sections were analyzed with an Avaatech X-Ray Fluorescence core scanner (XRF) available at the Laboratoire des Sciences du Climat et de l’Environnement (Gif-sur-Yvette, France) with a 0.5 cm resolution. These data are available on the file: <em>XRF_core_scanner_POECHOS-reservoir_Foucher-et-al</em></p> <p>Gamma spectrometry measurements were obtained using HPGe detectors (Canberra/Ortec) available at the Laboratoire des Sciences du Climat et de l’Environnement. Short-lived radionuclides (e.g., caesium-137 (137Cs) and excess of lead-210 (210Pbex)) were measured in 12 samples of dry sediment (≈10g) collected along the sedimentary sequence (approximatively every 40 cm). The data are available on the file: <em>Radionuclides_POECHOS-reservoir_Foucher-et-al</em></p>
Uncovering transport, deposition and impact of radionuclides released after the early spring 2020 wildfires in the Chernobyl Exclusion Zone
<p>In the beginning of April 2020, large fires that started in the Chernobyl Exclusion Zone (CEZ) established after the Chernobyl accident in 1986 caused media and public concerns about the health impact from the resuspended radioactivity. In this paper, the emissions of previously deposited radionuclides from these fires are assessed and their dispersion and impact on the population is examined relying on the most recent data on radioactive contamination and emission factors combined with satellite observations. About 341 GBq of <sup>137</sup>Cs, 51 GBq of <sup>90</sup>Sr, 2 GBq of <sup>238</sup>Pu, 33 MBq of <sup>239</sup>Pu, 66 MBq of <sup>240</sup>Pu and 504 MBq of <sup>241</sup>Am were released in 1<sup>st</sup>–22<sup>nd</sup> April 2020 or about 1,000,000,000 times lower than the original accident in 1986 and mostly distributed in Central and East Europe. The large size of biomass burning particles carrying radionuclides prevents long-range transport as confirmed by low concentrations reported in Europe. The highest cumulative effective doses (>15 μSv) were calculated for firefighters and the population living in the CEZ, while doses were much lower in Kiev (2–5 μSv) and negligible in Europe. All doses are radiologically insignificant and no health impact on the European population is expected from the April 2020 fires.</p>
Data from: Exposure to environmental radionuclides is associated with altered metabolic and immunity pathways in a wild rodent
Wildlife inhabiting environments contaminated by radionuclides face putative detrimental effects of exposure to ionizing radiation, with biomarkers such as an increase in DNA damage and/or oxidative stress commonly associated with radiation exposure. To examine the effects of exposure to radiation on gene expression in wildlife, we conducted a de novo RNA sequencing study of liver and spleen tissues from a rodent, the bank vole Myodes glareolus. Bank voles were collected from the Chernobyl Exclusion Zone (CEZ), where animals were exposed to elevated levels of radionuclides, and from uncontaminated areas near Kyiv, Ukraine. Counter to expectations, we did not observe a strong DNA damage response in animals exposed to radionuclides, although some signs of oxidative stress were identified. Rather, exposure to environmental radionuclides was associated with upregulation of genes involved in lipid metabolism and fatty acid oxidation in the livers – an apparent shift in energy metabolism. Moreover, using stable isotope analysis, we identified that fur from bank voles inhabiting the CEZ had enriched isotope values of nitrogen: such an increase is consistent with increased fatty acid metabolism, but also could arise from a difference in diet or habitat between the CEZ and elsewhere. In livers and spleens, voles inhabiting the CEZ were characterized by immunosuppression, such as impaired antigen processing, and activation of leukocytes involved in inflammatory responses. In conclusion, exposure to low dose environmental radiation impacts pathways associated with immunity and lipid metabolism, potentially as a stress-induced coping mechanism.
Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides
<p>Altered copy number of certain highly repetitive regions of the genome, such as satellite DNA within heterochromatin and ribosomal RNA loci (rDNA), is hypothesized to help safeguard the genome against damage derived from external stressors. We quantified copy number of the 18S rDNA and a pericentromeric satellite DNA (Msat-160) in bank voles (Myodes glareolus) inhabiting the Chernobyl Exclusion Zone (CEZ), an area that is contaminated by radionuclides and where organisms are exposed to elevated levels of ionizing radiation. We found a significant increase in 18S rDNA and Msat-160 content in the genomes of bank voles from contaminated locations within the CEZ compared with animals from uncontaminated locations. Moreover, 18S rDNA and Msat-160 copy number were positively correlated in the genomes of bank voles from uncontaminated, but not in the genomes of animals inhabiting contaminated areas. These results show the capacity for local-scale geographic variation in genome architecture and are consistent with the genomic safeguard hypothesis. Disruption of cellular processes related to genomic stability appears to be a hallmark effect in bank voles inhabiting areas contaminated by radionuclides. --</p>
Radionuclides and grain size components in core QD2, South China Sea
<p>This file reports the radionuclide and grain size data for core QD2 (a core collected from coastal area of the South China Sea).</p>
Bone Marrow Suppression and Recovery During Radionuclide Treatment
ClinicalTrials.gov study NCT03247010. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Evaluation of Whole-body CZT Camera in Gated Tomographic Radionuclide Angiography
ClinicalTrials.gov study NCT04629937. IPD Sharing: NO. Countries: 1. Publications: 6.
In Men With Metastatic Prostate Cancer, What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy
ClinicalTrials.gov study NCT04343885. IPD Sharing: NO. Countries: 1. Publications: 1.
Capecitabine ON Temozolomide Radionuclide Therapy Octreotate Lutetium-177 NeuroEndocrine Tumours Study
ClinicalTrials.gov study NCT02358356. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Peptide Receptor Radionuclide Therapy (PRRT) in Tumors With High Expression of Somatostatin Receptors (Phase 2)
ClinicalTrials.gov study NCT04790708. IPD Sharing: YES. Countries: 1. Publications: 91.
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