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ShareScore release 0.9.0
Dataset results
14 results for “Riboswitch”
Riboswitch-inspired toehold riboregulators for gene regulation in Escherichia coli
<p>This dataset comprises flow cytometry data accompanying a publication on the development of synthetic riboregulators.</p> <p>These riboregulators were inspired by the architecture of naturally occurring riboswitches and toehold-mediated strand displacement. Specifically, we adopt the toehold switch hairpin and inserted regulatory sequences within the loop region of which accessibility can be controlled by toehold-mediated strand displacement. We utilized this design principle to develop toehold translation repressor and toehold transcriptional repressor, which regulate mCherry expression in <em>E. coli </em>in translational and transcriptional levels with certain ON/OFF ratios. Furthermore, we combined these two riboregulators and developed them into a NOR gate switch that can regulate downstream GFP expression in <em>E. coli </em>with different input conditions of trigger RNA. We used flow cytometry to quantify the expression level of the NOR gate switch under different inputs.</p>
Ha-SingleMoleculeLab's data for publication: Linking folding dynamics and function of SAM/SAH riboswitches at the single molecule level
<p>This upload is the raw data that support our findings sent to review on Nucleic Acids Research, corresponding to each individual figure. The paper title is " Linking folding dynamics and function of SAM/SAH riboswitches at the single molecule level".</p>
RNA Ensembles From Solvent Accessibility Data: Application to the SAM-I Riboswitch Aptamer Domain
<p>SASA-derived ensembles of the -SAM and +SAM states of the SAM-responsive riboswitch.</p>
TECdisplay data for Clostridium beijerinckii pfl ZTP riboswitch variant libraries
<p>Transcription termination/antitermination efficiency data for the <em>Clostridium beijerinckii</em> <em>pfl</em> ZTP riboswitch variant libraries. Data were generated using the Transcription Elongation Complex Display (TECdisplay) procedure.</p>
Linked multipoint cotranscriptional RNA chemical probing data for the E. coli SRP RNA, C. beijerinckii pfl ZTP riboswitch, and B. cereus crcB fluoride riboswitch
<p>Cotranscriptional RNA chemical probing data for the <em>E. coli</em> signal recognition particle (SRP) RNA, <em>Clostridium beijerinckii pfl</em> ZTP riboswitch, and <em>Bacillus cereus crcB </em>fluoride riboswitch. Data were generated using the linked multipoint Transcription Elongation Complex RNA structure probing (TECprobe-LM) and variable length Transcription Elongation Complex RNA structure probing (TECprobe-VL) procedures.</p>
Cotranscriptional RNA chemical probing data for ZTP, fluoride, and ppGpp riboswitches
<p>Cotranscriptional RNA chemical probing data for the <em>Clostridium beijerinckii pfl</em> ZTP riboswitch, <em>Bacillus cereus crcB </em>fluoride riboswitch, and <em>Clostridiales bacterium oral taxon </em>876<em> </em>str. F0540 ppGpp riboswitch. Data were generated using the Transcription Elongation Complex RNA structure probing-multilength (TECprobe-ML) and single length (TECprobe-SL) procedures.</p>
Single-molecule and bulk fluorescence and biolayer interferometry on the NAD-II riboswitch and its interactions with NMN
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Sequestration of a two-component response regulator by a riboswitch regulated non-coding RNA
GEO Series GSE60363. Listeria monocytogenes EGD-e. 8 samples. Type: Expression profiling by high throughput sequencing.
Functional Validation of SAM Riboswitch Element A from Listeria monocytogenes
GEO Series GSE266872. Listeria monocytogenes. 4 samples. Type: Other.
High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells
GEO Series GSE143466. Homo sapiens. 125 samples. Type: Other.
DANCE-MaP probing of the adenine riboswitch
GEO Series GSE182552. Vibrio vulnificus. 32 samples. Type: Other.
Specific targeting of transcriptional T-box riboswitches leads to effective inhibition of S. aureus
GEO Series GSE300037. Staphylococcus aureus. 4 samples. Type: Expression profiling by high throughput sequencing.
Cyclic diguanylate regulates virulence factor genes via multiple riboswitches in Clostridium difficile
GEO Series GSE120198. Clostridioides difficile. 8 samples. Type: Expression profiling by high throughput sequencing.
A dual T-box riboswitch in Enterococcus faecium binds two tRNAs
GEO Series GSE161499. Enterococcus faecium. 8 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.