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4 results for “SPR assay”
Testing Selectivity of USP5 Zf-UBD Analogues with SPR Assay
<p>A surface plasmon resonance (SPR) assay is used to determine binding affinities of commercial compound analogues against the zinc finger ubiquitin binding domain (Zf-UBD) of USP5 and test for selectivity against HDAC6 Zf-UBD </p>
Testing USP5 ZnF-UBD analogues with a Displacement Assay and SPR
<p>20 <a href="https://zenodo.org/record/3356885#.XcwPD1dKjIV">commercial analogues</a> from the Enamine REAL database were screened against the USP5 zinc finger ubiquitin-binding domain (ZnF-UBD) using a <a href="https://zenodo.org/record/3403804#.XcwPjFdKjIV">displacement assay</a> and the binding potency of best displacing compounds was assessed with a surface plasmon resonance (SPR) assay</p>
The raw data from FP and SPR assays for characterizing DCAF12 interactions with CCT5 and MAGEA3 peptides
<p>The source data underlying Figs 1A-E and Figs 2D-E for the DCAF12 manuscript (Title: Probing CRL4DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons)</p>
Testing Hit Analogues against USP5 Zf-UBD with SPR Assay #1
<p>A surface plasmon resonance (SPR) assay is used to determine binding affinities of <a href="https://zenodo.org/record/1490065#.XEnYI1xKjIV">commercial compound analogues previously selected</a> to explore the structure activity relationship (SAR) around our primary hits against the zinc finger ubiquitin binding domain (Zf-UBD) of USP5.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.