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8 results for “Serosurvey”
Data from: Serosurvey of SARS-COV-2 at a large public university
<p><strong>Objective</strong>: This study investigated the seroprevalence of SARS-CoV-2 antibodies among adults over 18 years.</p> <p><strong>Design</strong>: Prospective cohort study.</p> <p><strong>Settings</strong>: a population-based study among the big university community.</p> <p><strong>Participants</strong>: This study took volunteers over five days and recruited adult 1064 participants.</p> <p><strong>Primary outcome measures</strong>: We conducted a seroprevalence in our community with SARS-CoV-2-specific antibodies due to previous exposure to SARS-CoV-2 and/or vaccination.</p> <p><strong>Results</strong>: The seroprevalence of the anti-receptor binding domain (RBD) antibody was 90% by a lateral flow assay and 88% by a semi-quantitative chemiluminescent immunoassay. The seroprevalence for anti-nucleocapsid (NC) was 20%. In addition, individuals with previous natural COVID infection plus vaccination had higher anti-RBD antibody levels compared to those who had vaccination only or infection only. Individuals who had a breakthrough infection had the highest anti-RBD antibody levels.</p> <p><strong>Conclusion</strong>: Accurate estimates of the cumulative incidence of SARS-CoV-2 infection can inform the development of university risk mitigation protocols such as encouraging booster shots, extending mask mandates, or reverting to online classes. It could help us to have clear guidance to act at the first sign of the next surge as well, especially since there is a surge of COVID subvariant infections.</p>
SARS-COV2 Pandemic Serosurvey and Blood Sampling
ClinicalTrials.gov study NCT04334954. IPD Sharing: YES. Countries: 1. Publications: 1.
Data from: Serosurvey of SARS-COV-2 at a large public university
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Data from: The burden of Hepatitis C virus infection in Punjab, India: a population-based serosurvey
Introduction: Hepatitis C virus (HCV) infection prevalence is believed to be elevated in Punjab, India; however, state-wide prevalence data are not available. An understanding of HCV prevalence, risk factors and genotype distribution can be used to plan control measures in Punjab. Methods: A cross-sectional, state-wide, population-based serosurvey using a multi-stage stratified cluster sampling design was conducted October 2013 to April 2014. Children aged >5 years and adults were eligible to participate. Demographic and risk behavior data were collected, and serologic specimens were obtained and tested for anti-HCV antibody, HCV Ribonucleic acid (RNA) on anti-HCV positive samples, and HCV genotype. Prevalence estimates and adjusted odds ratios for risk factors were calculated from weighted data and stratified by urban/rural residence. Results: 5,543 individuals participated in the study with an overall weighted anti-HCV prevalence of 3.6% (95% Confidence Interval [CI]: 3.0%-4.2%) and chronic infection (HCV Ribonucleic acid test positive) of 2.6% (95% CI: 2.0%-3.1%). Anti-HCV was associated with being male (adjusted odds ratio 1.52; 95% CI: 1.08-2.14), living in a rural area (adjusted odds ratio 2.53; 95% CI: 1.62-3.95) and was most strongly associated with those aged 40-49 (adjusted odds ratio 40-49 vs 19-29-year-olds 3.41; 95% CI: 1.90-6.11). Anti-HCV prevalence increased with each blood transfusion received (adjusted odds ratio 1.36; 95% CI: 1.10-1.68) and decreased with increasing education, (adjusted odds ratio 0.37 for graduate-level vs. primary school/no education; 95% CI: 0.16-0.82). Genotype 3 (58%) was most common among infected individuals. Discussion: The study findings, including the overall prevalence of chronic HCV infection, associated risk factors and demographic characteristics, and genotype distribution can guide prevention and control efforts, including treatment provision. In addition to high-risk populations, efforts targeting rural areas and adults aged >40 would be the most effective for identifying infected individuals.
Police COVID-19 Serosurvey
ClinicalTrials.gov study NCT04643444. IPD Sharing: NO. Countries: 1. Publications: 1.
A Serosurvey Study of Hand, Foot, and Mouth Disease in Indonesia
ClinicalTrials.gov study NCT05637229. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: The burden of Hepatitis C virus infection in Punjab, India: a population-based serosurvey
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SARS-COV2 Pandemic Serosurvey in a Rare Disease Population
ClinicalTrials.gov study NCT04609085. IPD Sharing: YES. Countries: 1. Publications: 0.
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OpenNeuro
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