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Dataset results
29 results for “Reinnervation”
Labeled motor neurons following single and double nerve reinnervation of the long head of the biceps
<p>We developed a novel rat model to investigate the neurophysiological effects of peripheral double nerve transfers to a single target muscle. In 62 male Sprague-Dawley rats the ulnar nerve of the antebrachium alone (n=30) or together with the anterior interosseus nerve (n=32) was transferred to reinnervate the long head of the biceps brachii. To further assess reinnervation, retrograde labeling was performed. Twelve weeks following surgery retrograde tracer dyes were injected in the long head of the biceps muscle to stain the reinnervating motoneurons. In 7 control animals, the number of innervating motorneurons was assessed by injecting retrograde tracer in the untreated long head of the biceps.</p> <p>The aim of this dataset was to compare the effects of single nerve transfer and double nerve transfer on motor neuron count.</p>
Labeled motor neurons following single and double nerve reinnervation of the long head of the biceps
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Targeted Reinnervation as a Means to Treat Neuromas Associated With Major Limb Amputation
ClinicalTrials.gov study NCT02205385. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Targeted Muscle Reinnervation Study (TMR)
ClinicalTrials.gov study NCT05408520. IPD Sharing: NO. Countries: 1. Publications: 9.
Characterization of the Cardiac Reinnervation of Patients With Transposition of the Great Arteries Long After Repair With the Arterial Switch Operation. Correlation With Electrocardiographic and Exerc
ClinicalTrials.gov study NCT03469843. IPD Sharing: NO. Countries: 1. Publications: 4.
Targeted Sensory Reinnervation (TSR) in Hand Amputation
ClinicalTrials.gov study NCT06249594. IPD Sharing: NO. Countries: 2. Publications: 1.
Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction
ClinicalTrials.gov study NCT05997186. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Early Intracordal Hyaluronic Acid Injection During Spontaneous Reinnervation for Unilateral Recurrent Laryngeal Nerve Paralysis
ClinicalTrials.gov study NCT02163772. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Prevention of PostAmputation Pain With Targeted Muscle Reinnervation
ClinicalTrials.gov study NCT06719245. IPD Sharing: YES. Countries: 1. Publications: 26.
Reinnervation of Facial Muscles After Lengthening Temporalis Myoplasty
ClinicalTrials.gov study NCT01833221. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Data from: Electromyographic permutation entropy quantifies diaphragmatic denervation and reinnervation
Spontaneous reinnervation after diaphragmatic paralysis due to trauma, surgery, tumors and spinal cord injuries is frequently observed. A possible explanation could be collateral reinnervation, since the diaphragm is commonly double-innervated by the (accessory) phrenic nerve. Permutation entropy (PeEn), a complexity measure for time series, may reflect a functional state of neuromuscular transmission by quantifying the complexity of interactions across neural and muscular networks. In an established rat model, electromyographic signals of the diaphragm after phrenicotomy were analyzed using PeEn quantifying denervation and reinnervation. Thirty-three anesthetized rats were unilaterally phrenicotomized. After 1, 3, 9, 27 and 81 days, diaphragmatic electromyographic PeEn was analyzed in vivo from sternal, mid-costal and crural areas of both hemidiaphragms. After euthanasia of the animals, both hemidiaphragms were dissected for fiber type evaluation. The electromyographic incidence of an accessory phrenic nerve was 76%. At day 1 after phrenicotomy, PeEn (normalized values) was significantly diminished in the sternal (median: 0.69; interquartile range: 0.66–0.75) and mid-costal area (0.68; 0.66–0.72) compared to the non-denervated side (0.84; 0.78–0.90) at threshold p<0.05. In the crural area, innervated by the accessory phrenic nerve, PeEn remained unchanged (0.79; 0.72–0.86). During reinnervation over 81 days, PeEn normalized in the mid-costal area (0.84; 0.77–0.86), whereas it remained reduced in the sternal area (0.77; 0.70–0.81). Fiber type grouping, a histological sign for reinnervation, was found in the mid-costal area in 20% after 27 days and in 80% after 81 days. Collateral reinnervation can restore diaphragm activity after phrenicotomy. Electromyographic PeEn represents a new, distinctive assessment characterizing intramuscular function following denervation and reinnervation.
Cell Signaling, Reinnervation and Metabolism in Kennedy Disease and Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov study NCT05107349. IPD Sharing: YES. Countries: 1. Publications: 0.
Data from: Electromyographic permutation entropy quantifies diaphragmatic denervation and reinnervation
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Glial Guidance Drives Postnatal Intestinal Reinnervation by Enteric Neurons
GEO Series GSE242208. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Distal Electrical Stimulation Enhances Neuromuscular Reinnervation and Satellite Cell Differentiation for Functional Recovery
GEO Series GSE281936. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing.
Directed Functional Reinnervation to Curb Nociception and Enable Sensation
GEO Series GSE310748. Rattus norvegicus. 14 samples. Type: Expression profiling by high throughput sequencing.
Targeted Muscle Reinnervation in the Hand for the Managment of Symptomatic Neuroma Following Digit and Hand Amputations
ClinicalTrials.gov study NCT06923566. IPD Sharing: NO. Countries: 1. Publications: 0.
Targeted Reinnervation for Neuromas as a Means to Improve Prosthesis Control in Major Limb Amputation
ClinicalTrials.gov study NCT02316262. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Application of Targeted Reinnervation for People With Transradial Amputation
ClinicalTrials.gov study NCT02349035. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Bilateral Laryngeal Paralysis Reinnervation
ClinicalTrials.gov study NCT00213616. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.