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15
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ShareScore release 0.9.0
Dataset results
15 results for “SCN1A”
Design and cloning of a pair of split-GFP constructs to examine one of the split-sites for SCN1A
<p>Design and cloning of split-GFP constructs to investigate a potential split-sites for SCN1A fragments complementation.</p>
Checking the expression and localization of split-SCN1A constructs in HEK293 cells
<p>Examine the functionality (expression, ability to reconstitute, and localization of re-assembled SCN1A) of split-SCN1A-GFP1-10 and split-SCN1A-GFP11 constructs</p>
Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice
GEO Series GSE169481. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice II
GEO Series GSE169485. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Temporally controlled Scn1a gene reconstitution rescues seizures, behavioral deficits and altered gene expression after symptom onset in Dravet syndrome mice
GEO Series GSE171191. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq analysis of Scn1a +/- mouse
GEO Series GSE153461. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Longitudinal Study of Phenotypic and Developmental Severity in Patients With Dravet Syndrome With SCN1A Gene Mutation
ClinicalTrials.gov study NCT07251673. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome
ClinicalTrials.gov study NCT06283212. IPD Sharing: NO. Countries: 1. Publications: 0.
A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)
ClinicalTrials.gov study NCT06112275. IPD Sharing: NO. Countries: 1. Publications: 0.
SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom
ClinicalTrials.gov study NCT06504511. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
ClinicalTrials.gov study NCT05419492. IPD Sharing: NO. Countries: 1. Publications: 0.
dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and restrains epileptic crises in Dravet syndrome mice
GEO Series GSE111436. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Phenotypic variability in SCN1A-associated febrile seizures: transcriptomic and electrophysiological insights from iPSC-derived neurons
GEO Series GSE289689. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
SCN1A pathogenic variants do not have a distinctive blood-derived DNA methylation signature
GEO Series GSE280241. Homo sapiens. 45 samples. Type: Methylation profiling by array.
Drug screening for Dravet syndrome using Scn1a zebrafish mutants
GEO Series GSE43312. Danio rerio. 8 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.