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10 results for “Superparamagnetic Iron Oxide nanoparticles”
Effect of superparamagnetic iron oxide nanoparticles on glucose homeostasis on type 2 diabetes experimental model
<p>The data correspond to figures in the paper by Ali, L.M.A. et al. Life Sciences 245 (2020) 117361. doi:10.1016/j.lfs.2020.117361.</p>
the Accuracy and Safety of Coronary Artery Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle
ClinicalTrials.gov study NCT05032937. IPD Sharing: NO. Countries: 1. Publications: 2.
Characterization of the Shape Anisotropy of Superparamagnetic Iron Oxide Nanoparticles during Thermal Decomposition
<p>Magnetosomes are near-perfect intracellular magnetite nanocrystals found in magnetotactic bacteria. Their synthetic imitation, known as superparamagnetic iron oxide nanoparticles (SPIONs), have found applications in a variety of (nano)medicinal fields such as magnetic resonance imaging contrast agents, multimodal imaging and drug carriers. In order to perform these functions in medicine, shape and size control of the SPIONs is vital. We sampled SPIONs at ten-minutes intervals during the high-temperature thermal decomposition reaction. Their shape (sphericity and anisotropy) and geometric description (volume and surface area) were retrieved using three-dimensional imaging techniques, which allowed to reconstruct each particle in three dimensions, followed by stereological quantification methods. The results, supported by small angle X-ray scattering characterization, reveal that SPIONs initially have a spherical shape, then grow increasingly asymmetric and irregular. A high heterogeneity in volume at the initial stages makes place for lower particle volume dispersity at later stages. The SPIONs settled into a preferred orientation on the support used for transmission electron microscopy imaging, which hides the extent of their anisotropic nature in the axial dimension, there by biasing the interpretation of standard 2D micrographs. This information could be feedback into the design of the chemical processes and the characterization strategies to improve the current applications of SPIONs in nanomedicine.</p>
Data from: New MRI contrast agents based on silicon nanotubes loaded with superparamagnetic iron oxide nanoparticles
This article describes the preparation and fundamental properties of a new possible material as a MRI contrast agent based on the incorporation of preformed iron oxide nanocrystals into hollow silicon nanotubes. Specifically, superparamagnetic iron oxide nanoparticles Fe3O4 of two different average sizes (5 nm and 8 nm) were loaded into silicon nanotubes of two different shell thicknesses (40 nm and 70 nm). To achieve proper aqueous solubility, the nanotubes were functionalized with an outer polyethylene glycol (PEG)-diacid (600) moiety via an aminopropyl linkage. Relaxometry parameters r1 and r2 were measured, with the corresponding r2/r1 ratios in PBS confirming the expected negative contrast agent behaviour for these materials. For a given nanocrystal size, the observed r2 values are found to be inversely proportional to nanotube wall thickness, thereby demonstrating the role of nanostructured silicon template on associated relaxometry properties.
Data from: New MRI contrast agents based on silicon nanotubes loaded with superparamagnetic iron oxide nanoparticles
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Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle
ClinicalTrials.gov study NCT06010537. IPD Sharing: Not stated. Countries: 1. Publications: 0.
In Vivo Characterization of Inflammation With Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging
ClinicalTrials.gov study NCT02511028. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Transcriptomic fingerprints of C. elegans exposed to superparamagnetic iron oxide nanoparticles coated with a monolayer of bovine serum albumin (BSA-SPIONs)
GEO Series GSE93186. Caenorhabditis elegans. 6 samples. Type: Expression profiling by array.
Transcriptomic fingerprints of C. elegans exposed to citrate coated superparamagnetic iron oxide nanoparticles (C-SPIONs) and to superparamagnetic iron oxide nanoparticles coated with a monolayer of b
GEO Series GSE93188. Caenorhabditis elegans. 12 samples. Type: Expression profiling by array.
Transcriptomic fingerprints of C. elegans exposed to citrate coated superparamagnetic iron oxide nanoparticles (C-SPIONs)
GEO Series GSE93187. Caenorhabditis elegans. 6 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.