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37 results for “Scabies”
Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon
ClinicalTrials.gov study NCT04205669. IPD Sharing: YES. Countries: 1. Publications: 1.
Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands
ClinicalTrials.gov study NCT03236168. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Oral ivermectin versus 5% permethrin cream to treat children and adults with classic scabies: multicenter, assessor-blinded, cluster-randomised clinical trial
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Data from: Impact of an ivermectin mass drug administration on scabies prevalence in a remote Australian Aboriginal community
Background: Scabies is endemic in many Aboriginal and Torres Strait Islander communities, with 69% of infants infected in the first year of life. We report the outcomes against scabies of two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community. Methods: Utilizing a before and after study design, we measured scabies prevalence through population census with sequential MDAs at baseline and month 12. Surveys at months 6 and 18 determined disease acquisition and treatment failures. Scabies infestations were diagnosed clinically with additional laboratory investigations for crusted scabies. Non-pregnant participants weighing ≥15 kg were administered a single 200 μg/kg ivermectin dose, repeated after 2–3 weeks if scabies was diagnosed, others followed a standard alternative algorithm. Principal Findings: We saw >1000 participants at each population census. Scabies prevalence fell from 4% at baseline to 1% at month 6. Prevalence rose to 9% at month 12 amongst the baseline cohort in association with an identified exposure to a presumptive crusted scabies case with a higher prevalence of 14% amongst new entries to the cohort. At month 18, scabies prevalence fell to 2%. Scabies acquisitions six months after each MDA were 1% and 2% whilst treatment failures were 6% and 5% respectively. Conclusion: Scabies prevalence reduced in the six months after each MDA with a low risk of acquisition (1–2%). However, in a setting where living conditions are conducive to high scabies transmissibility, exposure to presumptive crusted scabies and population mobility, a sustained reduction in prevalence was not achieved. Clinical Trial Registration: Australian New Zealand Clinical Trial Register (ACTRN—12609000654257).
Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children and Adults
ClinicalTrials.gov study NCT02407782. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Veron Scabies Education and Eradication Program
ClinicalTrials.gov study NCT00604084. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Efficacy and Safety Study of Moxidectin in Adults With Scabies
ClinicalTrials.gov study NCT05875441. IPD Sharing: UNDECIDED. Countries: 4. Publications: 0.
Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies
ClinicalTrials.gov study NCT02841215. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Bioequivalence Study With Clinical Endpoints to Evaluate the Safety and Therapeutic Equivalence of Permethrin Cream 5% & Elimite™ in Subjects With Scabies
ClinicalTrials.gov study NCT03973775. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Sulfur vs. Different Regimes of Permethrin for Scabies
ClinicalTrials.gov study NCT06396507. IPD Sharing: NO. Countries: 1. Publications: 11.
Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study)
ClinicalTrials.gov study NCT05500326. IPD Sharing: YES. Countries: 1. Publications: 1.
Comparative Study Between Topical Permethrin 5% and Oral Ivermectin for the Treatment of Scabies
ClinicalTrials.gov study NCT05362513. IPD Sharing: NO. Countries: 1. Publications: 1.
Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji
ClinicalTrials.gov study NCT03177993. IPD Sharing: YES. Countries: 1. Publications: 2.
Risk Factors for Treatment Failure of Scabies in Autochthonous Populations of French Guiana (GUYAGALE)
ClinicalTrials.gov study NCT04931680. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Impact of an ivermectin mass drug administration on scabies prevalence in a remote Australian Aboriginal community
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Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies.
ClinicalTrials.gov study NCT02978508. IPD Sharing: NO. Countries: 1. Publications: 0.
Dose-finding Study of Moxidectin for Treatment of Scabies
ClinicalTrials.gov study NCT03905265. IPD Sharing: NO. Countries: 3. Publications: 0.
Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies
ClinicalTrials.gov study NCT02485717. IPD Sharing: NO. Countries: 1. Publications: 0.
Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies
ClinicalTrials.gov study NCT03178942. IPD Sharing: NO. Countries: 3. Publications: 0.
Better Disease Control by Multidrug Regimen in Scabies
ClinicalTrials.gov study NCT05198947. IPD Sharing: NO. Countries: 0. Publications: 16.
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