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15 results for “Redox state”
Chloroplast redox state changes indicate cell-to-cell signalling during the hypersensitive response
<p>We performed detailed spatiotemporal analysis of chloroplast redox response to potato virus Y (PVY) infection in resistant <em>Ny</em><em>‐</em><em>1</em>-gene-bearing potato and its transgenic counterpart with impaired SA accumulation and compromised resistance. We found that the chloroplasts are highly oxidized in the cells adjacent to the cell death zone at different stages after virus inoculation in both genotypes. This hypothesis is further supported by highly induced formation of stroma filled tubules that extend from chloroplasts (stromules) in the cells adjacent to signalling cells. This dataset s a deposit of all the raw microscopy images of the study, plus the relevant metadata in ISA-tab compliant folder structure. </p> <p>After receiving reviews, we have made an additional experiment using a ROS inhibitor. The raw and processed data for this is in a separate file: _S_chlROS_inhibitor.zip</p> <p><br> <br> </p> <p><strong>Additional information about the microscopy images in this data deposit </strong></p> <ol> <li>Images of which name ends with <strong>ch00/ch01/ch02</strong> are maximum projections from Z-stacks for each ROI for each of three channels: chlorophyll fluorescence (ch00), GFP fluorescence after excitation with 405 nm laser line (ch01) and GFP fluorescence after excitation with 488 laser line (ch02), exported from Leica LAS X software.</li> <li>Only mesophyll cells are included in z-stack, except for the experiments with GFP-tagged PVY where additional z-stacks including both mesophyll and epidermal cells were produced ( »_2« added in the image name, see images with the comment »epidermal cells included in z-stack« in S_PhenodataRedox).</li> <li>Images of which name ends with <strong>ch00.tif</strong> and <strong>ch00.tif_ratio</strong> are analysed images, obtained using in-house Matlab script. These images were obtained by the analysis of ch00/ch01/ch02 images with the following steps: conversion to grayscale, filtering out pixels of low intensity, conversion to binary format using spatial adaptive thresholding, a round or erosion and dilation to remove single pixel noise around the chloroplasts, followed by size-based segmentation of individual chloroplasts. The ratios of fluorescence intensities 405/488 were then calculated for each pixel belonging to the chloroplast masks obtained in the previous step. Results were calculated per image (normalized to the fraction of pixels belonging to chloroplasts) and per individual chloroplast in each image.</li> <li>In the experiments with GFP-tagged PVY, due to high background signal in the cell death zone as a result of virus derived GFP fluorescence, signal in the 488 channel and 405/488 ratio (images named »scaled 488« and »405/488 in chloroplasts« in ch00.tif_ratio) in the cell death zone are not accurate.</li> <li>Figures of which name ends with <strong>ch00.tif_spatial_ROI1/ROI2</strong> show the 405/488 ratios in ROI1 or ROI2, determined for each pixel inside chloroplast masks for each Bin. See Image analysis in Methods for details.</li> <li>Experiment names and image names correspond to the names in S_PhenodataRedox. Details regarding experimental set-up and transgenic lines used are specified in S_PhenodataRedox.</li> </ol> <p>The Zenodo_reanalysis.zip file contains processed microscopic images in a new red/blue colormap. </p>
Data for article "Assembling diuranium complexes in different states of charge with a bridging redox-active ligand"
<p>This upload contains raw data (NMR, X-Ray, Elemental Analysis, AC & DC SQUID, EPR) files for the article.</p>
Data from: Redox state of NAD modulates the activation of Na-bicarbonate cotransporter NBCe1-B by IRBIT and L-IRBIT
<p>NAD is known as a coenzyme for many enzymes catalyzing redox reactions or as a substrate for enzymes for second messenger cADP-ribose generation or protein deacetylation. IRBIT and L-IRBIT are structurally conserved with dehydrogenases but lacking catalytic activity. By protein interaction, the IRBITs instead modulate many proteins of fundamental biological importance. Among these is the Na+-HCO3− cotransporter NBCe1-B, which plays a central role in intracellular pH (pHi) regulation and epithelial electrolyte transport. Here, we demonstrate that NAD modulates NBCe1-B activation by serving as a cofactor of the IRBITs. Blocking NAD salvage pathway decreases NBCe1-B activation by the IRBITs. NAD+ administration enhances, whereas NADH decreases NBCe1-B activity. Our study reveals a new role of NAD and greatly expands our appreciation of NAD biology. Because NAD redox state fluctuates greatly with metabolic status, our work provides insight into how, via IRBITs, energy metabolism could affect pHi regulation and many other IRBIT-dependent processes.</p>
Dataset of the article 'Redox state kinetics in water-oxidation IrOx electrocatalysts measured by operando spectroelectrochemistry'
<p>Data published in the article 'Redox state kinetics in water-oxidation IrO<sub>x</sub> electrocatalysts measured by <em>operando</em> spectroelectrochemistry', <a href="https://doi.org/10.1021/acscatal.1c03290">https://doi.org/10.1021/acscatal.1c03290</a>.</p> <p>Abstract: hydrous iridium oxides (IrO<sub>x</sub>) are the best oxygen evolution electrocatalysts available for operation in acidic environments. In this study, we employ time-resolved <em>operando</em> spectroelectrochemistry to investigate the redox states kinetics of IrO<sub>x</sub> electrocatalyst films for both water and hydrogen peroxide oxidation. Three different redox species involving Ir<sup>3+</sup>, Ir<sup>3.x+</sup>, Ir<sup>4+</sup> and Ir<sup>4.y+</sup> are identified spectroscopically and their concentrations are quantified as a function of applied potential. The generation of Ir<sup>4.y+</sup> states is found to be the potential determining step for catalytic water oxidation, whilst H<sub>2</sub>O<sub>2</sub> oxidation is observed to be driven by the generation of Ir<sup>4+</sup>states. The reaction kinetics for water oxidation, determined from the optical signal decays at open circuit, accelerate from ~ 20 s to < 0.5 s with increasing applied potential above 1.3V <em>vs.</em> RHE (i.e. TOFs per active Ir state increasing from 0.05 to 2 s<sup>-1</sup>). In contrast, the reaction kinetics for H<sub>2</sub>O<sub>2</sub> are found to be almost independent of the applied potential (increasing from 0.1-0.3 s<sup>-1 </sup>over a wider potential window), indicative of a first order reaction mechanism. These spectroelectrochemical data quantify the increase of both the density of active Ir<sup>4.y+</sup> states and the TOFs of these states with applied positive potential, resulting in the observed sharp turn on of catalytic water oxidation current. We reconcile these data with the broader literature while providing a unique kinetic insight into IrO<sub>x</sub> electrocatalytic reaction mechanisms, indicating a first order reaction mechanism for H<sub>2</sub>O<sub>2</sub> oxidation driven by Ir<sup>4+</sup> states, and a higher order reaction mechanism involving the co-operative interaction of multiple Ir<sup>4.y+</sup> states for water oxidation.</p>
Isolation and Redox Reactivity of Cerium Complexes in Four Redox States
<p>This upload contains raw data (NMR, X-Ray, UV, EPR, electrochemistry and Elemental Analysis) files for the article</p>
Data from: Redox state of NAD modulates the activation of Na-bicarbonate cotransporter NBCe1-B by IRBIT and L-IRBIT
Open the record for dataset details and reuse information.
Effect of the overexpression of the GGP1 gene on cell wall remodelling and redox state in the tomato fruit
<p> </p> <p>The deposited data were collected as a part of the studies entitled ‘Effect of the overexpression of the GGP1 gene on cell wall remodelling and redox state in the tomato fruit’.</p> <p>The research is the result of cooperation between institutions: </p> <ul> <li>Group for Plant Molecular Biology, Institute of Molecular Genetics and Genetic Engineering (IMGGE) at the University of Belgrade (Serbia),</li> <li>Institute of Agrophysics, Polish Academy of Sciences (Poland),</li> <li>Department of Pharmaceutical Sciences, at the Aristotle University of Thessaloniki (Greece).</li> </ul> <p>The use of advanced microscopic techniques (immunolabeling method), methods of molecular biology (Western blotting), and biochemistry (HPLC, measurement of enzyme activities) allows for expanding knowledge in the field of plant cell physiology and horticulture. </p> <p> The attached files have been compressed to *.zip format. The dataset consists of the following files:</p> <p>A_1_Antioxidant enzymes activities</p> <p>A_2_CLSM imaging</p> <p>A_3_Native polyacrylamide electrophoresis of antioxidant enzymes</p> <p>A_4_Phenolic components in the fruit tissue</p> <p>A_5_Western Blotting with quantitative analysis</p>
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's Disease
ClinicalTrials.gov study NCT03815916. IPD Sharing: NO. Countries: 1. Publications: 0.
Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes
GEO Series GSE229658. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing.
TMX2 is a key regulator of cellular redox state and its dysfunction causes severe brain developmental abnormalities
GEO Series GSE133483. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Redox State in the Course of Chronic Renal Insufficiency and Hemodialysis: Implications in Morbimortality
ClinicalTrials.gov study NCT00684034. IPD Sharing: Not stated. Countries: 1. Publications: 0.
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Amyotrophic Lateral Sclerosis (REPAIR-ALS)
ClinicalTrials.gov study NCT03843710. IPD Sharing: NO. Countries: 1. Publications: 0.
Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study
ClinicalTrials.gov study NCT03054961. IPD Sharing: NO. Countries: 1. Publications: 0.
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.
ClinicalTrials.gov study NCT03993171. IPD Sharing: NO. Countries: 1. Publications: 0.
Caliban regulates mitochondrial morphology and redox state in enterocytes to maintain intestinal homeostasis in Drosophila
GEO Series GSE125032. Drosophila melanogaster. 6 samples. Type: Expression profiling by array.
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